Vocar.0006s0021.1 (32894136)

Aliases : 32894136

Description : Vitamin B12-dependent methionine synthase, activation domain; Pterin-binding domain; Cobalamin (vitamin B12)-binding module, cap domain; Cobalamin (vitamin B12)-binding domain; Homocysteine-binding domain [Interproscan].

Gene families : OG_01_0001464 (OrthoFinder) Phylogenetic Tree(s): OG0001464_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Vocar.0006s0021.1
Cluster	HCCA: Cluster_1

Target	Alias	Description	ECC score	Gene Family Method
Sro803_g204830.1	Contig386.g5197	Probable methionine synthase	0.01	OrthoFinder
SymbC1.scaffold4.215	4.215	Pterin-binding domain; Nitrite/sulphite reductase 4Fe-4S...	0.01	OrthoFinder
Transcript_contig_78217	78217	Pterin-binding domain; Homocysteine-binding domain...	0.01	OrthoFinder
Transcript_contig_90572	90572	Vitamin B12-dependent methionine synthase, activation...	0.02	OrthoFinder

Type	GO Term	Name	Evidence	Source
BP	GO:0000096	sulfur amino acid metabolic process	None	Extended
BP	GO:0000097	sulfur amino acid biosynthetic process	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006555	methionine metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006790	sulfur compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008168	methyltransferase activity	None	Extended
MF	GO:0008172	S-methyltransferase activity	None	Extended
BP	GO:0008652	cellular amino acid biosynthetic process	None	Extended
MF	GO:0008705	methionine synthase activity	IEA	Interproscan
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009066	aspartate family amino acid metabolic process	None	Extended
BP	GO:0009067	aspartate family amino acid biosynthetic process	None	Extended
BP	GO:0009086	methionine biosynthetic process	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016053	organic acid biosynthetic process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016741	transferase activity, transferring one-carbon groups	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0019842	vitamin binding	None	Extended
MF	GO:0031419	cobalamin binding	IEA	Interproscan
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042084	5-methyltetrahydrofolate-dependent methyltransferase activity	None	Extended
BP	GO:0042558	pteridine-containing compound metabolic process	IEA	Interproscan
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044272	sulfur compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
BP	GO:0046394	carboxylic acid biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046872	metal ion binding	IEA	Interproscan
MF	GO:0046906	tetrapyrrole binding	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended
BP	GO:1901605	alpha-amino acid metabolic process	None	Extended
BP	GO:1901607	alpha-amino acid biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
MF	GO:0003852	2-isopropylmalate synthase activity	IEP	Enrichment
MF	GO:0004175	endopeptidase activity	IEP	Enrichment
MF	GO:0004177	aminopeptidase activity	IEP	Enrichment
MF	GO:0004190	aspartic-type endopeptidase activity	IEP	Enrichment
MF	GO:0004252	serine-type endopeptidase activity	IEP	Enrichment
MF	GO:0004425	indole-3-glycerol-phosphate synthase activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
CC	GO:0005743	mitochondrial inner membrane	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006163	purine nucleotide metabolic process	IEP	Enrichment
BP	GO:0006164	purine nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0006188	IMP biosynthetic process	IEP	Enrichment
BP	GO:0006189	'de novo' IMP biosynthetic process	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006457	protein folding	IEP	Enrichment
BP	GO:0006508	proteolysis	IEP	Enrichment
BP	GO:0006551	leucine metabolic process	IEP	Enrichment
BP	GO:0006629	lipid metabolic process	IEP	Enrichment
BP	GO:0006743	ubiquinone metabolic process	IEP	Enrichment
BP	GO:0006744	ubiquinone biosynthetic process	IEP	Enrichment
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Enrichment
BP	GO:0006754	ATP biosynthetic process	IEP	Enrichment
BP	GO:0006811	ion transport	IEP	Enrichment
BP	GO:0006812	cation transport	IEP	Enrichment
BP	GO:0006839	mitochondrial transport	IEP	Enrichment
BP	GO:0006848	pyruvate transport	IEP	Enrichment
BP	GO:0006850	mitochondrial pyruvate transmembrane transport	IEP	Enrichment
MF	GO:0008233	peptidase activity	IEP	Enrichment
MF	GO:0008236	serine-type peptidase activity	IEP	Enrichment
MF	GO:0008238	exopeptidase activity	IEP	Enrichment
BP	GO:0009098	leucine biosynthetic process	IEP	Enrichment
BP	GO:0009117	nucleotide metabolic process	IEP	Enrichment
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009124	nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009126	purine nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009141	nucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009142	nucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009144	purine nucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009145	purine nucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009152	purine ribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009161	ribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009165	nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009199	ribonucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009201	ribonucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009206	purine ribonucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009259	ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009260	ribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0015711	organic anion transport	IEP	Enrichment
BP	GO:0015718	monocarboxylic acid transport	IEP	Enrichment
BP	GO:0015849	organic acid transport	IEP	Enrichment
BP	GO:0015985	energy coupled proton transport, down electrochemical gradient	IEP	Enrichment
BP	GO:0015986	ATP synthesis coupled proton transport	IEP	Enrichment
CC	GO:0016459	myosin complex	IEP	Enrichment
MF	GO:0016462	pyrophosphatase activity	IEP	Enrichment
MF	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	IEP	Enrichment
MF	GO:0016787	hydrolase activity	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
MF	GO:0017171	serine hydrolase activity	IEP	Enrichment
BP	GO:0018130	heterocycle biosynthetic process	IEP	Enrichment
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Enrichment
BP	GO:0019538	protein metabolic process	IEP	Enrichment
BP	GO:0019637	organophosphate metabolic process	IEP	Enrichment
BP	GO:0019693	ribose phosphate metabolic process	IEP	Enrichment
CC	GO:0019866	organelle inner membrane	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
CC	GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain	IEP	Enrichment
BP	GO:0034220	ion transmembrane transport	IEP	Enrichment
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
BP	GO:0042180	cellular ketone metabolic process	IEP	Enrichment
BP	GO:0042181	ketone biosynthetic process	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Enrichment
CC	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)	IEP	Enrichment
MF	GO:0045300	acyl-[acyl-carrier-protein] desaturase activity	IEP	Enrichment
BP	GO:0046034	ATP metabolic process	IEP	Enrichment
BP	GO:0046040	IMP metabolic process	IEP	Enrichment
BP	GO:0046390	ribose phosphate biosynthetic process	IEP	Enrichment
MF	GO:0046912	acyltransferase, acyl groups converted into alkyl on transfer	IEP	Enrichment
BP	GO:0046942	carboxylic acid transport	IEP	Enrichment
MF	GO:0047429	nucleoside-triphosphate diphosphatase activity	IEP	Enrichment
MF	GO:0051082	unfolded protein binding	IEP	Enrichment
BP	GO:0055085	transmembrane transport	IEP	Enrichment
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Enrichment
MF	GO:0070001	aspartic-type peptidase activity	IEP	Enrichment
BP	GO:0072521	purine-containing compound metabolic process	IEP	Enrichment
BP	GO:0072522	purine-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0090407	organophosphate biosynthetic process	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
BP	GO:0098655	cation transmembrane transport	IEP	Enrichment
BP	GO:0098656	anion transmembrane transport	IEP	Enrichment
BP	GO:0098660	inorganic ion transmembrane transport	IEP	Enrichment
BP	GO:0098662	inorganic cation transmembrane transport	IEP	Enrichment
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Enrichment
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment
BP	GO:1901475	pyruvate transmembrane transport	IEP	Enrichment
BP	GO:1901661	quinone metabolic process	IEP	Enrichment
BP	GO:1901663	quinone biosynthetic process	IEP	Enrichment
BP	GO:1902600	proton transmembrane transport	IEP	Enrichment
BP	GO:1903825	organic acid transmembrane transport	IEP	Enrichment
BP	GO:1905039	carboxylic acid transmembrane transport	IEP	Enrichment
BP	GO:1990542	mitochondrial transmembrane transport	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR000489	Pterin-binding_dom	503	741
IPR000489	Pterin-binding_dom	1207	1445
IPR000489	Pterin-binding_dom	1911	2149
IPR006158	Cobalamin-bd	2323	2416
IPR003726	HCY_dom	153	461
IPR003726	HCY_dom	857	1165
IPR003726	HCY_dom	1561	1869
IPR004223	VitB12-dep_Met_synth_activ_dom	2517	2793
IPR003759	Cbl-bd_cap	2226	2300

External Links

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Vocar.0006s0021.1 (32894136)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation