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GO:0004252: serine-type endopeptidase activity (Molecular function)

"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE]


There are 7476 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_4 Cyanophora paradoxa 2.23 % 0.003004 0.039958
Cluster_212 Cyanophora paradoxa 8.47 % 2e-06 0.000124
Cluster_53 Cyanophora paradoxa 3.85 % 0.012964 0.029134
Cluster_71 Chromochloris zofingiensis 3.31 % 9.4e-05 0.027611
Cluster_486 Emiliania huxleyi 50.0 % 0.00544 0.035357
Cluster_645 Emiliania huxleyi 100.0 % 7e-06 0.000132
Cluster_164 Emiliania huxleyi 3.95 % 0.001194 0.011261
Cluster_35 Emiliania huxleyi 10.61 % 0.0 0.0
Cluster_176 Emiliania huxleyi 5.56 % 4.6e-05 0.004495
Cluster_149 Haematococcus lacustris 4.08 % 0.00086 0.009339
Cluster_94 Phaeodactylum tricornutum 5.77 % 0.000803 0.049807
Cluster_189 Seminavis robusta 3.12 % 0.007619 0.03381
Cluster_28 Seminavis robusta 5.13 % 0.000324 0.011351
Cluster_38 Seminavis robusta 2.82 % 8.6e-05 0.003401
Cluster_464 Seminavis robusta 33.33 % 0.012436 0.042637
Cluster_8 Seminavis robusta 10.17 % 0.0 0.0
Cluster_46 Seminavis robusta 5.97 % 0.000181 0.003792
Cluster_106 Seminavis robusta 3.7 % 0.00476 0.021762
Cluster_565 Seminavis robusta 50.0 % 0.000103 0.001849
Cluster_111 Seminavis robusta 4.21 % 0.000685 0.012107
Cluster_33 Thalassiosira pseudonana 2.52 % 0.004238 0.047086
Sequences (7476) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro and Family associations disabled for items with more than 5000 associated sequences !