lcl|LHPG02000005.1_cds_PRW58281.1_7787 (PRW58281)

Aliases : PRW58281

Description : DNA topoisomerase 2

Gene families : OG_01_0001339 (OrthoFinder) Phylogenetic Tree(s): OG0001339_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: lcl\|LHPG02000005.1_cds_PRW58281.1_7787
Cluster	HCCA: Cluster_34

Target	Alias	Description	ECC score	Gene Family Method
Cpa\|evm.model.tig00021432.55	tig00021432_g21247.t1	DNA topoisomerase 2 OS=Pisum sativum	0.04	OrthoFinder
Cre01.g009250	30789357, TOP2	Cell cycle.interphase.DNA replication.preinitiation.TOP2...	0.04	OrthoFinder
Cz11g19140.t1	No alias	DNA topoisomerase, type IIA, subunit B, domain 2; TOPRIM...	0.02	OrthoFinder
Dusal.0487s00005.1	33203263	Histidine kinase/HSP90-like ATPase; C-terminal...	0.02	OrthoFinder
EOD17812	No alias	Putative DNA topoisomerase II [Ensembl].	0.01	OrthoFinder
EOD22469	No alias	DNA topoisomerase, type IIA, subunit A/C-terminal; DNA...	0.04	OrthoFinder
OT_13G00120.1	No alias	TOPRIM domain; DNA topoisomerase, type IIA, subunit B,...	0.06	OrthoFinder
PTI_12G02730.1	No alias	TOPRIM domain; DNA topoisomerase, type IIA, subunit...	0.03	OrthoFinder
Sro150_g068880.1	Contig1519.g13851	DNA topoisomerase 2 top-2	0.03	OrthoFinder
SymbC1.scaffold1232.13	1232.13	C-terminal associated domain of TOPRIM; DNA...	0.02	OrthoFinder
TP10G02490.1	No alias	DNA topoisomerase, type IIA, subunit A/C-terminal;...	0.01	OrthoFinder
Vocar.0024s0199.1	32890400	Histidine kinase/HSP90-like ATPase; TOPRIM domain; DNA...	0.05	OrthoFinder
XM_002501981.1	MICPUN_58377, 58377	DNA topoisomerase, type IIA, subunit A/C-terminal; DNA...	0.03	OrthoFinder
XM_003057460.1	MicpuC2_46870, 46870	TOPRIM domain; DNA topoisomerase, type IIA, subunit...	0.02	OrthoFinder
lcl\|BLLF01001294.1_cds_GFH18390.1_12867	HaLaN_15188, GFH18390	DNA topoisomerase 2	0.02	OrthoFinder
lcl\|VRMN01000001.1_cds_KAA8497819.1_6772	KAA8497819	DNA topoisomerase 2	0.04	OrthoFinder
lcl\|VRMN01000008.1_cds_KAA8492722.1_2458	KAA8492722	DNA topoisomerase 2	0.04	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	None	Extended
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
MF	GO:0008094	ATPase, acting on DNA	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
MF	GO:0016887	ATPase	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000272	polysaccharide catabolic process	IEP	Enrichment
MF	GO:0000287	magnesium ion binding	IEP	Enrichment
CC	GO:0000786	nucleosome	IEP	Enrichment
MF	GO:0003774	motor activity	IEP	Enrichment
MF	GO:0003777	microtubule motor activity	IEP	Enrichment
MF	GO:0003937	IMP cyclohydrolase activity	IEP	Enrichment
MF	GO:0003997	acyl-CoA oxidase activity	IEP	Enrichment
MF	GO:0004451	isocitrate lyase activity	IEP	Enrichment
MF	GO:0004474	malate synthase activity	IEP	Enrichment
MF	GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	IEP	Enrichment
MF	GO:0005515	protein binding	IEP	Enrichment
MF	GO:0005534	galactose binding	IEP	Enrichment
CC	GO:0005681	spliceosomal complex	IEP	Enrichment
BP	GO:0005975	carbohydrate metabolic process	IEP	Enrichment
BP	GO:0005976	polysaccharide metabolic process	IEP	Enrichment
BP	GO:0006081	cellular aldehyde metabolic process	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006097	glyoxylate cycle	IEP	Enrichment
BP	GO:0006334	nucleosome assembly	IEP	Enrichment
BP	GO:0006635	fatty acid beta-oxidation	IEP	Enrichment
BP	GO:0006904	vesicle docking involved in exocytosis	IEP	Enrichment
BP	GO:0006928	movement of cell or subcellular component	IEP	Enrichment
BP	GO:0007017	microtubule-based process	IEP	Enrichment
BP	GO:0007018	microtubule-based movement	IEP	Enrichment
BP	GO:0007275	multicellular organism development	IEP	Enrichment
MF	GO:0008017	microtubule binding	IEP	Enrichment
MF	GO:0008092	cytoskeletal protein binding	IEP	Enrichment
BP	GO:0009056	catabolic process	IEP	Enrichment
BP	GO:0009057	macromolecule catabolic process	IEP	Enrichment
BP	GO:0009062	fatty acid catabolic process	IEP	Enrichment
BP	GO:0009555	pollen development	IEP	Enrichment
BP	GO:0010498	proteasomal protein catabolic process	IEP	Enrichment
MF	GO:0015631	tubulin binding	IEP	Enrichment
BP	GO:0016042	lipid catabolic process	IEP	Enrichment
BP	GO:0016052	carbohydrate catabolic process	IEP	Enrichment
MF	GO:0016160	amylase activity	IEP	Enrichment
MF	GO:0016161	beta-amylase activity	IEP	Enrichment
MF	GO:0016462	pyrophosphatase activity	IEP	Enrichment
MF	GO:0016651	oxidoreductase activity, acting on NAD(P)H	IEP	Enrichment
MF	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	IEP	Enrichment
MF	GO:0016742	hydroxymethyl-, formyl- and related transferase activity	IEP	Enrichment
MF	GO:0016787	hydrolase activity	IEP	Enrichment
MF	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	IEP	Enrichment
MF	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0016833	oxo-acid-lyase activity	IEP	Enrichment
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Enrichment
CC	GO:0018995	host cellular component	IEP	Enrichment
MF	GO:0019238	cyclohydrolase activity	IEP	Enrichment
BP	GO:0019395	fatty acid oxidation	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
BP	GO:0022406	membrane docking	IEP	Enrichment
BP	GO:0030163	protein catabolic process	IEP	Enrichment
BP	GO:0030258	lipid modification	IEP	Enrichment
BP	GO:0030328	prenylcysteine catabolic process	IEP	Enrichment
BP	GO:0030329	prenylcysteine metabolic process	IEP	Enrichment
BP	GO:0032501	multicellular organismal process	IEP	Enrichment
BP	GO:0032502	developmental process	IEP	Enrichment
BP	GO:0032787	monocarboxylic acid metabolic process	IEP	Enrichment
CC	GO:0032993	protein-DNA complex	IEP	Enrichment
CC	GO:0033643	host cell part	IEP	Enrichment
CC	GO:0033646	host intracellular part	IEP	Enrichment
CC	GO:0033647	host intracellular organelle	IEP	Enrichment
CC	GO:0033648	host intracellular membrane-bounded organelle	IEP	Enrichment
BP	GO:0034220	ion transmembrane transport	IEP	Enrichment
BP	GO:0034440	lipid oxidation	IEP	Enrichment
BP	GO:0034728	nucleosome organization	IEP	Enrichment
CC	GO:0042025	host cell nucleus	IEP	Enrichment
BP	GO:0042219	cellular modified amino acid catabolic process	IEP	Enrichment
MF	GO:0043015	gamma-tubulin binding	IEP	Enrichment
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0044242	cellular lipid catabolic process	IEP	Enrichment
BP	GO:0044262	cellular carbohydrate metabolic process	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
CC	GO:0044815	DNA packaging complex	IEP	Enrichment
BP	GO:0046034	ATP metabolic process	IEP	Enrichment
BP	GO:0046487	glyoxylate metabolic process	IEP	Enrichment
MF	GO:0046912	acyltransferase, acyl groups converted into alkyl on transfer	IEP	Enrichment
MF	GO:0048029	monosaccharide binding	IEP	Enrichment
BP	GO:0048229	gametophyte development	IEP	Enrichment
BP	GO:0048278	vesicle docking	IEP	Enrichment
BP	GO:0048856	anatomical structure development	IEP	Enrichment
BP	GO:0051640	organelle localization	IEP	Enrichment
BP	GO:0065004	protein-DNA complex assembly	IEP	Enrichment
BP	GO:0071824	protein-DNA complex subunit organization	IEP	Enrichment
BP	GO:0072329	monocarboxylic acid catabolic process	IEP	Enrichment
BP	GO:0098655	cation transmembrane transport	IEP	Enrichment
BP	GO:0098660	inorganic ion transmembrane transport	IEP	Enrichment
BP	GO:0098662	inorganic cation transmembrane transport	IEP	Enrichment
BP	GO:0140029	exocytic process	IEP	Enrichment
BP	GO:0140056	organelle localization by membrane tethering	IEP	Enrichment
BP	GO:1901565	organonitrogen compound catabolic process	IEP	Enrichment
BP	GO:1901575	organic substance catabolic process	IEP	Enrichment
BP	GO:1902600	proton transmembrane transport	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR002205	Topo_IIA_A/C	696	1147
IPR013506	Topo_IIA_bsu_dom2	272	420
IPR003594	HATPase_C	81	227
IPR031660	TOPRIM_C	569	693
IPR006171	TOPRIM_domain	455	553

External Links

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lcl|LHPG02000005.1_cds_PRW58281.1_7787 (PRW58281)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation