GO:0003918: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (Molecular function)

"Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2." [PMID:8811192]


There are 4153 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_40 Cyanophora paradoxa 1.4 % 2.2e-05 0.000138
Cluster_25 Chlorella sorokiniana 0.93 % 0.004095 0.043428
Cluster_145 Dunaliella sp. 2.22 % 0.010738 0.039969
Cluster_132 Emiliania huxleyi 1.05 % 0.017123 0.037485
Cluster_84 Micromonas commoda 3.64 % 0.000176 0.002962
Cluster_42 Phaeodactylum tricornutum 2.67 % 0.00037 0.001512
Cluster_6 Porphyridium purpureum 1.98 % 0.001506 0.00607
Cluster_42 Seminavis robusta 1.1 % 0.012006 0.030872
Sequences (4153) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms