OT_12G02000.1

Description : DNA topoisomerase I, catalytic core, eukaryotic-type; DNA topoisomerase I, DNA binding, eukaryotic-type; Topoisomerase I C-terminal domain [Interproscan].

Gene families : OG_01_0002413 (OrthoFinder) Phylogenetic Tree(s): OG0002413_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: OT_12G02000.1
Cluster	HCCA: Cluster_36

Target	Alias	Description	ECC score	Gene Family Method	Actions
lcl\|BLLF01002372.1_cds_GFH23824.1_18301	HaLaN_21508, GFH23824	DNA topoisomerase 1	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	None	Extended
MF	GO:0003917	DNA topoisomerase type I (single strand cut, ATP-independent) activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000796	condensin complex	IEP	Enrichment
MF	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity	IEP	Enrichment
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Enrichment
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEP	Enrichment
MF	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity	IEP	Enrichment
MF	GO:0004672	protein kinase activity	IEP	Enrichment
MF	GO:0005215	transporter activity	IEP	Enrichment
MF	GO:0005216	ion channel activity	IEP	Enrichment
MF	GO:0005261	cation channel activity	IEP	Enrichment
CC	GO:0005575	cellular_component	IEP	Enrichment
CC	GO:0005783	endoplasmic reticulum	IEP	Enrichment
BP	GO:0006163	purine nucleotide metabolic process	IEP	Enrichment
BP	GO:0006164	purine nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0006323	DNA packaging	IEP	Enrichment
BP	GO:0006366	transcription by RNA polymerase II	IEP	Enrichment
BP	GO:0006464	cellular protein modification process	IEP	Enrichment
BP	GO:0006468	protein phosphorylation	IEP	Enrichment
BP	GO:0006486	protein glycosylation	IEP	Enrichment
BP	GO:0006629	lipid metabolic process	IEP	Enrichment
BP	GO:0006754	ATP biosynthetic process	IEP	Enrichment
BP	GO:0006793	phosphorus metabolic process	IEP	Enrichment
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Enrichment
BP	GO:0006810	transport	IEP	Enrichment
BP	GO:0006811	ion transport	IEP	Enrichment
BP	GO:0006812	cation transport	IEP	Enrichment
BP	GO:0006886	intracellular protein transport	IEP	Enrichment
BP	GO:0007076	mitotic chromosome condensation	IEP	Enrichment
MF	GO:0008194	UDP-glycosyltransferase activity	IEP	Enrichment
CC	GO:0008303	caspase complex	IEP	Enrichment
MF	GO:0008324	cation transmembrane transporter activity	IEP	Enrichment
BP	GO:0009117	nucleotide metabolic process	IEP	Enrichment
BP	GO:0009141	nucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009142	nucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009144	purine nucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009145	purine nucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009152	purine ribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009165	nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009199	ribonucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009201	ribonucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009206	purine ribonucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009259	ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009260	ribonucleotide biosynthetic process	IEP	Enrichment
MF	GO:0015075	ion transmembrane transporter activity	IEP	Enrichment
MF	GO:0015078	proton transmembrane transporter activity	IEP	Enrichment
MF	GO:0015252	proton channel activity	IEP	Enrichment
MF	GO:0015267	channel activity	IEP	Enrichment
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Enrichment
BP	GO:0015985	energy coupled proton transport, down electrochemical gradient	IEP	Enrichment
BP	GO:0015986	ATP synthesis coupled proton transport	IEP	Enrichment
CC	GO:0016021	integral component of membrane	IEP	Enrichment
BP	GO:0016255	attachment of GPI anchor to protein	IEP	Enrichment
MF	GO:0016301	kinase activity	IEP	Enrichment
BP	GO:0016310	phosphorylation	IEP	Enrichment
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Enrichment
MF	GO:0016779	nucleotidyltransferase activity	IEP	Enrichment
BP	GO:0019693	ribose phosphate metabolic process	IEP	Enrichment
BP	GO:0022402	cell cycle process	IEP	Enrichment
MF	GO:0022803	passive transmembrane transporter activity	IEP	Enrichment
MF	GO:0022857	transmembrane transporter activity	IEP	Enrichment
MF	GO:0022890	inorganic cation transmembrane transporter activity	IEP	Enrichment
CC	GO:0030126	COPI vesicle coat	IEP	Enrichment
BP	GO:0030261	chromosome condensation	IEP	Enrichment
CC	GO:0031224	intrinsic component of membrane	IEP	Enrichment
CC	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain	IEP	Enrichment
BP	GO:0034220	ion transmembrane transport	IEP	Enrichment
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0035251	UDP-glucosyltransferase activity	IEP	Enrichment
BP	GO:0036211	protein modification process	IEP	Enrichment
CC	GO:0042765	GPI-anchor transamidase complex	IEP	Enrichment
CC	GO:0043227	membrane-bounded organelle	IEP	Enrichment
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Enrichment
BP	GO:0043412	macromolecule modification	IEP	Enrichment
BP	GO:0043413	macromolecule glycosylation	IEP	Enrichment
CC	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)	IEP	Enrichment
BP	GO:0046034	ATP metabolic process	IEP	Enrichment
BP	GO:0046390	ribose phosphate biosynthetic process	IEP	Enrichment
MF	GO:0046527	glucosyltransferase activity	IEP	Enrichment
MF	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	IEP	Enrichment
BP	GO:0051179	localization	IEP	Enrichment
BP	GO:0051234	establishment of localization	IEP	Enrichment
BP	GO:0055085	transmembrane transport	IEP	Enrichment
BP	GO:0070085	glycosylation	IEP	Enrichment
BP	GO:0072521	purine-containing compound metabolic process	IEP	Enrichment
BP	GO:0072522	purine-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0098655	cation transmembrane transport	IEP	Enrichment
BP	GO:0098660	inorganic ion transmembrane transport	IEP	Enrichment
BP	GO:0098662	inorganic cation transmembrane transport	IEP	Enrichment
CC	GO:0098796	membrane protein complex	IEP	Enrichment
CC	GO:0110165	cellular anatomical entity	IEP	Enrichment
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Enrichment
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Enrichment
BP	GO:1902600	proton transmembrane transport	IEP	Enrichment
BP	GO:1903047	mitotic cell cycle process	IEP	Enrichment
CC	GO:1905369	endopeptidase complex	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR013500	TopoI_cat_euk	452	675
IPR025834	TopoI_C_dom	690	759
IPR008336	TopoI_DNA-bd_euk	236	447

External Links

No external refs found!

OT_12G02000.1

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation