| Cluster | HCCA: Cluster_83 vs Cluster_169 graph comparison <a href="/cluster/view/95" class="qtip_tooltip" qtip_href="/cluster/tooltip/95">Cluster_143</a></strong></td> <td><a href="/cluster/view/95" data-toggle="tooltip" data-placement="top" title="View cluster as table"><i class="fa fa-list"></i></a> <a href="/cluster/graph/95" data-toggle="tooltip" data-placement="top" title="View cluster as graph"><i class="fa fa-sitemap"></i></a> <a href="/profile_comparison/cluster/95" data-toggle="tooltip" data-placement="top" title="Compare profiles in this cluster"><i class="fa fa-area-chart"></i></a> <a href="/heatmap/cluster/95" data-toggle="tooltip" data-placement="top" title="Heatmap of profiles in this cluster"><i class="fa fa-table"></i></a></td> </tr> </tbody> </table> </div> </div> <br> <br> <h3 class="banner-blue" id="annotation">Functional Annotation</h3> <div class="panel with-nav-tabs panel-default"> <div class="panel-heading"> <ul class="nav nav-tabs"> <li class="active"><a href="#tab1default" data-toggle="tab">GO</a></li> <li><a href="#tab2default" data-toggle="tab">Predicted GO</a></li> <li><a href="#tab3default" data-toggle="tab">InterPro</a></li> </ul> </div> <div> <div class="tab-content"> <div class="tab-pane fade in active" id="tab1default"> <div class="table-responsive"> <table class="table table-striped table-fixed" id="go_table"> <thead> <tr> <th class="col-xs-1" data-sort="string-ins"><span class="sort-icon"></span>Type</th> <th class="col-xs-2" data-sort="string-ins"><span class="sort-icon"></span><abbr title="Click to show help" href="/help/go" data-target="#helpModal">GO</abbr> Term</th> <th class="col-xs-6" data-sort="string-ins"><span class="sort-icon"></span>Name</th> <th class="col-xs-1" data-sort="string-ins"><span class="sort-icon"></span>Evidence</th> <th class="col-xs-2" data-sort="string-ins"><span class="sort-icon"></span>Source</th> </tr> </thead> <tbody> <tr> <td class="col-xs-12"><p>No GO annotation available for this sequence</p></td> </tr> </tbody> </table> </div> <div class="panel-body"> <a href="#" id="go_toggle">Toggle parental</a> </div> </div> <div class="tab-pane fade" id="tab2default"> <div class="table-responsive"> <table class="table table-striped table-fixed" id="predicted_go_table"> <thead> <tr> <th class="col-xs-1" data-sort="string-ins"><span class="sort-icon"></span>Type</th> <th class="col-xs-2" data-sort="string-ins"><span class="sort-icon"></span><abbr title="Click to show help" href="/help/go" data-target="#helpModal">GO</abbr> Term</th> <th class="col-xs-6" data-sort="string-ins"><span class="sort-icon"></span>Name</th> <th class="col-xs-1" data-sort="string-ins"><span class="sort-icon"></span>Evidence</th> <th class="col-xs-2" data-sort="string-ins"><span class="sort-icon"></span>Source</th> </tr> </thead> <tbody> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/128" data-toggle="tooltip" data-placement="top" title=""Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response." [GOC:bf, GOC:mcc, PMID:10966457, PMID:20223701, PMID:9191038]">GO:0000155</a></td> <td class="col-xs-6">phosphorelay sensor kinase activity</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/3008" data-toggle="tooltip" data-placement="top" title=""Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate." [GOC:mah]">GO:0004112</a></td> <td class="col-xs-6">cyclic-nucleotide phosphodiesterase activity</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/3010" data-toggle="tooltip" data-placement="top" title=""Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate." [EC:3.1.4.17]">GO:0004114</a></td> <td class="col-xs-6">3',5'-cyclic-nucleotide phosphodiesterase activity</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/3495" data-toggle="tooltip" data-placement="top" title=""Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP." [MetaCyc:PROTEIN-KINASE-RXN]">GO:0004672</a></td> <td class="col-xs-6">protein kinase activity</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/3496" data-toggle="tooltip" data-placement="top" title=""Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine." [EC:2.7.13.3, GOC:mah]">GO:0004673</a></td> <td class="col-xs-6">protein histidine kinase activity</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/3955" data-toggle="tooltip" data-placement="top" title=""Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size)." [GOC:cy, GOC:mtg_transport, GOC:pr, ISBN:0815340729]">GO:0005216</a></td> <td class="col-xs-6">ion channel activity</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">BP</td> <td class="col-xs-2"><a href="/go/view/5292" data-toggle="tooltip" data-placement="top" title=""The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein." [GOC:dos, GOC:dph, GOC:jl, GOC:mah]">GO:0006810</a></td> <td class="col-xs-6">transport</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">BP</td> <td class="col-xs-2"><a href="/go/view/5293" data-toggle="tooltip" data-placement="top" title=""The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]">GO:0006811</a></td> <td class="col-xs-6">ion transport</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">BP</td> <td class="col-xs-2"><a href="/go/view/5295" data-toggle="tooltip" data-placement="top" title=""The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]">GO:0006813</a></td> <td class="col-xs-6">potassium ion transport</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">BP</td> <td class="col-xs-2"><a href="/go/view/5341" data-toggle="tooltip" data-placement="top" title=""The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [ISBN:0198506732]">GO:0006869</a></td> <td class="col-xs-6">lipid transport</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/6094" data-toggle="tooltip" data-placement="top" title=""Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group." [EC:3.1.4.-, GOC:curators]">GO:0008081</a></td> <td class="col-xs-6">phosphoric diester hydrolase activity</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">BP</td> <td class="col-xs-2"><a href="/go/view/6154" data-toggle="tooltip" data-placement="top" title=""A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." [GOC:pdt]">GO:0008150</a></td> <td class="col-xs-6">biological_process</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">BP</td> <td class="col-xs-2"><a href="/go/view/7080" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue." [GOC:go_curators, ISBN:0198506732]">GO:0009187</a></td> <td class="col-xs-6">cyclic nucleotide metabolic process</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">BP</td> <td class="col-xs-2"><a href="/go/view/7083" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue." [GOC:go_curators, ISBN:0198506732]">GO:0009190</a></td> <td class="col-xs-6">cyclic nucleotide biosynthetic process</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">BP</td> <td class="col-xs-2"><a href="/go/view/7828" data-toggle="tooltip" data-placement="top" title=""Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators, GOC:isa_complete]">GO:0009987</a></td> <td class="col-xs-6">cellular process</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/9107" data-toggle="tooltip" data-placement="top" title=""Enables the transfer of an ion from one side of a membrane to the other." [GOC:dgf, GOC:mtg_transport, ISBN:0815340729]">GO:0015075</a></td> <td class="col-xs-6">ion transmembrane transporter activity</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/9272" data-toggle="tooltip" data-placement="top" title=""Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules." [GOC:mtg_transport, ISBN:0815340729, TC:1.-.-.-.-]">GO:0015267</a></td> <td class="col-xs-6">channel activity</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/9313" data-toggle="tooltip" data-placement="top" title=""Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon." [GOC:mtg_transport, ISBN:0815340729]">GO:0015318</a></td> <td class="col-xs-6">inorganic molecular entity transmembrane transporter activity</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">CC</td> <td class="col-xs-2"><a href="/go/view/9911" data-toggle="tooltip" data-placement="top" title=""A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it." [GOC:dos, GOC:mah, ISBN:0815316194]">GO:0016020</a></td> <td class="col-xs-6">membrane</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/10148" data-toggle="tooltip" data-placement="top" title=""Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [ISBN:0198506732]">GO:0016301</a></td> <td class="col-xs-6">kinase activity</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/10503" data-toggle="tooltip" data-placement="top" title=""Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [ISBN:0198506732]">GO:0016740</a></td> <td class="col-xs-6">transferase activity</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/10532" data-toggle="tooltip" data-placement="top" title=""Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732]">GO:0016772</a></td> <td class="col-xs-6">transferase activity, transferring phosphorus-containing groups</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/10533" data-toggle="tooltip" data-placement="top" title=""Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor)." [GOC:jl]">GO:0016773</a></td> <td class="col-xs-6">phosphotransferase activity, alcohol group as acceptor</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/10535" data-toggle="tooltip" data-placement="top" title=""Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenous group (acceptor)." [GOC:jl]">GO:0016775</a></td> <td class="col-xs-6">phosphotransferase activity, nitrogenous group as acceptor</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/10546" data-toggle="tooltip" data-placement="top" title=""Catalysis of the hydrolysis of any ester bond." [GOC:jl]">GO:0016788</a></td> <td class="col-xs-6">hydrolase activity, acting on ester bonds</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/13310" data-toggle="tooltip" data-placement="top" title=""Enables the transfer of a single solute from one side of a membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged." [GOC:mtg_transport, ISBN:0815340729]">GO:0022803</a></td> <td class="col-xs-6">passive transmembrane transporter activity</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/20569" data-toggle="tooltip" data-placement="top" title=""Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3." [GOC:jl]">GO:0042578</a></td> <td class="col-xs-6">phosphoric ester hydrolase activity</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">BP</td> <td class="col-xs-2"><a href="/go/view/27372" data-toggle="tooltip" data-placement="top" title=""Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation." [GOC:ai, GOC:dos]">GO:0051179</a></td> <td class="col-xs-6">localization</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">BP</td> <td class="col-xs-2"><a href="/go/view/27423" data-toggle="tooltip" data-placement="top" title=""Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." [GOC:ai, GOC:dos]">GO:0051234</a></td> <td class="col-xs-6">establishment of localization</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">BP</td> <td class="col-xs-2"><a href="/go/view/28990" data-toggle="tooltip" data-placement="top" title=""The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:dph, GOC:jid]">GO:0055085</a></td> <td class="col-xs-6">transmembrane transport</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">BP</td> <td class="col-xs-2"><a href="/go/view/30034" data-toggle="tooltip" data-placement="top" title=""A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." [GOC:dph, GOC:tb]">GO:0061024</a></td> <td class="col-xs-6">membrane organization</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">CC</td> <td class="col-xs-2"><a href="/go/view/38368" data-toggle="tooltip" data-placement="top" title=""A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." [GOC:kmv]">GO:0110165</a></td> <td class="col-xs-6">cellular anatomical entity</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">BP</td> <td class="col-xs-2"><a href="/go/view/38376" data-toggle="tooltip" data-placement="top" title=""The transport of lipids between membranes in which a lipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs)." [GOC:krc, PMID:20823909, PMID:24220498, PMID:25797198]">GO:0120009</a></td> <td class="col-xs-6">intermembrane lipid transfer</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/38730" data-toggle="tooltip" data-placement="top" title=""Catalytic activity that acts to modify a protein." [GOC:molecular_function_refactoring, GOC:pdt]">GO:0140096</a></td> <td class="col-xs-6">catalytic activity, acting on a protein</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> <tr style="clear:both;"> <td class="col-xs-1">MF</td> <td class="col-xs-2"><a href="/go/view/38853" data-toggle="tooltip" data-placement="top" title=""Binding to a small molecule and eliciting a change in the protein's activity in response to the intracellular level of that small molecule." [PMID:26328879]">GO:0140299</a></td> <td class="col-xs-6">small molecule sensor activity</td> <td class="col-xs-1">IEP</td> <td class="col-xs-2">Enrichment</td> </tr> </tbody> </table> </div> </div> <div class="tab-pane fade" id="tab3default"> <div class="panel-body"> <p>No InterPro domains available for this sequence</p> </div> </div> </div> </div> </div> <div class="row"> <div class="col-lg-12 col-md-12 col-sm-12"> <div class="panel panel-default"> <div class="panel-heading" id="links">External Links</div> <div class="table-responsive"> <table class="table table-striped table-separated"> <tbody> <tr> <td><em>No external refs found!</em></td> </td> </tr> </tbody> </table> </div> </div> </div> </div> <div class="modal" id="profileModal" tabindex="-1" role="dialog" aria-labelledby="profileModalLabel"> <div class="modal-dialog" role="document" style="width:1000px;height:800px;"> <div class="modal-content"> </div> </div> </div> </div> </div> </div> <footer class="footer" id="footer"> <div class="container"> <div class="row"> <div class="col-xs-2"><strong class="text-muted"><a href="/features" class="text-muted">protists.guru</a></strong></div> <div class="col-xs-2"><a href="/about" class="text-muted">About</a></div> <div class="col-xs-2"><a href="/contact" class="text-muted">Contact</a></div> <div class="col-xs-2"><a href="/disclaimer" class="text-muted">Disclaimer</a></div> <div class="col-xs-2"><a href="/privacy" class="text-muted">Privacy policy</a></div> </div> </div> </footer> <div class="modal" id="helpModal" tabindex="-1" role="dialog" aria-labelledby="helpModalLabel"> <div class="modal-dialog" role="document" style="width:1000px;height:800px;"> <div class="modal-content"> </div> </div> </div> <div class="modal" id="loaderModal" tabindex="-1" role="dialog" aria-labelledby="loaderModalLabel"> <div class="modal-dialog" role="document" style="width:1000px;height:800px;"> <div class="modal-content"> <div class="modal-body"> <div id="leafy_loader"></div> <p class="text-center text-muted" id="leafy_loader_text">Loading ... please wait ... </p> <p class="text-center" id="leafy_loader_close_btn" style="display:none"><button type="button" class="btn btn-primary" data-dismiss="modal" style>Close</button></p> </div> </div> </div> </div> <script src="/static/js/jquery.min.js"></script> <script src="/static/js/bootstrap.min.js"></script> <script src="/static/js/stupidtable.min.js"></script> <script src="/static/js/TweenMax.min.js"></script> <script src="/static/js/jquery.qtip.min.js"></script> <script src="/static/js/planet_loader.js"></script> <script>
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