lcl|LHPG02000025.1_cds_PRW20276.1_5743 (PRW20276)

Aliases : PRW20276

Description : DNA topoisomerase 3-alpha isoform X2

Gene families : OG_01_0001163 (OrthoFinder) Phylogenetic Tree(s): OG0001163_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: lcl\|LHPG02000025.1_cds_PRW20276.1_5743
Cluster	HCCA: Cluster_88

Target	Alias	Description	ECC score	Gene Family Method
PTI_01G08220.1	No alias	TOPRIM domain; DNA topoisomerase, type IA, central...	0.02	OrthoFinder
Vocar.0009s0242.1	32893315	Zinc finger, CCHC-type; TOPRIM domain; DNA...	0.02	OrthoFinder
XM_002499819.1	MICPUN_79030, 79030	DNA topoisomerase, type IA, central; TOPRIM domain...	0.02	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	IEA	Interproscan
MF	GO:0004672	protein kinase activity	None	Extended
MF	GO:0004674	protein serine/threonine kinase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006468	protein phosphorylation	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016301	kinase activity	None	Extended
BP	GO:0016310	phosphorylation	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0036211	protein modification process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000105	histidine biosynthetic process	IEP	Enrichment
BP	GO:0000154	rRNA modification	IEP	Enrichment
MF	GO:0000287	magnesium ion binding	IEP	Enrichment
BP	GO:0000350	generation of catalytic spliceosome for second transesterification step	IEP	Enrichment
BP	GO:0001510	RNA methylation	IEP	Enrichment
MF	GO:0003678	DNA helicase activity	IEP	Enrichment
MF	GO:0003682	chromatin binding	IEP	Enrichment
MF	GO:0003879	ATP phosphoribosyltransferase activity	IEP	Enrichment
MF	GO:0004826	phenylalanine-tRNA ligase activity	IEP	Enrichment
CC	GO:0005634	nucleus	IEP	Enrichment
BP	GO:0006338	chromatin remodeling	IEP	Enrichment
BP	GO:0006432	phenylalanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006547	histidine metabolic process	IEP	Enrichment
BP	GO:0006810	transport	IEP	Enrichment
BP	GO:0007034	vacuolar transport	IEP	Enrichment
MF	GO:0008649	rRNA methyltransferase activity	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009059	macromolecule biosynthetic process	IEP	Enrichment
MF	GO:0016435	rRNA (guanine) methyltransferase activity	IEP	Enrichment
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Enrichment
MF	GO:0016742	hydroxymethyl-, formyl- and related transferase activity	IEP	Enrichment
MF	GO:0016763	pentosyltransferase activity	IEP	Enrichment
BP	GO:0022618	ribonucleoprotein complex assembly	IEP	Enrichment
BP	GO:0031167	rRNA methylation	IEP	Enrichment
MF	GO:0031491	nucleosome binding	IEP	Enrichment
BP	GO:0032259	methylation	IEP	Enrichment
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0036265	RNA (guanine-N7)-methylation	IEP	Enrichment
BP	GO:0043044	ATP-dependent chromatin remodeling	IEP	Enrichment
CC	GO:0043226	organelle	IEP	Enrichment
CC	GO:0043227	membrane-bounded organelle	IEP	Enrichment
CC	GO:0043229	intracellular organelle	IEP	Enrichment
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Enrichment
BP	GO:0043414	macromolecule methylation	IEP	Enrichment
MF	GO:0044877	protein-containing complex binding	IEP	Enrichment
BP	GO:0051179	localization	IEP	Enrichment
BP	GO:0051234	establishment of localization	IEP	Enrichment
BP	GO:0070475	rRNA base methylation	IEP	Enrichment
BP	GO:0070476	rRNA (guanine-N7)-methylation	IEP	Enrichment
BP	GO:0071826	ribonucleoprotein complex subunit organization	IEP	Enrichment
CC	GO:0110165	cellular anatomical entity	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140102	catalytic activity, acting on a rRNA	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR006171	TOPRIM_domain	4	148
IPR013497	Topo_IA_cen	165	585
IPR004166	MHCK_EF2_kinase	917	1105

External Links

No external refs found!

lcl|LHPG02000025.1_cds_PRW20276.1_5743 (PRW20276)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation