lcl|LHPG02000002.1_cds_PRW60838.1_4785 (PRW60838)

Aliases : PRW60838

Description : 2-isopropylmalate synthase

Gene families : OG_01_0001203 (OrthoFinder) Phylogenetic Tree(s): OG0001203_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: lcl\|LHPG02000002.1_cds_PRW60838.1_4785
Cluster	HCCA: Cluster_51

Target	Alias	Description	ECC score	Gene Family Method
Cre06.g258733	30779056	2-isopropylmalate synthase A OS=Solanum pennellii	0.07	OrthoFinder
EOD26559	No alias	2-isopropylmalate synthase [Ensembl].	0.02	OrthoFinder
OT_01G05320.1	No alias	Pyruvate carboxyltransferase; 2-isopropylmalate synthase...	0.07	OrthoFinder
PTI_04G04840.1	No alias	2-isopropylmalate synthase LeuA, allosteric...	0.04	OrthoFinder
Sro178_g078170.1	Contig275.g3542	2-isopropylmalate synthase (Fragment)	0.04	OrthoFinder
Transcript_contig_53755	53755	Pyruvate carboxyltransferase; 2-isopropylmalate synthase...	0.02	OrthoFinder
XM_002508674.1	MICPUN_96632, 96632	2-isopropylmalate synthase	0.02	OrthoFinder
XM_003062964.1	MicpuC2_36068, 36068	2-isopropylmalate synthase	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	IEA	Interproscan
MF	GO:0003852	2-isopropylmalate synthase activity	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006551	leucine metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008652	cellular amino acid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009098	leucine biosynthetic process	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016053	organic acid biosynthetic process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016746	acyltransferase activity	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
BP	GO:0046394	carboxylic acid biosynthetic process	None	Extended
MF	GO:0046912	acyltransferase, acyl groups converted into alkyl on transfer	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000049	tRNA binding	IEP	Enrichment
BP	GO:0000105	histidine biosynthetic process	IEP	Enrichment
MF	GO:0000166	nucleotide binding	IEP	Enrichment
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Enrichment
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	Enrichment
MF	GO:0003924	GTPase activity	IEP	Enrichment
MF	GO:0004014	adenosylmethionine decarboxylase activity	IEP	Enrichment
MF	GO:0004359	glutaminase activity	IEP	Enrichment
MF	GO:0004399	histidinol dehydrogenase activity	IEP	Enrichment
MF	GO:0004455	ketol-acid reductoisomerase activity	IEP	Enrichment
MF	GO:0004527	exonuclease activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0004819	glutamine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004827	proline-tRNA ligase activity	IEP	Enrichment
MF	GO:0005488	binding	IEP	Enrichment
MF	GO:0005516	calmodulin binding	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
MF	GO:0005525	GTP binding	IEP	Enrichment
CC	GO:0005737	cytoplasm	IEP	Enrichment
BP	GO:0005991	trehalose metabolic process	IEP	Enrichment
BP	GO:0005992	trehalose biosynthetic process	IEP	Enrichment
BP	GO:0006081	cellular aldehyde metabolic process	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006351	transcription, DNA-templated	IEP	Enrichment
BP	GO:0006366	transcription by RNA polymerase II	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006425	glutaminyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006433	prolyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006536	glutamate metabolic process	IEP	Enrichment
BP	GO:0006537	glutamate biosynthetic process	IEP	Enrichment
BP	GO:0006547	histidine metabolic process	IEP	Enrichment
BP	GO:0006576	cellular biogenic amine metabolic process	IEP	Enrichment
BP	GO:0006595	polyamine metabolic process	IEP	Enrichment
BP	GO:0006596	polyamine biosynthetic process	IEP	Enrichment
BP	GO:0006597	spermine biosynthetic process	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0008215	spermine metabolic process	IEP	Enrichment
BP	GO:0008216	spermidine metabolic process	IEP	Enrichment
BP	GO:0008295	spermidine biosynthetic process	IEP	Enrichment
MF	GO:0008408	3'-5' exonuclease activity	IEP	Enrichment
MF	GO:0008987	quinolinate synthetase A activity	IEP	Enrichment
BP	GO:0009059	macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0009081	branched-chain amino acid metabolic process	IEP	Enrichment
BP	GO:0009082	branched-chain amino acid biosynthetic process	IEP	Enrichment
BP	GO:0009309	amine biosynthetic process	IEP	Enrichment
BP	GO:0009312	oligosaccharide biosynthetic process	IEP	Enrichment
BP	GO:0009435	NAD biosynthetic process	IEP	Enrichment
MF	GO:0015930	glutamate synthase activity	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
MF	GO:0016491	oxidoreductase activity	IEP	Enrichment
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Enrichment
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	IEP	Enrichment
MF	GO:0016779	nucleotidyltransferase activity	IEP	Enrichment
MF	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
MF	GO:0016887	ATPase	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
BP	GO:0018130	heterocycle biosynthetic process	IEP	Enrichment
MF	GO:0019001	guanyl nucleotide binding	IEP	Enrichment
BP	GO:0019359	nicotinamide nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0019362	pyridine nucleotide metabolic process	IEP	Enrichment
BP	GO:0019363	pyridine nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Enrichment
BP	GO:0032774	RNA biosynthetic process	IEP	Enrichment
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	Enrichment
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
BP	GO:0042401	cellular biogenic amine biosynthetic process	IEP	Enrichment
BP	GO:0042816	vitamin B6 metabolic process	IEP	Enrichment
BP	GO:0042819	vitamin B6 biosynthetic process	IEP	Enrichment
BP	GO:0042822	pyridoxal phosphate metabolic process	IEP	Enrichment
BP	GO:0042823	pyridoxal phosphate biosynthetic process	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0043648	dicarboxylic acid metabolic process	IEP	Enrichment
BP	GO:0043650	dicarboxylic acid biosynthetic process	IEP	Enrichment
BP	GO:0044106	cellular amine metabolic process	IEP	Enrichment
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:0046184	aldehyde biosynthetic process	IEP	Enrichment
BP	GO:0046351	disaccharide biosynthetic process	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
BP	GO:0046496	nicotinamide nucleotide metabolic process	IEP	Enrichment
MF	GO:0051539	4 iron, 4 sulfur cluster binding	IEP	Enrichment
BP	GO:0055114	obsolete oxidation-reduction process	IEP	Enrichment
BP	GO:0072524	pyridine-containing compound metabolic process	IEP	Enrichment
BP	GO:0072525	pyridine-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0097159	organic cyclic compound binding	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
BP	GO:0097659	nucleic acid-templated transcription	IEP	Enrichment
MF	GO:0097747	RNA polymerase activity	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment
MF	GO:1901363	heterocyclic compound binding	IEP	Enrichment
BP	GO:1901617	organic hydroxy compound biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR013709	2-isopropylmalate_synth_dimer	427	573
IPR000891	PYR_CT	48	326

External Links

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lcl|LHPG02000002.1_cds_PRW60838.1_4785 (PRW60838)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation