Vocar.0001s1108.1 (32885601)

Aliases : 32885601

Description : Calcineurin-like phosphoesterase domain, ApaH type; Mre11, DNA-binding [Interproscan].

Gene families : OG_01_0004553 (OrthoFinder) Phylogenetic Tree(s): OG0004553_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Vocar.0001s1108.1
Cluster	HCCA: Cluster_86

Target	Alias	Description	ECC score	Gene Family Method
Cpa\|evm.model.tig00000350.15	tig00000350_g24315.t1	DNA damage response.DNA repair mechanisms.homologous...	0.02	OrthoFinder
Dusal.0436s00004.1	33203582	Mre11, DNA-binding; Calcineurin-like phosphoesterase...	0.02	OrthoFinder
Sro557_g166210.1	Contig1427.g13191	Double-strand break repair protein MRE11	0.01	OrthoFinder
XM_002504568.1	MICPUN_61359, 61359	Mre11 DNA repair/recombination protein (MRE11)	0.02	OrthoFinder
XM_003063559.1	MicpuC2_70239, 70239	Mre11 DNA repair/recombination protein (MRE11)	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004519	endonuclease activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006302	double-strand break repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016787	hydrolase activity	IEA	Interproscan
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0030145	manganese ion binding	IEA	Interproscan
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000808	origin recognition complex	IEP	Enrichment
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003677	DNA binding	IEP	Enrichment
MF	GO:0003678	DNA helicase activity	IEP	Enrichment
MF	GO:0003916	DNA topoisomerase activity	IEP	Enrichment
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEP	Enrichment
MF	GO:0004470	malic enzyme activity	IEP	Enrichment
MF	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity	IEP	Enrichment
MF	GO:0004637	phosphoribosylamine-glycine ligase activity	IEP	Enrichment
CC	GO:0005643	nuclear pore	IEP	Enrichment
CC	GO:0005664	nuclear origin of replication recognition complex	IEP	Enrichment
CC	GO:0005730	nucleolus	IEP	Enrichment
BP	GO:0006144	purine nucleobase metabolic process	IEP	Enrichment
BP	GO:0006265	DNA topological change	IEP	Enrichment
BP	GO:0006298	mismatch repair	IEP	Enrichment
BP	GO:0006303	double-strand break repair via nonhomologous end joining	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
MF	GO:0008134	transcription factor binding	IEP	Enrichment
MF	GO:0008641	ubiquitin-like modifier activating enzyme activity	IEP	Enrichment
BP	GO:0009112	nucleobase metabolic process	IEP	Enrichment
BP	GO:0009113	purine nucleobase biosynthetic process	IEP	Enrichment
BP	GO:0009890	negative regulation of biosynthetic process	IEP	Enrichment
BP	GO:0009892	negative regulation of metabolic process	IEP	Enrichment
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0010605	negative regulation of macromolecule metabolic process	IEP	Enrichment
MF	GO:0016615	malate dehydrogenase activity	IEP	Enrichment
MF	GO:0016877	ligase activity, forming carbon-sulfur bonds	IEP	Enrichment
MF	GO:0030151	molybdenum ion binding	IEP	Enrichment
MF	GO:0030983	mismatched DNA binding	IEP	Enrichment
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	Enrichment
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
BP	GO:0042440	pigment metabolic process	IEP	Enrichment
BP	GO:0045892	negative regulation of transcription, DNA-templated	IEP	Enrichment
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0046112	nucleobase biosynthetic process	IEP	Enrichment
BP	GO:0046148	pigment biosynthetic process	IEP	Enrichment
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0051253	negative regulation of RNA metabolic process	IEP	Enrichment
BP	GO:0071103	DNA conformation change	IEP	Enrichment
MF	GO:0097159	organic cyclic compound binding	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment
CC	GO:0140513	nuclear protein-containing complex	IEP	Enrichment
MF	GO:1901363	heterocyclic compound binding	IEP	Enrichment
BP	GO:1902679	negative regulation of RNA biosynthetic process	IEP	Enrichment
BP	GO:1903507	negative regulation of nucleic acid-templated transcription	IEP	Enrichment
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR004843	Calcineurin-like_PHP_ApaH	12	256
IPR007281	Mre11_DNA-bd	303	484

External Links

No external refs found!

Vocar.0001s1108.1 (32885601)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation