Cpa|evm.model.tig00000237.42 (tig00000237_g20491.t1)

Aliases : tig00000237_g20491.t1

Description : Cell cycle.interphase.DNA replication.elongation.DNA polymerase alpha complex.POLA1 catalytic component

Gene families : OG_01_0002710 (OrthoFinder) Phylogenetic Tree(s): OG0002710_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Cpa\|evm.model.tig00000237.42
Cluster	HCCA: Cluster_49

Target	Alias	Description	ECC score	Gene Family Method
Cre04.g214350	30791491	Cell cycle.interphase.DNA replication.elongation.DNA...	0.1	OrthoFinder
Cz12g08090.t1	No alias	DNA-directed DNA polymerase, family B, multifunctional...	0.06	OrthoFinder
EOD27476	No alias	DNA polymerase alpha subunit 1 [Ensembl].	0.07	OrthoFinder
OT_08G00710.1	No alias	DNA polymerase alpha catalytic subunit, N-terminal...	0.06	OrthoFinder
PTI_00G03100.1	No alias	DNA-directed DNA polymerase, family B, exonuclease...	0.06	OrthoFinder
Sro49_g028720.1	Contig2054.g17622	DNA polymerase alpha catalytic subunit (Fragment)	0.1	OrthoFinder
Transcript_contig_54971	54971	DNA-directed DNA polymerase, family B, exonuclease...	0.05	OrthoFinder
Vocar.0025s0165.1	32898389	DNA-directed DNA polymerase, family B, multifunctional...	0.03	OrthoFinder
XM_002502979.1	MICPUN_59630, 59630	Zinc finger, DNA-directed DNA polymerase, family B,...	0.05	OrthoFinder
lcl\|BLLF01000259.1_cds_GFH09747.1_4224	HaLaN_04946, GFH09747	DNA polymerase	0.03	OrthoFinder
lcl\|BLLF01000259.1_cds_GFH09748.1_4225	HaLaN_04947, GFH09748	DNA-directed DNA polymerase, family B, exonuclease...	0.03	OrthoFinder
lcl\|BLLF01000259.1_cds_GFH09749.1_4226	HaLaN_04948, GFH09749	DNA polymerase	0.02	OrthoFinder
lcl\|VRMN01000019.1_cds_KAA8490764.1_6020	KAA8490764	DNA polymerase alpha catalytic subunit	0.05	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003887	DNA-directed DNA polymerase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006260	DNA replication	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016779	nucleotidyltransferase activity	None	Extended
MF	GO:0034061	DNA polymerase activity	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000151	ubiquitin ligase complex	IEP	Enrichment
CC	GO:0000152	nuclear ubiquitin ligase complex	IEP	Enrichment
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003677	DNA binding	IEP	Enrichment
MF	GO:0003690	double-stranded DNA binding	IEP	Enrichment
MF	GO:0003896	DNA primase activity	IEP	Enrichment
MF	GO:0003909	DNA ligase activity	IEP	Enrichment
MF	GO:0003910	DNA ligase (ATP) activity	IEP	Enrichment
MF	GO:0004797	thymidine kinase activity	IEP	Enrichment
MF	GO:0005515	protein binding	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
CC	GO:0005634	nucleus	IEP	Enrichment
CC	GO:0005680	anaphase-promoting complex	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006220	pyrimidine nucleotide metabolic process	IEP	Enrichment
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0006231	dTMP biosynthetic process	IEP	Enrichment
BP	GO:0006259	DNA metabolic process	IEP	Enrichment
BP	GO:0006270	DNA replication initiation	IEP	Enrichment
BP	GO:0006281	DNA repair	IEP	Enrichment
BP	GO:0006298	mismatch repair	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006950	response to stress	IEP	Enrichment
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Enrichment
BP	GO:0007346	regulation of mitotic cell cycle	IEP	Enrichment
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009124	nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009129	pyrimidine nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009162	deoxyribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009177	pyrimidine deoxyribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009219	pyrimidine deoxyribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009262	deoxyribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009263	deoxyribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009265	2'-deoxyribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009394	2'-deoxyribonucleotide metabolic process	IEP	Enrichment
BP	GO:0010564	regulation of cell cycle process	IEP	Enrichment
BP	GO:0010639	negative regulation of organelle organization	IEP	Enrichment
BP	GO:0010824	regulation of centrosome duplication	IEP	Enrichment
BP	GO:0010826	negative regulation of centrosome duplication	IEP	Enrichment
BP	GO:0010948	negative regulation of cell cycle process	IEP	Enrichment
BP	GO:0010965	regulation of mitotic sister chromatid separation	IEP	Enrichment
MF	GO:0016886	ligase activity, forming phosphoric ester bonds	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
MF	GO:0019136	deoxynucleoside kinase activity	IEP	Enrichment
MF	GO:0019205	nucleobase-containing compound kinase activity	IEP	Enrichment
MF	GO:0019206	nucleoside kinase activity	IEP	Enrichment
BP	GO:0019692	deoxyribose phosphate metabolic process	IEP	Enrichment
BP	GO:0030030	cell projection organization	IEP	Enrichment
BP	GO:0030031	cell projection assembly	IEP	Enrichment
BP	GO:0030071	regulation of mitotic metaphase/anaphase transition	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0030983	mismatched DNA binding	IEP	Enrichment
CC	GO:0031461	cullin-RING ubiquitin ligase complex	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
BP	GO:0032780	negative regulation of ATPase activity	IEP	Enrichment
BP	GO:0032886	regulation of microtubule-based process	IEP	Enrichment
BP	GO:0033043	regulation of organelle organization	IEP	Enrichment
BP	GO:0033044	regulation of chromosome organization	IEP	Enrichment
BP	GO:0033045	regulation of sister chromatid segregation	IEP	Enrichment
BP	GO:0033554	cellular response to stress	IEP	Enrichment
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
CC	GO:0036038	MKS complex	IEP	Enrichment
MF	GO:0042083	5,10-methylenetetrahydrofolate-dependent methyltransferase activity	IEP	Enrichment
CC	GO:0042555	MCM complex	IEP	Enrichment
BP	GO:0043086	negative regulation of catalytic activity	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
CC	GO:0043227	membrane-bounded organelle	IEP	Enrichment
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Enrichment
BP	GO:0043462	regulation of ATPase activity	IEP	Enrichment
BP	GO:0044092	negative regulation of molecular function	IEP	Enrichment
BP	GO:0044782	cilium organization	IEP	Enrichment
BP	GO:0045786	negative regulation of cell cycle	IEP	Enrichment
BP	GO:0046073	dTMP metabolic process	IEP	Enrichment
BP	GO:0046385	deoxyribose phosphate biosynthetic process	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
BP	GO:0046605	regulation of centrosome cycle	IEP	Enrichment
BP	GO:0046606	negative regulation of centrosome cycle	IEP	Enrichment
BP	GO:0048519	negative regulation of biological process	IEP	Enrichment
BP	GO:0048523	negative regulation of cellular process	IEP	Enrichment
BP	GO:0050790	regulation of catalytic activity	IEP	Enrichment
MF	GO:0050797	thymidylate synthase (FAD) activity	IEP	Enrichment
BP	GO:0050896	response to stimulus	IEP	Enrichment
BP	GO:0051095	regulation of helicase activity	IEP	Enrichment
BP	GO:0051097	negative regulation of helicase activity	IEP	Enrichment
BP	GO:0051128	regulation of cellular component organization	IEP	Enrichment
BP	GO:0051129	negative regulation of cellular component organization	IEP	Enrichment
BP	GO:0051493	regulation of cytoskeleton organization	IEP	Enrichment
BP	GO:0051494	negative regulation of cytoskeleton organization	IEP	Enrichment
BP	GO:0051716	cellular response to stimulus	IEP	Enrichment
BP	GO:0051726	regulation of cell cycle	IEP	Enrichment
BP	GO:0051983	regulation of chromosome segregation	IEP	Enrichment
BP	GO:0060271	cilium assembly	IEP	Enrichment
BP	GO:0065009	regulation of molecular function	IEP	Enrichment
BP	GO:0070925	organelle assembly	IEP	Enrichment
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Enrichment
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
BP	GO:0120031	plasma membrane bounded cell projection assembly	IEP	Enrichment
BP	GO:0120036	plasma membrane bounded cell projection organization	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment
BP	GO:1901987	regulation of cell cycle phase transition	IEP	Enrichment
BP	GO:1901990	regulation of mitotic cell cycle phase transition	IEP	Enrichment
BP	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	IEP	Enrichment
BP	GO:1905462	regulation of DNA duplex unwinding	IEP	Enrichment
BP	GO:1905463	negative regulation of DNA duplex unwinding	IEP	Enrichment
BP	GO:1905774	regulation of DNA helicase activity	IEP	Enrichment
BP	GO:1905775	negative regulation of DNA helicase activity	IEP	Enrichment
BP	GO:1905818	regulation of chromosome separation	IEP	Enrichment
BP	GO:2001251	negative regulation of chromosome organization	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR006133	DNA-dir_DNA_pol_B_exonuc	435	786
IPR015088	Znf_DNA-dir_DNA_pol_B_alpha	1438	1512
IPR024647	DNA_pol_a_cat_su_N	21	79
IPR006134	DNA-dir_DNA_pol_B_multi_dom	989	1299

External Links

No external refs found!

Cpa|evm.model.tig00000237.42 (tig00000237_g20491.t1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation