Sro1053_g235820.1 (Contig4118.g31453)

Aliases : Contig4118.g31453

Description : DNA topoisomerase 1

Gene families : OG_01_0002413 (OrthoFinder) Phylogenetic Tree(s): OG0002413_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Sro1053_g235820.1
Cluster	HCCA: Cluster_342

Target	Alias	Description	ECC score	Gene Family Method
Cre03.g178600	30787789, TOP1	Cell cycle.interphase.DNA replication.preinitiation.TOP1...	0.02	OrthoFinder
EOD31015	No alias	DNA topoisomerase type I [Ensembl].	0.02	OrthoFinder
PTI_11G01100.1	No alias	DNA topoisomerase I, DNA binding, eukaryotic-type;...	0.02	OrthoFinder
Sro3393_g347530.1	Contig655.g7779	DNA topoisomerase I, mitochondrial	0.01	OrthoFinder
lcl\|BLLF01002372.1_cds_GFH23824.1_18301	HaLaN_21508, GFH23824	DNA topoisomerase 1	0.03	OrthoFinder
lcl\|VRMN01000001.1_cds_KAA8499802.1_8755	KAA8499802	DNA topoisomerase 1 beta	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	None	Extended
MF	GO:0003917	DNA topoisomerase type I (single strand cut, ATP-independent) activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000295	adenine nucleotide transmembrane transporter activity	IEP	Enrichment
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	Enrichment
MF	GO:0004560	alpha-L-fucosidase activity	IEP	Enrichment
MF	GO:0004576	oligosaccharyl transferase activity	IEP	Enrichment
MF	GO:0004594	pantothenate kinase activity	IEP	Enrichment
MF	GO:0005048	signal sequence binding	IEP	Enrichment
MF	GO:0005092	GDP-dissociation inhibitor activity	IEP	Enrichment
MF	GO:0005346	purine ribonucleotide transmembrane transporter activity	IEP	Enrichment
MF	GO:0005347	ATP transmembrane transporter activity	IEP	Enrichment
MF	GO:0005471	ATP:ADP antiporter activity	IEP	Enrichment
MF	GO:0005515	protein binding	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
BP	GO:0006270	DNA replication initiation	IEP	Enrichment
BP	GO:0006284	base-excision repair	IEP	Enrichment
BP	GO:0006352	DNA-templated transcription, initiation	IEP	Enrichment
BP	GO:0006486	protein glycosylation	IEP	Enrichment
BP	GO:0006621	protein retention in ER lumen	IEP	Enrichment
BP	GO:0006810	transport	IEP	Enrichment
BP	GO:0006862	nucleotide transport	IEP	Enrichment
BP	GO:0006886	intracellular protein transport	IEP	Enrichment
BP	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IEP	Enrichment
BP	GO:0007021	tubulin complex assembly	IEP	Enrichment
BP	GO:0007023	post-chaperonin tubulin folding pathway	IEP	Enrichment
BP	GO:0007264	small GTPase mediated signal transduction	IEP	Enrichment
BP	GO:0008104	protein localization	IEP	Enrichment
MF	GO:0008514	organic anion transmembrane transporter activity	IEP	Enrichment
MF	GO:0008641	ubiquitin-like modifier activating enzyme activity	IEP	Enrichment
BP	GO:0009116	nucleoside metabolic process	IEP	Enrichment
BP	GO:0015031	protein transport	IEP	Enrichment
MF	GO:0015215	nucleotide transmembrane transporter activity	IEP	Enrichment
MF	GO:0015216	purine nucleotide transmembrane transporter activity	IEP	Enrichment
MF	GO:0015217	ADP transmembrane transporter activity	IEP	Enrichment
MF	GO:0015301	anion:anion antiporter activity	IEP	Enrichment
MF	GO:0015605	organophosphate ester transmembrane transporter activity	IEP	Enrichment
BP	GO:0015748	organophosphate ester transport	IEP	Enrichment
MF	GO:0015928	fucosidase activity	IEP	Enrichment
BP	GO:0015931	nucleobase-containing compound transport	IEP	Enrichment
MF	GO:0015932	nucleobase-containing compound transmembrane transporter activity	IEP	Enrichment
MF	GO:0016409	palmitoyltransferase activity	IEP	Enrichment
MF	GO:0016757	glycosyltransferase activity	IEP	Enrichment
MF	GO:0016758	hexosyltransferase activity	IEP	Enrichment
MF	GO:0016877	ligase activity, forming carbon-sulfur bonds	IEP	Enrichment
CC	GO:0030117	membrane coat	IEP	Enrichment
CC	GO:0030120	vesicle coat	IEP	Enrichment
CC	GO:0030127	COPII vesicle coat	IEP	Enrichment
MF	GO:0030234	enzyme regulator activity	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0030695	GTPase regulator activity	IEP	Enrichment
CC	GO:0030880	RNA polymerase complex	IEP	Enrichment
BP	GO:0032507	maintenance of protein location in cell	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
BP	GO:0032774	RNA biosynthetic process	IEP	Enrichment
BP	GO:0033036	macromolecule localization	IEP	Enrichment
MF	GO:0033218	amide binding	IEP	Enrichment
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	Enrichment
BP	GO:0035437	maintenance of protein localization in endoplasmic reticulum	IEP	Enrichment
MF	GO:0042277	peptide binding	IEP	Enrichment
BP	GO:0043413	macromolecule glycosylation	IEP	Enrichment
BP	GO:0045184	establishment of protein localization	IEP	Enrichment
BP	GO:0045185	maintenance of protein location	IEP	Enrichment
BP	GO:0046907	intracellular transport	IEP	Enrichment
MF	GO:0046923	ER retention sequence binding	IEP	Enrichment
BP	GO:0048193	Golgi vesicle transport	IEP	Enrichment
MF	GO:0048487	beta-tubulin binding	IEP	Enrichment
BP	GO:0051179	localization	IEP	Enrichment
BP	GO:0051234	establishment of localization	IEP	Enrichment
BP	GO:0051235	maintenance of location	IEP	Enrichment
BP	GO:0051641	cellular localization	IEP	Enrichment
BP	GO:0051649	establishment of localization in cell	IEP	Enrichment
BP	GO:0051651	maintenance of location in cell	IEP	Enrichment
MF	GO:0060589	nucleoside-triphosphatase regulator activity	IEP	Enrichment
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	Enrichment
BP	GO:0070085	glycosylation	IEP	Enrichment
BP	GO:0071702	organic substance transport	IEP	Enrichment
BP	GO:0071705	nitrogen compound transport	IEP	Enrichment
BP	GO:0072595	maintenance of protein localization in organelle	IEP	Enrichment
MF	GO:0097747	RNA polymerase activity	IEP	Enrichment
MF	GO:0098772	molecular function regulator	IEP	Enrichment
MF	GO:0140323	solute:anion antiporter activity	IEP	Enrichment
MF	GO:1901505	carbohydrate derivative transmembrane transporter activity	IEP	Enrichment
BP	GO:1901657	glycosyl compound metabolic process	IEP	Enrichment
CC	GO:1990234	transferase complex	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR013500	TopoI_cat_euk	318	564
IPR025834	TopoI_C_dom	659	726
IPR008336	TopoI_DNA-bd_euk	100	315

External Links

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Sro1053_g235820.1 (Contig4118.g31453)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation