lcl|VRMN01000005.1_cds_KAA8493992.1_3856 (KAA8493992)

Aliases : KAA8493992

Description : DNA topoisomerase 1

Gene families : OG_01_0003092 (OrthoFinder) Phylogenetic Tree(s): OG0003092_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: lcl\|VRMN01000005.1_cds_KAA8493992.1_3856
Cluster	HCCA: Cluster_42

Target	Alias	Description	ECC score	Gene Family Method	Actions
SymbC1.scaffold16.328	16.328	Topoisomerase C-terminal repeat; TOPRIM domain; DNA...	0.01	OrthoFinder
Vocar.0001s1224.1	32885891	High mobility group box domain; DNA topoisomerase, type...	0.01	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003684	damaged DNA binding	IEP	Enrichment
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Enrichment
MF	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity	IEP	Enrichment
MF	GO:0004842	ubiquitin-protein transferase activity	IEP	Enrichment
MF	GO:0005198	structural molecule activity	IEP	Enrichment
CC	GO:0005634	nucleus	IEP	Enrichment
CC	GO:0005643	nuclear pore	IEP	Enrichment
CC	GO:0005732	sno(s)RNA-containing ribonucleoprotein complex	IEP	Enrichment
BP	GO:0006260	DNA replication	IEP	Enrichment
BP	GO:0006281	DNA repair	IEP	Enrichment
BP	GO:0006333	chromatin assembly or disassembly	IEP	Enrichment
BP	GO:0006351	transcription, DNA-templated	IEP	Enrichment
BP	GO:0006352	DNA-templated transcription, initiation	IEP	Enrichment
BP	GO:0006364	rRNA processing	IEP	Enrichment
BP	GO:0006528	asparagine metabolic process	IEP	Enrichment
BP	GO:0006529	asparagine biosynthetic process	IEP	Enrichment
BP	GO:0006534	cysteine metabolic process	IEP	Enrichment
BP	GO:0006950	response to stress	IEP	Enrichment
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Enrichment
MF	GO:0008168	methyltransferase activity	IEP	Enrichment
MF	GO:0008171	O-methyltransferase activity	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009059	macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0009069	serine family amino acid metabolic process	IEP	Enrichment
BP	GO:0009092	homoserine metabolic process	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
BP	GO:0016072	rRNA metabolic process	IEP	Enrichment
MF	GO:0016740	transferase activity	IEP	Enrichment
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Enrichment
MF	GO:0016779	nucleotidyltransferase activity	IEP	Enrichment
MF	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	IEP	Enrichment
MF	GO:0017056	structural constituent of nuclear pore	IEP	Enrichment
BP	GO:0018130	heterocycle biosynthetic process	IEP	Enrichment
BP	GO:0019346	transsulfuration	IEP	Enrichment
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Enrichment
MF	GO:0019787	ubiquitin-like protein transferase activity	IEP	Enrichment
BP	GO:0032774	RNA biosynthetic process	IEP	Enrichment
BP	GO:0033554	cellular response to stress	IEP	Enrichment
MF	GO:0034061	DNA polymerase activity	IEP	Enrichment
CC	GO:0034457	Mpp10 complex	IEP	Enrichment
BP	GO:0034470	ncRNA processing	IEP	Enrichment
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0043138	3'-5' DNA helicase activity	IEP	Enrichment
CC	GO:0043226	organelle	IEP	Enrichment
CC	GO:0043227	membrane-bounded organelle	IEP	Enrichment
CC	GO:0043229	intracellular organelle	IEP	Enrichment
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Enrichment
MF	GO:0044877	protein-containing complex binding	IEP	Enrichment
BP	GO:0050667	homocysteine metabolic process	IEP	Enrichment
BP	GO:0051716	cellular response to stimulus	IEP	Enrichment
BP	GO:0097659	nucleic acid-templated transcription	IEP	Enrichment
CC	GO:0140513	nuclear protein-containing complex	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment
BP	GO:1901605	alpha-amino acid metabolic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR013497	Topo_IA_cen	141	574
IPR006171	TOPRIM_domain	3	126
IPR025589	Toprim_C_rpt	759	822
IPR025589	Toprim_C_rpt	894	941
IPR025589	Toprim_C_rpt	824	874

External Links

No external refs found!

lcl|VRMN01000005.1_cds_KAA8493992.1_3856 (KAA8493992)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation