EOD26100

Description : Alpha-adaptin [Ensembl].

Gene families : OG_01_0004160 (OrthoFinder) Phylogenetic Tree(s): OG0004160_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: EOD26100
Cluster	HCCA: Cluster_240

Target	Alias	Description	ECC score	Gene Family Method
Cre12.g488850	30793466, AP2A1	Vesicle trafficking.clathrin coated vesicle (CCV)...	0.04	OrthoFinder
Cz13g09020.t1	No alias	Clathrin adaptor, alpha-adaptin, appendage, C-terminal...	0.02	OrthoFinder
PTI_07G02900.1	No alias	Clathrin adaptor, alpha-adaptin, appendage, C-terminal...	0.02	OrthoFinder
Sro657_g182570.1	Contig301.g3977	AP-2 complex subunit alpha	0.01	OrthoFinder
XM_002502805.1	MICPUN_104856, 104856	Alpha-adaptin protein	0.01	OrthoFinder

Type	GO Term	Name	Evidence	Source
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
BP	GO:0006886	intracellular protein transport	IEA	Interproscan
BP	GO:0008104	protein localization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0015031	protein transport	None	Extended
BP	GO:0016192	vesicle-mediated transport	IEA	Interproscan
CC	GO:0030117	membrane coat	IEA	Interproscan
CC	GO:0030119	AP-type membrane coat adaptor complex	None	Extended
CC	GO:0030131	clathrin adaptor complex	IEA	Interproscan
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0033036	macromolecule localization	None	Extended
BP	GO:0045184	establishment of protein localization	None	Extended
BP	GO:0046907	intracellular transport	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0051641	cellular localization	None	Extended
BP	GO:0051649	establishment of localization in cell	None	Extended
BP	GO:0071702	organic substance transport	None	Extended
BP	GO:0071705	nitrogen compound transport	None	Extended
CC	GO:0098796	membrane protein complex	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	IEP	Enrichment
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	Enrichment
MF	GO:0004312	fatty acid synthase activity	IEP	Enrichment
MF	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity	IEP	Enrichment
MF	GO:0004402	histone acetyltransferase activity	IEP	Enrichment
MF	GO:0004672	protein kinase activity	IEP	Enrichment
MF	GO:0005048	signal sequence binding	IEP	Enrichment
MF	GO:0005488	binding	IEP	Enrichment
MF	GO:0005515	protein binding	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
CC	GO:0005634	nucleus	IEP	Enrichment
CC	GO:0005667	transcription regulator complex	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006325	chromatin organization	IEP	Enrichment
BP	GO:0006334	nucleosome assembly	IEP	Enrichment
BP	GO:0006351	transcription, DNA-templated	IEP	Enrichment
BP	GO:0006355	regulation of transcription, DNA-templated	IEP	Enrichment
BP	GO:0006464	cellular protein modification process	IEP	Enrichment
BP	GO:0006468	protein phosphorylation	IEP	Enrichment
BP	GO:0006473	protein acetylation	IEP	Enrichment
BP	GO:0006475	internal protein amino acid acetylation	IEP	Enrichment
BP	GO:0006621	protein retention in ER lumen	IEP	Enrichment
BP	GO:0006631	fatty acid metabolic process	IEP	Enrichment
BP	GO:0006633	fatty acid biosynthetic process	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006807	nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0006904	vesicle docking involved in exocytosis	IEP	Enrichment
BP	GO:0008152	metabolic process	IEP	Enrichment
MF	GO:0008408	3'-5' exonuclease activity	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009059	macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0009889	regulation of biosynthetic process	IEP	Enrichment
BP	GO:0010468	regulation of gene expression	IEP	Enrichment
BP	GO:0010556	regulation of macromolecule biosynthetic process	IEP	Enrichment
MF	GO:0015035	protein-disulfide reductase activity	IEP	Enrichment
MF	GO:0015036	disulfide oxidoreductase activity	IEP	Enrichment
BP	GO:0016043	cellular component organization	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
MF	GO:0016301	kinase activity	IEP	Enrichment
BP	GO:0016310	phosphorylation	IEP	Enrichment
BP	GO:0016569	covalent chromatin modification	IEP	Enrichment
BP	GO:0016570	histone modification	IEP	Enrichment
BP	GO:0016573	histone acetylation	IEP	Enrichment
MF	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	IEP	Enrichment
MF	GO:0016740	transferase activity	IEP	Enrichment
MF	GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	IEP	Enrichment
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Enrichment
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEP	Enrichment
MF	GO:0016779	nucleotidyltransferase activity	IEP	Enrichment
BP	GO:0018130	heterocycle biosynthetic process	IEP	Enrichment
BP	GO:0018205	peptidyl-lysine modification	IEP	Enrichment
BP	GO:0018393	internal peptidyl-lysine acetylation	IEP	Enrichment
BP	GO:0018394	peptidyl-lysine acetylation	IEP	Enrichment
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0019222	regulation of metabolic process	IEP	Enrichment
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Enrichment
BP	GO:0019748	secondary metabolic process	IEP	Enrichment
BP	GO:0022406	membrane docking	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
BP	GO:0030638	polyketide metabolic process	IEP	Enrichment
BP	GO:0031323	regulation of cellular metabolic process	IEP	Enrichment
BP	GO:0031326	regulation of cellular biosynthetic process	IEP	Enrichment
BP	GO:0032507	maintenance of protein location in cell	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
BP	GO:0032774	RNA biosynthetic process	IEP	Enrichment
MF	GO:0033218	amide binding	IEP	Enrichment
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	Enrichment
MF	GO:0034212	peptide N-acetyltransferase activity	IEP	Enrichment
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0034728	nucleosome organization	IEP	Enrichment
BP	GO:0035437	maintenance of protein localization in endoplasmic reticulum	IEP	Enrichment
BP	GO:0036211	protein modification process	IEP	Enrichment
MF	GO:0042277	peptide binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0043170	macromolecule metabolic process	IEP	Enrichment
CC	GO:0043227	membrane-bounded organelle	IEP	Enrichment
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Enrichment
BP	GO:0043543	protein acylation	IEP	Enrichment
BP	GO:0044237	cellular metabolic process	IEP	Enrichment
BP	GO:0044238	primary metabolic process	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Enrichment
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:0045185	maintenance of protein location	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
MF	GO:0046923	ER retention sequence binding	IEP	Enrichment
MF	GO:0046983	protein dimerization activity	IEP	Enrichment
BP	GO:0048278	vesicle docking	IEP	Enrichment
BP	GO:0050789	regulation of biological process	IEP	Enrichment
BP	GO:0050794	regulation of cellular process	IEP	Enrichment
BP	GO:0051171	regulation of nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0051235	maintenance of location	IEP	Enrichment
BP	GO:0051252	regulation of RNA metabolic process	IEP	Enrichment
BP	GO:0051640	organelle localization	IEP	Enrichment
BP	GO:0051651	maintenance of location in cell	IEP	Enrichment
BP	GO:0060255	regulation of macromolecule metabolic process	IEP	Enrichment
MF	GO:0061733	peptide-lysine-N-acetyltransferase activity	IEP	Enrichment
BP	GO:0065004	protein-DNA complex assembly	IEP	Enrichment
BP	GO:0065007	biological regulation	IEP	Enrichment
BP	GO:0071704	organic substance metabolic process	IEP	Enrichment
BP	GO:0071824	protein-DNA complex subunit organization	IEP	Enrichment
BP	GO:0071840	cellular component organization or biogenesis	IEP	Enrichment
BP	GO:0072330	monocarboxylic acid biosynthetic process	IEP	Enrichment
BP	GO:0072595	maintenance of protein localization in organelle	IEP	Enrichment
BP	GO:0080090	regulation of primary metabolic process	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
MF	GO:0097159	organic cyclic compound binding	IEP	Enrichment
BP	GO:0097659	nucleic acid-templated transcription	IEP	Enrichment
MF	GO:0097747	RNA polymerase activity	IEP	Enrichment
BP	GO:0140029	exocytic process	IEP	Enrichment
BP	GO:0140056	organelle localization by membrane tethering	IEP	Enrichment
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment
MF	GO:1901363	heterocyclic compound binding	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment
BP	GO:1903506	regulation of nucleic acid-templated transcription	IEP	Enrichment
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	IEP	Enrichment
BP	GO:2001141	regulation of RNA biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR002553	Clathrin/coatomer_adapt-like_N	20	574
IPR008152	Clathrin_a/b/g-adaptin_app_Ig	753	845
IPR003164	Clathrin_a-adaptin_app_sub_C	861	973

External Links

No external refs found!

EOD26100

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation