EOD06573

Description : DNA polymerase epsilon catalytic subunit A/1 [Ensembl].

Gene families : OG_01_0002052 (OrthoFinder) Phylogenetic Tree(s): OG0002052_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: EOD06573
Cluster	HCCA: Cluster_116

Target	Alias	Description	ECC score	Gene Family Method
Cpa\|evm.model.tig00000970.30	tig00000970_g5849.t1	Cell cycle.interphase.DNA replication.elongation.DNA...	0.04	OrthoFinder
Cpa\|evm.model.tig00000970.31	tig00000970_g5849.t1	DNA polymerase epsilon catalytic subunit A...	0.04	OrthoFinder
Cre03.g179961	30788184	Cell cycle.interphase.DNA replication.elongation.DNA...	0.07	OrthoFinder
Cz01g29080.t1	No alias	DNA-directed DNA polymerase, family B, multifunctional...	0.03	OrthoFinder
Dusal.0146s00025.1	33199498	DNA-directed DNA polymerase, family B, multifunctional...	0.05	OrthoFinder
OT_11G01900.1	No alias	DNA-directed DNA polymerase, family B, multifunctional...	0.09	OrthoFinder
PTI_27G01310.1	No alias	DNA-directed DNA polymerase, family B, multifunctional...	0.07	OrthoFinder
Sro1830_g300310.1	Contig662.g7834	Epsilon catalytic subunit A	0.01	OrthoFinder
TP03G08210.1	No alias	DNA-directed DNA polymerase, family B, exonuclease...	0.03	OrthoFinder
Transcript_contig_613	613	DNA-directed DNA polymerase, family B, exonuclease...	0.04	OrthoFinder
XM_002508999.1	MICPUN_63095, 63095	DNA polymerase epsilon, catalytic subunit A, C-terminal;...	0.08	OrthoFinder
XM_003061673.1	MicpuC2_51203, 51203	DNA-directed DNA polymerase, family B, multifunctional...	0.03	OrthoFinder
lcl\|VRMN01000001.1_cds_KAA8497716.1_6669	KAA8497716	DNA polymerase epsilon catalytic subunit A	0.01	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003887	DNA-directed DNA polymerase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IEA	Interproscan
BP	GO:0006260	DNA replication	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008270	zinc ion binding	IEA	Interproscan
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016779	nucleotidyltransferase activity	None	Extended
MF	GO:0034061	DNA polymerase activity	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
CC	GO:0000808	origin recognition complex	IEP	Enrichment
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003677	DNA binding	IEP	Enrichment
MF	GO:0003689	DNA clamp loader activity	IEP	Enrichment
MF	GO:0003690	double-stranded DNA binding	IEP	Enrichment
MF	GO:0003852	2-isopropylmalate synthase activity	IEP	Enrichment
MF	GO:0003896	DNA primase activity	IEP	Enrichment
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	Enrichment
MF	GO:0003909	DNA ligase activity	IEP	Enrichment
MF	GO:0003910	DNA ligase (ATP) activity	IEP	Enrichment
MF	GO:0004345	glucose-6-phosphate dehydrogenase activity	IEP	Enrichment
MF	GO:0004518	nuclease activity	IEP	Enrichment
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
CC	GO:0005663	DNA replication factor C complex	IEP	Enrichment
BP	GO:0006006	glucose metabolic process	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006259	DNA metabolic process	IEP	Enrichment
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	Enrichment
BP	GO:0006270	DNA replication initiation	IEP	Enrichment
BP	GO:0006281	DNA repair	IEP	Enrichment
BP	GO:0006298	mismatch repair	IEP	Enrichment
BP	GO:0006310	DNA recombination	IEP	Enrichment
BP	GO:0006551	leucine metabolic process	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006807	nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0006950	response to stress	IEP	Enrichment
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Enrichment
BP	GO:0009098	leucine biosynthetic process	IEP	Enrichment
MF	GO:0016597	amino acid binding	IEP	Enrichment
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	IEP	Enrichment
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	IEP	Enrichment
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Enrichment
MF	GO:0016743	carboxyl- or carbamoyltransferase activity	IEP	Enrichment
MF	GO:0016886	ligase activity, forming phosphoric ester bonds	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
BP	GO:0018130	heterocycle biosynthetic process	IEP	Enrichment
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0030983	mismatched DNA binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
BP	GO:0032774	RNA biosynthetic process	IEP	Enrichment
BP	GO:0033554	cellular response to stress	IEP	Enrichment
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	Enrichment
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
MF	GO:0043177	organic acid binding	IEP	Enrichment
BP	GO:0044238	primary metabolic process	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
MF	GO:0046912	acyltransferase, acyl groups converted into alkyl on transfer	IEP	Enrichment
BP	GO:0050896	response to stimulus	IEP	Enrichment
BP	GO:0051716	cellular response to stimulus	IEP	Enrichment
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
MF	GO:0097159	organic cyclic compound binding	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
MF	GO:0097747	RNA polymerase activity	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment
MF	GO:1901363	heterocyclic compound binding	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR006133	DNA-dir_DNA_pol_B_exonuc	185	242
IPR013697	DNA_pol_e_suA_C	1000	1147
IPR013697	DNA_pol_e_suA_C	1264	1382

External Links

No external refs found!

EOD06573

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation