Dusal.0007s00039.1 (33201185)

Aliases : 33201185

Description : DNA topoisomerase I, catalytic core, eukaryotic-type; Topoisomerase I C-terminal domain; DNA topoisomerase I, DNA binding, eukaryotic-type [Interproscan].

Gene families : OG_01_0002413 (OrthoFinder) Phylogenetic Tree(s): OG0002413_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Dusal.0007s00039.1
Cluster	HCCA: Cluster_95

Target	Alias	Description	ECC score	Gene Family Method
Cre03.g178600	30787789, TOP1	Cell cycle.interphase.DNA replication.preinitiation.TOP1...	0.02	OrthoFinder
EOD31015	No alias	DNA topoisomerase type I [Ensembl].	0.03	OrthoFinder
SymbC1.scaffold143.2	143.2	Topoisomerase I C-terminal domain; DNA topoisomerase I,...	0.02	OrthoFinder
lcl\|BLLF01002372.1_cds_GFH23824.1_18301	HaLaN_21508, GFH23824	DNA topoisomerase 1	0.02	OrthoFinder
lcl\|LHPG02000023.1_cds_PRW20584.1_5407	PRW20584	DNA topoisomerase 1-like	0.02	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	None	Extended
MF	GO:0003917	DNA topoisomerase type I (single strand cut, ATP-independent) activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000030	mannosyltransferase activity	IEP	Enrichment
CC	GO:0000148	1,3-beta-D-glucan synthase complex	IEP	Enrichment
MF	GO:0000166	nucleotide binding	IEP	Enrichment
BP	GO:0000271	polysaccharide biosynthetic process	IEP	Enrichment
BP	GO:0001510	RNA methylation	IEP	Enrichment
MF	GO:0003684	damaged DNA binding	IEP	Enrichment
MF	GO:0003843	1,3-beta-D-glucan synthase activity	IEP	Enrichment
MF	GO:0004376	glycolipid mannosyltransferase activity	IEP	Enrichment
MF	GO:0004386	helicase activity	IEP	Enrichment
MF	GO:0005049	nuclear export signal receptor activity	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
BP	GO:0005976	polysaccharide metabolic process	IEP	Enrichment
BP	GO:0006073	cellular glucan metabolic process	IEP	Enrichment
BP	GO:0006074	(1->3)-beta-D-glucan metabolic process	IEP	Enrichment
BP	GO:0006075	(1->3)-beta-D-glucan biosynthetic process	IEP	Enrichment
BP	GO:0006289	nucleotide-excision repair	IEP	Enrichment
BP	GO:0006367	transcription initiation from RNA polymerase II promoter	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006497	protein lipidation	IEP	Enrichment
BP	GO:0006505	GPI anchor metabolic process	IEP	Enrichment
BP	GO:0006506	GPI anchor biosynthetic process	IEP	Enrichment
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Enrichment
BP	GO:0006606	protein import into nucleus	IEP	Enrichment
BP	GO:0006661	phosphatidylinositol biosynthetic process	IEP	Enrichment
BP	GO:0006810	transport	IEP	Enrichment
BP	GO:0006886	intracellular protein transport	IEP	Enrichment
BP	GO:0006904	vesicle docking involved in exocytosis	IEP	Enrichment
BP	GO:0006913	nucleocytoplasmic transport	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
BP	GO:0008104	protein localization	IEP	Enrichment
MF	GO:0008146	sulfotransferase activity	IEP	Enrichment
MF	GO:0008194	UDP-glycosyltransferase activity	IEP	Enrichment
MF	GO:0008641	ubiquitin-like modifier activating enzyme activity	IEP	Enrichment
BP	GO:0009057	macromolecule catabolic process	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009059	macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0009250	glucan biosynthetic process	IEP	Enrichment
BP	GO:0010498	proteasomal protein catabolic process	IEP	Enrichment
BP	GO:0015031	protein transport	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
MF	GO:0016757	glycosyltransferase activity	IEP	Enrichment
MF	GO:0016758	hexosyltransferase activity	IEP	Enrichment
MF	GO:0016782	transferase activity, transferring sulphur-containing groups	IEP	Enrichment
MF	GO:0016877	ligase activity, forming carbon-sulfur bonds	IEP	Enrichment
MF	GO:0016887	ATPase	IEP	Enrichment
BP	GO:0017038	protein import	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
MF	GO:0019899	enzyme binding	IEP	Enrichment
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Enrichment
BP	GO:0022406	membrane docking	IEP	Enrichment
BP	GO:0030163	protein catabolic process	IEP	Enrichment
BP	GO:0030488	tRNA methylation	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
CC	GO:0031515	tRNA (m1A) methyltransferase complex	IEP	Enrichment
MF	GO:0031625	ubiquitin protein ligase binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
BP	GO:0032774	RNA biosynthetic process	IEP	Enrichment
BP	GO:0033036	macromolecule localization	IEP	Enrichment
BP	GO:0033692	cellular polysaccharide biosynthetic process	IEP	Enrichment
BP	GO:0034504	protein localization to nucleus	IEP	Enrichment
BP	GO:0034637	cellular carbohydrate biosynthetic process	IEP	Enrichment
CC	GO:0034708	methyltransferase complex	IEP	Enrichment
MF	GO:0035251	UDP-glucosyltransferase activity	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0043414	macromolecule methylation	IEP	Enrichment
CC	GO:0043527	tRNA methyltransferase complex	IEP	Enrichment
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Enrichment
BP	GO:0044042	glucan metabolic process	IEP	Enrichment
BP	GO:0044248	cellular catabolic process	IEP	Enrichment
BP	GO:0044264	cellular polysaccharide metabolic process	IEP	Enrichment
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Enrichment
MF	GO:0044389	ubiquitin-like protein ligase binding	IEP	Enrichment
BP	GO:0045184	establishment of protein localization	IEP	Enrichment
MF	GO:0046527	glucosyltransferase activity	IEP	Enrichment
BP	GO:0046907	intracellular transport	IEP	Enrichment
BP	GO:0048278	vesicle docking	IEP	Enrichment
BP	GO:0051169	nuclear transport	IEP	Enrichment
BP	GO:0051170	import into nucleus	IEP	Enrichment
BP	GO:0051179	localization	IEP	Enrichment
BP	GO:0051234	establishment of localization	IEP	Enrichment
BP	GO:0051273	beta-glucan metabolic process	IEP	Enrichment
BP	GO:0051274	beta-glucan biosynthetic process	IEP	Enrichment
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Enrichment
BP	GO:0051640	organelle localization	IEP	Enrichment
BP	GO:0051641	cellular localization	IEP	Enrichment
BP	GO:0051649	establishment of localization in cell	IEP	Enrichment
MF	GO:0051751	alpha-1,4-mannosyltransferase activity	IEP	Enrichment
MF	GO:0061608	nuclear import signal receptor activity	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
CC	GO:0098797	plasma membrane protein complex	IEP	Enrichment
BP	GO:0140029	exocytic process	IEP	Enrichment
BP	GO:0140056	organelle localization by membrane tethering	IEP	Enrichment
MF	GO:0140104	molecular carrier activity	IEP	Enrichment
MF	GO:0140142	nucleocytoplasmic carrier activity	IEP	Enrichment
MF	GO:0140597	protein carrier activity	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
BP	GO:1901565	organonitrogen compound catabolic process	IEP	Enrichment
CC	GO:1990234	transferase complex	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR008336	TopoI_DNA-bd_euk	143	210
IPR008336	TopoI_DNA-bd_euk	215	299
IPR025834	TopoI_C_dom	511	580
IPR013500	TopoI_cat_euk	328	488

External Links

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Dusal.0007s00039.1 (33201185)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation