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(Values are log2 transformed ratios of a genes expression in a sample divided by the mean expression level)
Gene | OTH95 | RCC4221 | RCC745,25uM Cu,1h | RCC745,25uM Cu,4h | RCC745,25uM Cu,12h | RCC745,250uM Cu,1h | RCC745,250uM Cu,4h | RCC745,250uM Cu,12h | RCC745,Control,0h | RCC745,Control,1h | RCC745,Control,4h | RCC745,Control,12h |
---|---|---|---|---|---|---|---|---|---|---|---|---|
0.95 | 1.39 | -1.77 | -0.24 | -0.89 | -0.13 | -1.27 | -0.4 | -1.4 | 0.85 | -0.92 | -0.02 | |
-0.05 | 0.33 | -0.24 | -0.25 | 0.17 | -0.07 | 0.03 | 0.07 | -0.19 | -0.14 | 0.0 | 0.21 | |
-0.2 | 0.42 | -0.63 | -0.0 | 0.16 | -0.12 | 0.25 | -0.26 | -0.27 | 0.11 | -0.13 | 0.33 | |
0.64 | 0.97 | -0.14 | -0.67 | -0.2 | -0.42 | -0.78 | -0.32 | -0.51 | 0.78 | -0.2 | -0.62 | |
-0.34 | 0.49 | -0.12 | -0.11 | -0.26 | -0.02 | -0.01 | -0.69 | -0.17 | 0.65 | -0.01 | 0.1 | |
0.01 | 0.11 | -0.18 | -0.07 | -0.07 | -0.0 | 0.08 | -0.31 | -0.24 | 0.42 | 0.11 | 0.01 | |
-0.06 | 0.19 | -0.01 | -0.1 | 0.01 | -0.11 | -0.21 | -0.05 | -0.26 | 0.46 | 0.12 | -0.13 | |
0.48 | 1.04 | 0.25 | -0.57 | -0.74 | -0.39 | -1.31 | -0.66 | -0.51 | 0.94 | -0.08 | -0.49 | |
0.88 | 0.89 | -0.06 | -0.33 | -0.77 | -0.39 | -0.63 | -0.76 | -0.72 | 0.68 | -0.4 | -0.0 | |
0.6 | 0.83 | -0.63 | -0.67 | 0.3 | -0.29 | -0.62 | -0.15 | -0.53 | 0.4 | 0.04 | -0.34 | |
0.38 | 1.24 | 0.07 | -0.9 | -0.58 | -0.8 | -1.92 | -0.65 | -0.93 | 1.24 | 0.04 | -0.52 | |
1.57 | 2.05 | -1.14 | -1.8 | -1.9 | -1.73 | -1.9 | -2.42 | -1.85 | 0.95 | -1.46 | -0.82 | |
-0.0 | 0.46 | -0.01 | -0.14 | -0.4 | -0.23 | -0.28 | -0.31 | -0.14 | 0.63 | 0.11 | -0.09 | |
1.52 | 1.26 | -1.13 | -1.56 | -0.28 | -0.42 | -1.19 | 0.08 | -0.53 | -0.06 | -0.45 | -1.01 | |
2.16 | 2.69 | -3.1 | -3.91 | -3.84 | -4.05 | -5.94 | -4.26 | -4.19 | -0.92 | -3.28 | -5.55 | |
0.54 | 1.31 | -0.66 | -0.51 | -0.18 | -0.47 | -0.6 | -0.76 | -0.74 | 0.59 | -0.15 | -0.19 | |
1.76 | 2.09 | -0.69 | -1.65 | -1.58 | -1.81 | -2.79 | -2.08 | -1.95 | 0.4 | -1.02 | -1.51 | |
0.18 | 0.17 | -0.32 | -0.23 | 0.13 | -0.33 | 0.09 | 0.07 | -0.18 | 0.06 | 0.04 | 0.18 | |
0.49 | 0.79 | -0.21 | -0.07 | -0.44 | -0.22 | -0.47 | -0.61 | -0.31 | 0.56 | -0.2 | -0.12 | |
2.24 | 2.18 | -3.13 | -1.72 | -2.35 | -2.0 | -3.05 | -2.05 | -3.31 | 0.35 | - | -2.76 | |
0.41 | 0.73 | -0.36 | -0.42 | -0.13 | -0.05 | -0.32 | -0.57 | -0.55 | 0.68 | -0.1 | -0.12 | |
0.35 | 0.51 | -0.56 | -0.17 | 0.2 | -0.22 | -0.09 | -0.0 | -0.14 | -0.14 | -0.04 | -0.01 | |
0.89 | 1.74 | -0.28 | -1.31 | -1.16 | -1.0 | -2.41 | -0.87 | -1.68 | 1.23 | -0.41 | -1.05 | |
0.59 | 0.74 | -0.17 | -0.58 | -0.07 | -0.5 | -0.29 | -0.2 | -0.56 | 0.49 | -0.12 | -0.12 | |
1.02 | 1.28 | -0.56 | -1.07 | -0.33 | -0.42 | -1.46 | -0.13 | -0.63 | 0.37 | -0.16 | -0.44 | |
0.5 | 0.87 | -0.1 | -0.4 | -0.19 | -0.35 | -0.73 | -0.14 | -0.42 | 0.49 | -0.06 | -0.35 | |
0.88 | 1.23 | -0.26 | -0.9 | -0.21 | -0.43 | -1.27 | -0.48 | -0.7 | 0.57 | -0.15 | -0.51 | |
-0.16 | 1.26 | -0.68 | -0.57 | -0.07 | -0.39 | -0.26 | -0.41 | -0.59 | 0.84 | -0.22 | -0.33 | |
0.27 | 1.1 | -0.43 | -0.49 | -0.68 | -0.57 | -0.5 | -0.7 | -1.05 | 1.22 | -0.29 | -0.07 | |
0.59 | 1.76 | -0.37 | -1.23 | -0.5 | -1.17 | -1.19 | -1.42 | -1.69 | 1.08 | -0.3 | -0.5 | |
-0.04 | 0.24 | -0.35 | -0.31 | 0.03 | -0.18 | 0.09 | -0.16 | -0.3 | 0.49 | 0.07 | 0.17 | |
0.45 | 0.93 | -0.54 | -0.28 | 0.16 | -0.52 | -0.19 | 0.04 | -0.26 | 0.03 | -0.25 | -0.32 | |
-0.27 | -0.06 | -0.07 | 0.11 | 0.01 | -0.1 | 0.07 | -0.09 | 0.04 | 0.09 | 0.2 | 0.0 | |
0.04 | 0.74 | -0.26 | -0.17 | -0.16 | -0.25 | 0.12 | -0.54 | -0.35 | 0.45 | -0.25 | 0.1 | |
0.62 | 0.99 | -0.23 | -0.77 | -0.41 | -0.42 | -0.83 | -0.72 | -0.51 | 0.93 | 0.04 | -0.44 | |
-0.14 | 0.41 | -0.41 | -0.18 | 0.27 | -0.12 | 0.07 | 0.03 | -0.09 | -0.41 | 0.18 | 0.17 | |
2.01 | 1.71 | -1.27 | -1.55 | -0.77 | -1.42 | -1.72 | -1.53 | -1.99 | 0.15 | -1.05 | -1.06 | |
2.4 | 2.03 | -2.49 | -2.95 | -3.22 | -4.75 | -2.62 | -2.56 | - | 0.54 | -2.19 | -2.49 | |
0.78 | 1.22 | -0.92 | -0.58 | -0.55 | -0.39 | -0.71 | -0.31 | -0.91 | 0.72 | -0.13 | -0.33 | |
0.43 | 1.13 | -0.68 | -0.54 | -0.21 | -0.35 | -0.61 | -0.77 | -0.65 | 0.82 | -0.25 | 0.03 | |
-0.13 | 0.43 | -0.09 | 0.03 | -0.12 | -0.54 | 0.19 | -0.17 | -0.11 | 0.38 | -0.08 | -0.04 | |
-0.31 | 1.11 | -0.44 | -0.07 | 0.07 | -0.48 | -0.12 | -0.14 | -0.15 | -0.01 | -0.16 | -0.07 | |
0.46 | 0.91 | -0.15 | -0.52 | -0.33 | -0.38 | -0.94 | -0.26 | -0.69 | 0.92 | -0.01 | -0.45 | |
0.57 | 0.5 | -0.56 | -0.24 | -0.03 | -0.22 | -0.25 | -0.1 | -0.6 | 0.26 | -0.07 | 0.2 | |
0.79 | 1.74 | -0.46 | -0.45 | -0.71 | -0.97 | -0.7 | -0.72 | -0.79 | 0.1 | -0.51 | -0.38 | |
0.32 | 1.27 | -0.2 | -0.82 | -0.66 | -0.69 | -1.51 | -0.47 | -0.7 | 1.34 | -0.29 | -0.73 | |
0.21 | 0.93 | -0.39 | -0.95 | -0.31 | -0.34 | -0.13 | -0.1 | -0.39 | 0.61 | -0.1 | -0.01 | |
0.34 | 0.79 | 0.07 | -0.56 | -0.27 | -0.35 | -0.22 | -0.09 | -0.31 | 0.27 | -0.23 | 0.02 | |
1.65 | 1.73 | -1.27 | -1.19 | -0.67 | -0.92 | -1.55 | -0.99 | -1.49 | 0.33 | -0.81 | -0.97 | |
0.13 | 0.49 | -0.14 | -0.06 | -0.1 | -0.27 | -0.26 | -0.15 | -0.25 | 0.46 | -0.04 | -0.07 | |
1.21 | 1.26 | -1.19 | -0.58 | -0.43 | -0.62 | -0.58 | -0.62 | -1.21 | 0.29 | -0.33 | 0.04 | |
0.48 | 0.29 | -0.16 | -0.2 | -0.06 | -0.02 | -0.33 | -0.24 | -0.46 | 0.38 | 0.01 | 0.01 | |
0.58 | 1.0 | -0.11 | -0.84 | -0.15 | -0.75 | -0.45 | -0.5 | -0.11 | 0.42 | -0.02 | -0.26 | |
1.49 | 2.34 | -1.42 | -3.88 | -3.95 | -2.79 | - | -1.96 | -3.29 | 1.45 | -2.05 | -2.7 | |
0.79 | 1.41 | -0.87 | -0.68 | -0.98 | -0.72 | -0.71 | -0.81 | -1.37 | 1.23 | -0.78 | -0.25 | |
0.16 | 0.55 | -0.0 | -0.51 | -0.04 | -0.34 | -0.44 | -0.01 | -0.22 | 0.42 | 0.12 | -0.08 | |
1.26 | 2.1 | -1.01 | -1.71 | -1.14 | -1.42 | -2.65 | -1.09 | -1.98 | 1.0 | -1.25 | -1.47 | |
0.12 | 0.62 | -0.03 | -0.01 | -0.29 | -0.17 | -0.57 | -0.36 | -0.4 | 0.33 | 0.25 | 0.06 | |
1.14 | 1.9 | -0.98 | -0.88 | -0.67 | -0.6 | -0.98 | -0.87 | -0.92 | -0.35 | -0.61 | -0.5 | |
1.05 | 1.15 | -1.1 | -1.18 | -0.05 | -1.0 | 0.15 | -0.24 | -0.76 | 0.39 | -0.97 | -0.05 | |
1.37 | 1.82 | -0.84 | -1.56 | -0.9 | -0.88 | -1.42 | -0.99 | -1.66 | 0.47 | -0.52 | -0.68 | |
0.13 | 0.82 | -0.46 | -0.37 | -0.24 | -0.4 | -0.25 | -0.3 | -0.69 | 0.78 | -0.06 | 0.09 | |
1.17 | 2.16 | -0.63 | -1.77 | -3.27 | -2.46 | -5.56 | -2.6 | -2.76 | 1.59 | -1.16 | -1.86 | |
0.64 | 1.03 | -0.28 | -0.45 | -0.36 | -0.49 | -0.63 | -0.21 | -0.61 | 0.76 | -0.32 | -0.54 | |
1.29 | 1.73 | -0.49 | -1.29 | -1.64 | -1.37 | -2.97 | -1.84 | -2.08 | 1.49 | -0.96 | -1.17 | |
-0.14 | 0.48 | 0.19 | -0.2 | -0.01 | -0.26 | -0.47 | -0.03 | -0.06 | 0.35 | 0.19 | -0.36 | |
0.74 | 1.37 | -1.04 | -0.65 | -0.76 | -0.65 | -0.85 | -0.87 | -1.54 | 1.2 | -0.44 | -0.14 | |
-0.16 | 0.49 | 0.02 | -0.05 | -0.26 | -0.32 | -0.3 | -0.28 | 0.01 | 0.55 | 0.03 | -0.06 | |
1.33 | 1.89 | -1.18 | -1.65 | -2.09 | -1.52 | -5.83 | -1.25 | -2.27 | 1.51 | -0.64 | -1.74 | |
-0.03 | 1.31 | -0.18 | -0.48 | -0.71 | -0.74 | -0.29 | -0.76 | -0.69 | 1.04 | -0.14 | -0.43 | |
1.74 | 2.16 | -1.27 | -2.27 | -2.22 | -2.64 | -2.84 | -2.81 | -4.24 | 1.1 | -1.53 | -1.42 | |
0.08 | 0.76 | -0.13 | -0.25 | -0.46 | -0.35 | -0.33 | -0.44 | -0.47 | 0.9 | -0.12 | -0.08 | |
0.81 | 1.2 | -0.69 | -0.58 | -0.32 | -0.81 | -0.69 | -0.6 | -0.78 | 1.07 | -0.49 | -0.68 | |
0.21 | 1.07 | -0.25 | -0.92 | 0.01 | -0.51 | -0.74 | -0.31 | -0.69 | 1.0 | -0.12 | -0.45 | |
0.58 | 0.88 | -0.15 | -0.33 | -0.22 | -0.39 | -0.54 | -0.43 | -0.32 | 0.35 | -0.06 | -0.19 | |
0.67 | 0.79 | -0.21 | -0.65 | 0.1 | -0.34 | -0.8 | -0.02 | -0.41 | 0.17 | 0.13 | -0.35 | |
0.33 | 1.0 | 0.21 | -0.42 | -0.72 | -0.52 | -0.99 | -0.61 | -0.56 | 0.98 | -0.07 | -0.37 |
Dark gray cells indicate values where the raw expression is zero (cannot be log-transformed). Blue cells indicate samples where the expression of the gene is below average and red cells indicate the gene is expressed above average in the sample. White cells are average.