lcl|LHPG02000017.1_cds_PRW33324.1_3411 (PRW33324)

Aliases : PRW33324

Description : DNA ligase 4

Gene families : OG_01_0001786 (OrthoFinder) Phylogenetic Tree(s): OG0001786_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: lcl\|LHPG02000017.1_cds_PRW33324.1_3411
Cluster	HCCA: Cluster_22

Target	Alias	Description	ECC score	Gene Family Method	Actions
OT_11G01660.1	No alias	DNA ligase, ATP-dependent, N-terminal; DNA ligase,...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003909	DNA ligase activity	None	Extended
MF	GO:0003910	DNA ligase (ATP) activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	IEA	Interproscan
BP	GO:0006310	DNA recombination	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016886	ligase activity, forming phosphoric ester bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003964	RNA-directed DNA polymerase activity	IEP	Enrichment
MF	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	IEP	Enrichment
MF	GO:0004559	alpha-mannosidase activity	IEP	Enrichment
MF	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	IEP	Enrichment
MF	GO:0004668	protein-arginine deiminase activity	IEP	Enrichment
MF	GO:0005534	galactose binding	IEP	Enrichment
BP	GO:0006576	cellular biogenic amine metabolic process	IEP	Enrichment
BP	GO:0006595	polyamine metabolic process	IEP	Enrichment
BP	GO:0006596	polyamine biosynthetic process	IEP	Enrichment
BP	GO:0006772	thiamine metabolic process	IEP	Enrichment
MF	GO:0008483	transaminase activity	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009110	vitamin biosynthetic process	IEP	Enrichment
BP	GO:0009228	thiamine biosynthetic process	IEP	Enrichment
BP	GO:0009308	amine metabolic process	IEP	Enrichment
BP	GO:0009309	amine biosynthetic process	IEP	Enrichment
BP	GO:0009445	putrescine metabolic process	IEP	Enrichment
BP	GO:0009446	putrescine biosynthetic process	IEP	Enrichment
MF	GO:0009916	alternative oxidase activity	IEP	Enrichment
MF	GO:0015923	mannosidase activity	IEP	Enrichment
MF	GO:0015924	mannosyl-oligosaccharide mannosidase activity	IEP	Enrichment
MF	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors	IEP	Enrichment
MF	GO:0016682	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor	IEP	Enrichment
MF	GO:0016769	transferase activity, transferring nitrogenous groups	IEP	Enrichment
MF	GO:0016798	hydrolase activity, acting on glycosyl bonds	IEP	Enrichment
MF	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	IEP	Enrichment
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	IEP	Enrichment
MF	GO:0019842	vitamin binding	IEP	Enrichment
BP	GO:0030099	myeloid cell differentiation	IEP	Enrichment
BP	GO:0030154	cell differentiation	IEP	Enrichment
MF	GO:0030170	pyridoxal phosphate binding	IEP	Enrichment
BP	GO:0030218	erythrocyte differentiation	IEP	Enrichment
MF	GO:0030246	carbohydrate binding	IEP	Enrichment
BP	GO:0032502	developmental process	IEP	Enrichment
MF	GO:0034061	DNA polymerase activity	IEP	Enrichment
BP	GO:0042221	response to chemical	IEP	Enrichment
BP	GO:0042364	water-soluble vitamin biosynthetic process	IEP	Enrichment
BP	GO:0042401	cellular biogenic amine biosynthetic process	IEP	Enrichment
BP	GO:0042723	thiamine-containing compound metabolic process	IEP	Enrichment
BP	GO:0042724	thiamine-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0043015	gamma-tubulin binding	IEP	Enrichment
BP	GO:0044106	cellular amine metabolic process	IEP	Enrichment
BP	GO:0044272	sulfur compound biosynthetic process	IEP	Enrichment
BP	GO:0044283	small molecule biosynthetic process	IEP	Enrichment
BP	GO:0046677	response to antibiotic	IEP	Enrichment
MF	GO:0046983	protein dimerization activity	IEP	Enrichment
MF	GO:0048029	monosaccharide binding	IEP	Enrichment
BP	GO:0048869	cellular developmental process	IEP	Enrichment
MF	GO:0051536	iron-sulfur cluster binding	IEP	Enrichment
MF	GO:0051540	metal cluster binding	IEP	Enrichment
MF	GO:0070279	vitamin B6 binding	IEP	Enrichment
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Enrichment
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Enrichment
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR012308	DNA_ligase_ATP-dep_N	495	687
IPR012309	DNA_ligase_ATP-dep_C	1019	1131
IPR012310	DNA_ligase_ATP-dep_cent	726	996

External Links

No external refs found!

lcl|LHPG02000017.1_cds_PRW33324.1_3411 (PRW33324)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation