lcl|LHPG02000007.1_cds_PRW57014.1_9222 (PRW57014)

Aliases : PRW57014

Description : DNA topoisomerase I

Gene families : OG_01_0003092 (OrthoFinder) Phylogenetic Tree(s): OG0003092_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: lcl\|LHPG02000007.1_cds_PRW57014.1_9222
Cluster	HCCA: Cluster_97

Target	Alias	Description	ECC score	Gene Family Method	Actions
PTI_25G01290.1	No alias	High mobility group box domain; Topoisomerase C-terminal...	0.02	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005694	chromosome	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000724	double-strand break repair via homologous recombination	IEP	Enrichment
BP	GO:0000725	recombinational repair	IEP	Enrichment
MF	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity	IEP	Enrichment
MF	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	IEP	Enrichment
MF	GO:0004864	protein phosphatase inhibitor activity	IEP	Enrichment
BP	GO:0006281	DNA repair	IEP	Enrichment
BP	GO:0006302	double-strand break repair	IEP	Enrichment
BP	GO:0006310	DNA recombination	IEP	Enrichment
BP	GO:0006351	transcription, DNA-templated	IEP	Enrichment
BP	GO:0006729	tetrahydrobiopterin biosynthetic process	IEP	Enrichment
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Enrichment
MF	GO:0008124	4-alpha-hydroxytetrahydrobiopterin dehydratase activity	IEP	Enrichment
BP	GO:0009435	NAD biosynthetic process	IEP	Enrichment
MF	GO:0009916	alternative oxidase activity	IEP	Enrichment
BP	GO:0010921	regulation of phosphatase activity	IEP	Enrichment
BP	GO:0016579	protein deubiquitination	IEP	Enrichment
MF	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors	IEP	Enrichment
MF	GO:0016682	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor	IEP	Enrichment
MF	GO:0016798	hydrolase activity, acting on glycosyl bonds	IEP	Enrichment
BP	GO:0018130	heterocycle biosynthetic process	IEP	Enrichment
MF	GO:0019208	phosphatase regulator activity	IEP	Enrichment
MF	GO:0019212	phosphatase inhibitor activity	IEP	Enrichment
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Enrichment
MF	GO:0019888	protein phosphatase regulator activity	IEP	Enrichment
MF	GO:0030170	pyridoxal phosphate binding	IEP	Enrichment
BP	GO:0032774	RNA biosynthetic process	IEP	Enrichment
BP	GO:0033554	cellular response to stress	IEP	Enrichment
BP	GO:0034311	diol metabolic process	IEP	Enrichment
BP	GO:0034312	diol biosynthetic process	IEP	Enrichment
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0035303	regulation of dephosphorylation	IEP	Enrichment
BP	GO:0035304	regulation of protein dephosphorylation	IEP	Enrichment
BP	GO:0042559	pteridine-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0043666	regulation of phosphoprotein phosphatase activity	IEP	Enrichment
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:0046146	tetrahydrobiopterin metabolic process	IEP	Enrichment
BP	GO:0046165	alcohol biosynthetic process	IEP	Enrichment
BP	GO:0046173	polyol biosynthetic process	IEP	Enrichment
BP	GO:0051336	regulation of hydrolase activity	IEP	Enrichment
BP	GO:0051716	cellular response to stimulus	IEP	Enrichment
MF	GO:0070279	vitamin B6 binding	IEP	Enrichment
BP	GO:0070646	protein modification by small protein removal	IEP	Enrichment
BP	GO:0097659	nucleic acid-templated transcription	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR013498	Topo_IA_Znf	739	776
IPR009071	HMG_box_dom	1175	1232
IPR009071	HMG_box_dom	1066	1123
IPR006171	TOPRIM_domain	110	222
IPR013497	Topo_IA_cen	238	700
IPR025589	Toprim_C_rpt	828	886
IPR025589	Toprim_C_rpt	887	936

External Links

No external refs found!

lcl|LHPG02000007.1_cds_PRW57014.1_9222 (PRW57014)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation