lcl|LHPG02000004.1_cds_PRW59440.1_7064 (PRW59440)

Aliases : PRW59440

Description : DNA damage checkpoint isoform C

Gene families : OG_01_0000497 (OrthoFinder) Phylogenetic Tree(s): OG0000497_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: lcl\|LHPG02000004.1_cds_PRW59440.1_7064
Cluster	HCCA: Cluster_7

Target	Alias	Description	ECC score	Gene Family Method	Actions
TP16G00970.1	No alias	Hypothetical protein	0.02	OrthoFinder
Vocar.0014s0188.1	32888600	HRDC domain; 3'-5' exonuclease domain [Interproscan].	0.02	OrthoFinder

Type	GO Term	Name	Evidence	Source
BP	GO:0000075	cell cycle checkpoint signaling	None	Extended
BP	GO:0000077	DNA damage checkpoint signaling	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004527	exonuclease activity	None	Extended
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0007165	signal transduction	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008408	3'-5' exonuclease activity	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010564	regulation of cell cycle process	None	Extended
BP	GO:0010948	negative regulation of cell cycle process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
CC	GO:0030896	checkpoint clamp complex	IEA	Interproscan
BP	GO:0031570	DNA integrity checkpoint signaling	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0035556	intracellular signal transduction	None	Extended
BP	GO:0042770	signal transduction in response to DNA damage	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0045786	negative regulation of cell cycle	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0048519	negative regulation of biological process	None	Extended
BP	GO:0048523	negative regulation of cellular process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0051726	regulation of cell cycle	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
CC	GO:0140513	nuclear protein-containing complex	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901987	regulation of cell cycle phase transition	None	Extended
BP	GO:1901988	negative regulation of cell cycle phase transition	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003885	D-arabinono-1,4-lactone oxidase activity	IEP	Enrichment
MF	GO:0004061	arylformamidase activity	IEP	Enrichment
MF	GO:0005515	protein binding	IEP	Enrichment
MF	GO:0005516	calmodulin binding	IEP	Enrichment
CC	GO:0005694	chromosome	IEP	Enrichment
CC	GO:0005887	integral component of plasma membrane	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006568	tryptophan metabolic process	IEP	Enrichment
BP	GO:0006569	tryptophan catabolic process	IEP	Enrichment
BP	GO:0006576	cellular biogenic amine metabolic process	IEP	Enrichment
BP	GO:0006586	indolalkylamine metabolic process	IEP	Enrichment
BP	GO:0009063	cellular amino acid catabolic process	IEP	Enrichment
BP	GO:0009072	aromatic amino acid family metabolic process	IEP	Enrichment
BP	GO:0009074	aromatic amino acid family catabolic process	IEP	Enrichment
BP	GO:0009306	protein secretion	IEP	Enrichment
BP	GO:0009308	amine metabolic process	IEP	Enrichment
BP	GO:0009310	amine catabolic process	IEP	Enrichment
BP	GO:0016054	organic acid catabolic process	IEP	Enrichment
MF	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	IEP	Enrichment
MF	GO:0016854	racemase and epimerase activity	IEP	Enrichment
MF	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	IEP	Enrichment
MF	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor	IEP	Enrichment
BP	GO:0019439	aromatic compound catabolic process	IEP	Enrichment
BP	GO:0019441	tryptophan catabolic process to kynurenine	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
CC	GO:0031226	intrinsic component of plasma membrane	IEP	Enrichment
BP	GO:0032940	secretion by cell	IEP	Enrichment
BP	GO:0035592	establishment of protein localization to extracellular region	IEP	Enrichment
BP	GO:0042180	cellular ketone metabolic process	IEP	Enrichment
BP	GO:0042402	cellular biogenic amine catabolic process	IEP	Enrichment
BP	GO:0042430	indole-containing compound metabolic process	IEP	Enrichment
BP	GO:0042436	indole-containing compound catabolic process	IEP	Enrichment
BP	GO:0042537	benzene-containing compound metabolic process	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0044106	cellular amine metabolic process	IEP	Enrichment
BP	GO:0044270	cellular nitrogen compound catabolic process	IEP	Enrichment
BP	GO:0044282	small molecule catabolic process	IEP	Enrichment
BP	GO:0046218	indolalkylamine catabolic process	IEP	Enrichment
BP	GO:0046395	carboxylic acid catabolic process	IEP	Enrichment
BP	GO:0046700	heterocycle catabolic process	IEP	Enrichment
BP	GO:0046903	secretion	IEP	Enrichment
BP	GO:0051276	chromosome organization	IEP	Enrichment
BP	GO:0070189	kynurenine metabolic process	IEP	Enrichment
BP	GO:0071692	protein localization to extracellular region	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
BP	GO:0140352	export from cell	IEP	Enrichment
BP	GO:1901361	organic cyclic compound catabolic process	IEP	Enrichment
BP	GO:1901565	organonitrogen compound catabolic process	IEP	Enrichment
BP	GO:1901606	alpha-amino acid catabolic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR004302	Cellulose/chitin-bd_N	337	504
IPR002562	3'-5'_exonuclease_dom	581	749
IPR002121	HRDC_dom	940	978
IPR007150	Hus1/Mec3	1	313

External Links

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lcl|LHPG02000004.1_cds_PRW59440.1_7064 (PRW59440)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation