lcl|LHPG02000004.1_cds_PRW59221.1_7052 (PRW59221)

Aliases : PRW59221

Description : DNA replication licensing factor MCM4

Gene families : OG_01_0002239 (OrthoFinder) Phylogenetic Tree(s): OG0002239_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: lcl\|LHPG02000004.1_cds_PRW59221.1_7052
Cluster	HCCA: Cluster_73

Target	Alias	Description	ECC score	Gene Family Method
Cpa\|evm.model.tig00000144.164	tig00000144_g9157.t1	Cell cycle.interphase.DNA replication.preinitiation.MCM...	0.06	OrthoFinder
Cre07.g316850	30774860, MCM4	Cell cycle.interphase.DNA replication.preinitiation.MCM...	0.11	OrthoFinder
Cz01g46020.t1	No alias	MCM, AAA-lid domain; MCM domain [Interproscan].	0.07	OrthoFinder
Cz01g46030.t1	No alias	MCM N-terminal domain; MCM OB domain; MCM domain [Interproscan].	0.04	OrthoFinder
EOD16047	No alias	MCM, AAA-lid domain; MCM domain [Interproscan].	0.04	OrthoFinder
EOD37691	No alias	MCM OB domain; MCM, AAA-lid domain; MCM domain [Interproscan].	0.03	OrthoFinder
OT_14G01130.1	No alias	MCM, AAA-lid domain; MCM domain; MCM N-terminal domain;...	0.05	OrthoFinder
Sro408_g136940.1	Contig3193.g25229	Licensing factor MCM4	0.02	OrthoFinder
Transcript_contig_53744	53744	MCM domain; MCM N-terminal domain; MCM OB domain [Interproscan].	0.09	OrthoFinder
Vocar.0003s0114.1	32889118	MCM, AAA-lid domain; MCM N-terminal domain; MCM OB...	0.06	OrthoFinder
lcl\|BLLF01000050.1_cds_GFH06666.1_1143	HaLaN_01335, GFH06666	DNA helicase	0.02	OrthoFinder
lcl\|BLLF01002444.1_cds_GFH24102.1_18579	HaLaN_21829, GFH24102	DNA helicase	0.05	OrthoFinder
lcl\|VRMN01000009.1_cds_KAA8492449.1_9142	KAA8492449	DNA replication licensing factor mcm4-B	0.06	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006270	DNA replication initiation	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000444	MIS12/MIND type complex	IEP	Enrichment
CC	GO:0000775	chromosome, centromeric region	IEP	Enrichment
CC	GO:0000776	kinetochore	IEP	Enrichment
CC	GO:0000796	condensin complex	IEP	Enrichment
CC	GO:0000818	nuclear MIS12/MIND complex	IEP	Enrichment
MF	GO:0003774	motor activity	IEP	Enrichment
MF	GO:0003777	microtubule motor activity	IEP	Enrichment
MF	GO:0003896	DNA primase activity	IEP	Enrichment
MF	GO:0003924	GTPase activity	IEP	Enrichment
MF	GO:0004190	aspartic-type endopeptidase activity	IEP	Enrichment
MF	GO:0004672	protein kinase activity	IEP	Enrichment
MF	GO:0005515	protein binding	IEP	Enrichment
CC	GO:0005634	nucleus	IEP	Enrichment
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	Enrichment
BP	GO:0006323	DNA packaging	IEP	Enrichment
BP	GO:0006334	nucleosome assembly	IEP	Enrichment
BP	GO:0006468	protein phosphorylation	IEP	Enrichment
BP	GO:0006553	lysine metabolic process	IEP	Enrichment
BP	GO:0006928	movement of cell or subcellular component	IEP	Enrichment
BP	GO:0007017	microtubule-based process	IEP	Enrichment
BP	GO:0007018	microtubule-based movement	IEP	Enrichment
BP	GO:0007059	chromosome segregation	IEP	Enrichment
BP	GO:0007076	mitotic chromosome condensation	IEP	Enrichment
MF	GO:0008017	microtubule binding	IEP	Enrichment
MF	GO:0008092	cytoskeletal protein binding	IEP	Enrichment
BP	GO:0008608	attachment of spindle microtubules to kinetochore	IEP	Enrichment
MF	GO:0008837	diaminopimelate epimerase activity	IEP	Enrichment
MF	GO:0008942	nitrite reductase [NAD(P)H] activity	IEP	Enrichment
BP	GO:0009085	lysine biosynthetic process	IEP	Enrichment
BP	GO:0009089	lysine biosynthetic process via diaminopimelate	IEP	Enrichment
BP	GO:0009262	deoxyribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009263	deoxyribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0010639	negative regulation of organelle organization	IEP	Enrichment
MF	GO:0015631	tubulin binding	IEP	Enrichment
BP	GO:0016310	phosphorylation	IEP	Enrichment
MF	GO:0016462	pyrophosphatase activity	IEP	Enrichment
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	IEP	Enrichment
MF	GO:0016787	hydrolase activity	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0016854	racemase and epimerase activity	IEP	Enrichment
MF	GO:0016855	racemase and epimerase activity, acting on amino acids and derivatives	IEP	Enrichment
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Enrichment
CC	GO:0018995	host cellular component	IEP	Enrichment
BP	GO:0022402	cell cycle process	IEP	Enrichment
BP	GO:0022414	reproductive process	IEP	Enrichment
BP	GO:0030261	chromosome condensation	IEP	Enrichment
CC	GO:0031262	Ndc80 complex	IEP	Enrichment
BP	GO:0032780	negative regulation of ATPase activity	IEP	Enrichment
CC	GO:0032991	protein-containing complex	IEP	Enrichment
BP	GO:0033043	regulation of organelle organization	IEP	Enrichment
BP	GO:0033044	regulation of chromosome organization	IEP	Enrichment
CC	GO:0033643	host cell part	IEP	Enrichment
CC	GO:0033646	host intracellular part	IEP	Enrichment
CC	GO:0033647	host intracellular organelle	IEP	Enrichment
CC	GO:0033648	host intracellular membrane-bounded organelle	IEP	Enrichment
MF	GO:0036361	racemase activity, acting on amino acids and derivatives	IEP	Enrichment
CC	GO:0042025	host cell nucleus	IEP	Enrichment
CC	GO:0042555	MCM complex	IEP	Enrichment
MF	GO:0043015	gamma-tubulin binding	IEP	Enrichment
BP	GO:0043086	negative regulation of catalytic activity	IEP	Enrichment
CC	GO:0043226	organelle	IEP	Enrichment
CC	GO:0043227	membrane-bounded organelle	IEP	Enrichment
CC	GO:0043229	intracellular organelle	IEP	Enrichment
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Enrichment
BP	GO:0043462	regulation of ATPase activity	IEP	Enrichment
BP	GO:0043648	dicarboxylic acid metabolic process	IEP	Enrichment
BP	GO:0044092	negative regulation of molecular function	IEP	Enrichment
CC	GO:0044815	DNA packaging complex	IEP	Enrichment
BP	GO:0045132	meiotic chromosome segregation	IEP	Enrichment
MF	GO:0045735	nutrient reservoir activity	IEP	Enrichment
BP	GO:0046451	diaminopimelate metabolic process	IEP	Enrichment
MF	GO:0046857	oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0047661	amino-acid racemase activity	IEP	Enrichment
BP	GO:0051095	regulation of helicase activity	IEP	Enrichment
BP	GO:0051097	negative regulation of helicase activity	IEP	Enrichment
BP	GO:0051129	negative regulation of cellular component organization	IEP	Enrichment
BP	GO:0051276	chromosome organization	IEP	Enrichment
MF	GO:0051287	NAD binding	IEP	Enrichment
BP	GO:0051315	attachment of mitotic spindle microtubules to kinetochore	IEP	Enrichment
BP	GO:0065004	protein-DNA complex assembly	IEP	Enrichment
MF	GO:0070001	aspartic-type peptidase activity	IEP	Enrichment
CC	GO:0098687	chromosomal region	IEP	Enrichment
MF	GO:0098809	nitrite reductase activity	IEP	Enrichment
BP	GO:0098813	nuclear chromosome segregation	IEP	Enrichment
CC	GO:0099080	supramolecular complex	IEP	Enrichment
BP	GO:1903046	meiotic cell cycle process	IEP	Enrichment
BP	GO:1903047	mitotic cell cycle process	IEP	Enrichment
BP	GO:1905462	regulation of DNA duplex unwinding	IEP	Enrichment
BP	GO:1905463	negative regulation of DNA duplex unwinding	IEP	Enrichment
BP	GO:1905774	regulation of DNA helicase activity	IEP	Enrichment
BP	GO:1905775	negative regulation of DNA helicase activity	IEP	Enrichment
BP	GO:2001251	negative regulation of chromosome organization	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR001208	MCM_dom	441	660
IPR027925	MCM_N	131	214
IPR041562	MCM_lid	678	761
IPR033762	MCM_OB	230	357

External Links

No external refs found!

lcl|LHPG02000004.1_cds_PRW59221.1_7052 (PRW59221)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation