lcl|VRMN01000001.1_cds_KAA8499802.1_8755 (KAA8499802)

Aliases : KAA8499802

Description : DNA topoisomerase 1 beta

Gene families : OG_01_0002413 (OrthoFinder) Phylogenetic Tree(s): OG0002413_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: lcl\|VRMN01000001.1_cds_KAA8499802.1_8755
Cluster	HCCA: Cluster_87

Target	Alias	Description	ECC score	Gene Family Method
Sro1053_g235820.1	Contig4118.g31453	DNA topoisomerase 1	0.03	OrthoFinder
Sro3393_g347530.1	Contig655.g7779	DNA topoisomerase I, mitochondrial	0.02	OrthoFinder
SymbC1.scaffold143.2	143.2	Topoisomerase I C-terminal domain; DNA topoisomerase I,...	0.02	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	None	Extended
MF	GO:0003917	DNA topoisomerase type I (single strand cut, ATP-independent) activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003682	chromatin binding	IEP	Enrichment
MF	GO:0004177	aminopeptidase activity	IEP	Enrichment
CC	GO:0005743	mitochondrial inner membrane	IEP	Enrichment
BP	GO:0006357	regulation of transcription by RNA polymerase II	IEP	Enrichment
BP	GO:0008535	respiratory chain complex IV assembly	IEP	Enrichment
CC	GO:0016592	mediator complex	IEP	Enrichment
BP	GO:0017004	cytochrome complex assembly	IEP	Enrichment
CC	GO:0019866	organelle inner membrane	IEP	Enrichment
MF	GO:0030145	manganese ion binding	IEP	Enrichment
CC	GO:0030880	RNA polymerase complex	IEP	Enrichment
CC	GO:0031966	mitochondrial membrane	IEP	Enrichment
BP	GO:0033108	mitochondrial respiratory chain complex assembly	IEP	Enrichment
BP	GO:0033617	mitochondrial cytochrome c oxidase assembly	IEP	Enrichment
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	Enrichment
MF	GO:0070403	NAD+ binding	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR008336	TopoI_DNA-bd_euk	174	390
IPR013500	TopoI_cat_euk	393	617
IPR025834	TopoI_C_dom	680	749

External Links

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lcl|VRMN01000001.1_cds_KAA8499802.1_8755 (KAA8499802)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation