OT_11G00640.1


Description : Breast cancer type 2 susceptibility protein, helical domain; BRCA2, OB1 [Interproscan].


Gene families : OG_01_0004187 (OrthoFinder) Phylogenetic Tree(s): OG0004187_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: OT_11G00640.1
Cluster HCCA: Cluster_21

Target Alias Description ECC score Gene Family Method Actions
Cre13.g566900 30784466 DNA damage response.BRCC DNA-damage response... 0.04 OrthoFinder
Cz15g07050.t1 No alias Breast cancer type 2 susceptibility protein, helical... 0.03 OrthoFinder
Sro1384_g268050.1 Contig2234.g18567 Cancer type 2 susceptibility protein 0.03 OrthoFinder
Transcript_contig_78987 78987 BRCA2, OB1 [Interproscan]. 0.01 OrthoFinder
Transcript_contig_89224 89224 Breast cancer type 2 susceptibility protein, helical... 0.01 OrthoFinder
XM_002509058.1 MICPUN_62958, 62958 Hypothetical protein (BRCA2) 0.05 OrthoFinder
XM_003061613.1 MicpuC2_62866, 62866 Breast cancer type 2 susceptibility protein, helical... 0.06 OrthoFinder

Type GO Term Name Evidence Source
BP GO:0000724 double-strand break repair via homologous recombination IEA Interproscan
Type GO Term Name Evidence Source
BP GO:0000075 cell cycle checkpoint signaling IEP Enrichment
BP GO:0000077 DNA damage checkpoint signaling IEP Enrichment
MF GO:0000166 nucleotide binding IEP Enrichment
CC GO:0000808 origin recognition complex IEP Enrichment
MF GO:0003676 nucleic acid binding IEP Enrichment
MF GO:0003677 DNA binding IEP Enrichment
MF GO:0003690 double-stranded DNA binding IEP Enrichment
MF GO:0003697 single-stranded DNA binding IEP Enrichment
MF GO:0005092 GDP-dissociation inhibitor activity IEP Enrichment
MF GO:0005488 binding IEP Enrichment
MF GO:0005515 protein binding IEP Enrichment
MF GO:0005524 ATP binding IEP Enrichment
CC GO:0005634 nucleus IEP Enrichment
BP GO:0006260 DNA replication IEP Enrichment
BP GO:0006270 DNA replication initiation IEP Enrichment
BP GO:0006298 mismatch repair IEP Enrichment
BP GO:0006996 organelle organization IEP Enrichment
BP GO:0007062 sister chromatid cohesion IEP Enrichment
BP GO:0007064 mitotic sister chromatid cohesion IEP Enrichment
BP GO:0007165 signal transduction IEP Enrichment
BP GO:0007264 small GTPase mediated signal transduction IEP Enrichment
MF GO:0008276 protein methyltransferase activity IEP Enrichment
BP GO:0009059 macromolecule biosynthetic process IEP Enrichment
BP GO:0010948 negative regulation of cell cycle process IEP Enrichment
MF GO:0016278 lysine N-methyltransferase activity IEP Enrichment
MF GO:0016279 protein-lysine N-methyltransferase activity IEP Enrichment
MF GO:0017076 purine nucleotide binding IEP Enrichment
MF GO:0018024 histone-lysine N-methyltransferase activity IEP Enrichment
MF GO:0030554 adenyl nucleotide binding IEP Enrichment
CC GO:0030896 checkpoint clamp complex IEP Enrichment
MF GO:0030983 mismatched DNA binding IEP Enrichment
BP GO:0031570 DNA integrity checkpoint signaling IEP Enrichment
MF GO:0031625 ubiquitin protein ligase binding IEP Enrichment
MF GO:0032553 ribonucleotide binding IEP Enrichment
MF GO:0032555 purine ribonucleotide binding IEP Enrichment
MF GO:0032559 adenyl ribonucleotide binding IEP Enrichment
BP GO:0034645 cellular macromolecule biosynthetic process IEP Enrichment
BP GO:0035556 intracellular signal transduction IEP Enrichment
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Enrichment
MF GO:0036094 small molecule binding IEP Enrichment
MF GO:0042054 histone methyltransferase activity IEP Enrichment
BP GO:0042770 signal transduction in response to DNA damage IEP Enrichment
MF GO:0043167 ion binding IEP Enrichment
MF GO:0043168 anion binding IEP Enrichment
CC GO:0043227 membrane-bounded organelle IEP Enrichment
CC GO:0043231 intracellular membrane-bounded organelle IEP Enrichment
MF GO:0044389 ubiquitin-like protein ligase binding IEP Enrichment
BP GO:0045786 negative regulation of cell cycle IEP Enrichment
BP GO:0051276 chromosome organization IEP Enrichment
MF GO:0097159 organic cyclic compound binding IEP Enrichment
MF GO:0097367 carbohydrate derivative binding IEP Enrichment
MF GO:1901265 nucleoside phosphate binding IEP Enrichment
MF GO:1901363 heterocyclic compound binding IEP Enrichment
BP GO:1901988 negative regulation of cell cycle phase transition IEP Enrichment
BP GO:1903047 mitotic cell cycle process IEP Enrichment
InterPro domains Description Start Stop
IPR015187 BRCA2_OB_1 649 766
IPR015252 BRCA2_hlx 570 645
No external refs found!