OT_01G05960.1

Description : Dihydrofolate reductase domain; Thymidylate synthase/dCMP hydroxymethylase domain [Interproscan].

Gene families : OG_01_0002862 (OrthoFinder) Phylogenetic Tree(s): OG0002862_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: OT_01G05960.1
Cluster	HCCA: Cluster_21

Target	Alias	Description	ECC score	Gene Family Method
Cre17.g715900	30781940	Coenzyme metabolism.tetrahydrofolate...	0.07	OrthoFinder
Dusal.0422s00002.1	33186848	Thymidylate synthase/dCMP hydroxymethylase domain [Interproscan].	0.02	OrthoFinder
EOD13547	No alias	Dihydrofolate reductase domain; Thymidylate...	0.09	OrthoFinder
Sro174_g076600.1	Contig4298.g32444	Thymidylate synthase	0.05	OrthoFinder
XM_002502500.1	MICPUN_58650, 58650	Bifunctional dihydrofolate reductase-thymidylate...	0.16	OrthoFinder
XM_003056851.1	MicpuC2_56456, 56456	Bifunctional dihydrofolate reductase-thymidylate...	0.05	OrthoFinder
lcl\|BLLF01003473.1_cds_GFH27435.1_21912	HaLaN_25755, GFH27435	Bifunctional dihydrofolate reductase-thymidylate synthase	0.02	OrthoFinder
lcl\|LHPG02000012.1_cds_PRW44987.1_1730	PRW44987	Bifunctional dihydrofolate reductase-thymidylate synthase	0.04	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004146	dihydrofolate reductase activity	IEA	Interproscan
BP	GO:0006575	cellular modified amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006760	folic acid-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009396	folic acid-containing compound biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	None	Extended
MF	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0042398	cellular modified amino acid biosynthetic process	None	Extended
BP	GO:0042558	pteridine-containing compound metabolic process	None	Extended
BP	GO:0042559	pteridine-containing compound biosynthetic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0046653	tetrahydrofolate metabolic process	None	Extended
BP	GO:0046654	tetrahydrofolate biosynthetic process	IEA	Interproscan
BP	GO:0055114	obsolete oxidation-reduction process	IEA	Interproscan
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
BP	GO:0000723	telomere maintenance	IEP	Enrichment
CC	GO:0000776	kinetochore	IEP	Enrichment
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003677	DNA binding	IEP	Enrichment
MF	GO:0003678	DNA helicase activity	IEP	Enrichment
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Enrichment
MF	GO:0004556	alpha-amylase activity	IEP	Enrichment
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEP	Enrichment
MF	GO:0004806	triglyceride lipase activity	IEP	Enrichment
MF	GO:0005319	lipid transporter activity	IEP	Enrichment
MF	GO:0005488	binding	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
CC	GO:0005634	nucleus	IEP	Enrichment
CC	GO:0005694	chromosome	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006259	DNA metabolic process	IEP	Enrichment
BP	GO:0006260	DNA replication	IEP	Enrichment
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	Enrichment
BP	GO:0006270	DNA replication initiation	IEP	Enrichment
BP	GO:0006275	regulation of DNA replication	IEP	Enrichment
BP	GO:0006869	lipid transport	IEP	Enrichment
BP	GO:0006996	organelle organization	IEP	Enrichment
BP	GO:0007062	sister chromatid cohesion	IEP	Enrichment
BP	GO:0007064	mitotic sister chromatid cohesion	IEP	Enrichment
BP	GO:0009059	macromolecule biosynthetic process	IEP	Enrichment
MF	GO:0009916	alternative oxidase activity	IEP	Enrichment
BP	GO:0010639	negative regulation of organelle organization	IEP	Enrichment
BP	GO:0016043	cellular component organization	IEP	Enrichment
MF	GO:0016298	lipase activity	IEP	Enrichment
MF	GO:0016682	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor	IEP	Enrichment
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	IEP	Enrichment
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	IEP	Enrichment
MF	GO:0016779	nucleotidyltransferase activity	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
CC	GO:0018995	host cellular component	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
CC	GO:0031262	Ndc80 complex	IEP	Enrichment
BP	GO:0032200	telomere organization	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
BP	GO:0032780	negative regulation of ATPase activity	IEP	Enrichment
CC	GO:0033643	host cell part	IEP	Enrichment
CC	GO:0033646	host intracellular part	IEP	Enrichment
CC	GO:0033647	host intracellular organelle	IEP	Enrichment
CC	GO:0033648	host intracellular membrane-bounded organelle	IEP	Enrichment
MF	GO:0034061	DNA polymerase activity	IEP	Enrichment
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
CC	GO:0042025	host cell nucleus	IEP	Enrichment
MF	GO:0042162	telomeric DNA binding	IEP	Enrichment
CC	GO:0042555	MCM complex	IEP	Enrichment
MF	GO:0043047	single-stranded telomeric DNA binding	IEP	Enrichment
BP	GO:0043086	negative regulation of catalytic activity	IEP	Enrichment
MF	GO:0043138	3'-5' DNA helicase activity	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0043170	macromolecule metabolic process	IEP	Enrichment
CC	GO:0043226	organelle	IEP	Enrichment
CC	GO:0043229	intracellular organelle	IEP	Enrichment
BP	GO:0043462	regulation of ATPase activity	IEP	Enrichment
BP	GO:0044092	negative regulation of molecular function	IEP	Enrichment
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Enrichment
BP	GO:0051095	regulation of helicase activity	IEP	Enrichment
BP	GO:0051097	negative regulation of helicase activity	IEP	Enrichment
BP	GO:0051129	negative regulation of cellular component organization	IEP	Enrichment
BP	GO:0051276	chromosome organization	IEP	Enrichment
BP	GO:0060249	anatomical structure homeostasis	IEP	Enrichment
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	IEP	Enrichment
BP	GO:0071840	cellular component organization or biogenesis	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
MF	GO:0097159	organic cyclic compound binding	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
MF	GO:0098847	sequence-specific single stranded DNA binding	IEP	Enrichment
CC	GO:0099080	supramolecular complex	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
MF	GO:1901363	heterocyclic compound binding	IEP	Enrichment
BP	GO:1905462	regulation of DNA duplex unwinding	IEP	Enrichment
BP	GO:1905463	negative regulation of DNA duplex unwinding	IEP	Enrichment
BP	GO:1905774	regulation of DNA helicase activity	IEP	Enrichment
BP	GO:1905775	negative regulation of DNA helicase activity	IEP	Enrichment
BP	GO:2001251	negative regulation of chromosome organization	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR023451	Thymidate_synth/dCMP_Mease_dom	217	499
IPR001796	DHFR_dom	7	189

External Links

No external refs found!

OT_01G05960.1

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation