EOD35437

Description : Leucyl-tRNA synthetase [Ensembl].

Gene families : OG_01_0001825 (OrthoFinder) Phylogenetic Tree(s): OG0001825_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: EOD35437
Cluster	HCCA: Cluster_292

Target	Alias	Description	ECC score	Gene Family Method
Cre13.g578451	30784550	Protein biosynthesis.aminoacyl-tRNA synthetase...	0.03	OrthoFinder
Cz08g08090.t1	No alias	Aminoacyl-tRNA synthetase, class Ia; Methionyl/Leucyl...	0.02	OrthoFinder
Dusal.0166s00010.1	33188736	Leucyl-tRNA synthetase, editing domain; Aminoacyl-tRNA...	0.02	OrthoFinder
OT_06G00490.1	No alias	Aminoacyl-tRNA synthetase, class Ia;...	0.01	OrthoFinder
PTI_16G01600.1	No alias	Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase,...	0.04	OrthoFinder
Sro497_g154690.1	Contig738.g8451	Leucine--tRNA ligase	0.02	OrthoFinder
Sro497_g154690.2	No alias	Methionyl/Leucyl tRNA synthetase; Leucyl-tRNA...	0.02	OrthoFinder
TP03G01360.1	No alias	Aminoacyl-tRNA synthetase, class Ia; Leucyl-tRNA...	0.04	OrthoFinder
Transcript_contig_55916	55916	Methionyl/Leucyl tRNA synthetase; Leucyl-tRNA...	0.01	OrthoFinder
Transcript_contig_61002	61002	Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase,...	0.02	OrthoFinder
Vocar.0001s0129.1	32885622	Aminoacyl-tRNA synthetase, class Ia; Leucyl-tRNA...	0.02	OrthoFinder
XM_003059540.1	MicpuC2_58989, 58989	Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase,...	0.02	OrthoFinder
lcl\|BLLF01001901.1_cds_GFH21760.1_16237	HaLaN_19124, GFH21760	Hypothetical protein	0.02	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan
MF	GO:0002161	aminoacyl-tRNA editing activity	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006418	tRNA aminoacylation for protein translation	IEA	Interproscan
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043038	amino acid activation	None	Extended
BP	GO:0043039	tRNA aminoacylation	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0052689	carboxylic ester hydrolase activity	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000151	ubiquitin ligase complex	IEP	Enrichment
CC	GO:0000152	nuclear ubiquitin ligase complex	IEP	Enrichment
MF	GO:0000295	adenine nucleotide transmembrane transporter activity	IEP	Enrichment
MF	GO:0003690	double-stranded DNA binding	IEP	Enrichment
MF	GO:0003855	3-dehydroquinate dehydratase activity	IEP	Enrichment
MF	GO:0003924	GTPase activity	IEP	Enrichment
MF	GO:0004358	glutamate N-acetyltransferase activity	IEP	Enrichment
MF	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity	IEP	Enrichment
MF	GO:0004470	malic enzyme activity	IEP	Enrichment
MF	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity	IEP	Enrichment
MF	GO:0004518	nuclease activity	IEP	Enrichment
MF	GO:0004525	ribonuclease III activity	IEP	Enrichment
MF	GO:0004664	prephenate dehydratase activity	IEP	Enrichment
MF	GO:0004665	prephenate dehydrogenase (NADP+) activity	IEP	Enrichment
MF	GO:0004827	proline-tRNA ligase activity	IEP	Enrichment
MF	GO:0005047	signal recognition particle binding	IEP	Enrichment
MF	GO:0005346	purine ribonucleotide transmembrane transporter activity	IEP	Enrichment
MF	GO:0005525	GTP binding	IEP	Enrichment
CC	GO:0005680	anaphase-promoting complex	IEP	Enrichment
CC	GO:0005737	cytoplasm	IEP	Enrichment
CC	GO:0005785	signal recognition particle receptor complex	IEP	Enrichment
BP	GO:0006072	glycerol-3-phosphate metabolic process	IEP	Enrichment
BP	GO:0006433	prolyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006457	protein folding	IEP	Enrichment
BP	GO:0006525	arginine metabolic process	IEP	Enrichment
BP	GO:0006526	arginine biosynthetic process	IEP	Enrichment
BP	GO:0006558	L-phenylalanine metabolic process	IEP	Enrichment
BP	GO:0006570	tyrosine metabolic process	IEP	Enrichment
BP	GO:0006571	tyrosine biosynthetic process	IEP	Enrichment
BP	GO:0006612	protein targeting to membrane	IEP	Enrichment
BP	GO:0006613	cotranslational protein targeting to membrane	IEP	Enrichment
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	IEP	Enrichment
BP	GO:0006721	terpenoid metabolic process	IEP	Enrichment
BP	GO:0006766	vitamin metabolic process	IEP	Enrichment
BP	GO:0006767	water-soluble vitamin metabolic process	IEP	Enrichment
BP	GO:0006771	riboflavin metabolic process	IEP	Enrichment
BP	GO:0007346	regulation of mitotic cell cycle	IEP	Enrichment
MF	GO:0008238	exopeptidase activity	IEP	Enrichment
MF	GO:0008514	organic anion transmembrane transporter activity	IEP	Enrichment
MF	GO:0008521	acetyl-CoA transmembrane transporter activity	IEP	Enrichment
BP	GO:0008652	cellular amino acid biosynthetic process	IEP	Enrichment
MF	GO:0008685	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity	IEP	Enrichment
MF	GO:0008686	3,4-dihydroxy-2-butanone-4-phosphate synthase activity	IEP	Enrichment
MF	GO:0008977	prephenate dehydrogenase (NAD+) activity	IEP	Enrichment
BP	GO:0009056	catabolic process	IEP	Enrichment
BP	GO:0009057	macromolecule catabolic process	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009064	glutamine family amino acid metabolic process	IEP	Enrichment
BP	GO:0009072	aromatic amino acid family metabolic process	IEP	Enrichment
BP	GO:0009073	aromatic amino acid family biosynthetic process	IEP	Enrichment
BP	GO:0009084	glutamine family amino acid biosynthetic process	IEP	Enrichment
BP	GO:0009094	L-phenylalanine biosynthetic process	IEP	Enrichment
BP	GO:0009095	aromatic amino acid family biosynthetic process, prephenate pathway	IEP	Enrichment
BP	GO:0009110	vitamin biosynthetic process	IEP	Enrichment
BP	GO:0009231	riboflavin biosynthetic process	IEP	Enrichment
CC	GO:0009507	chloroplast	IEP	Enrichment
CC	GO:0009536	plastid	IEP	Enrichment
BP	GO:0010564	regulation of cell cycle process	IEP	Enrichment
BP	GO:0010965	regulation of mitotic sister chromatid separation	IEP	Enrichment
MF	GO:0015215	nucleotide transmembrane transporter activity	IEP	Enrichment
MF	GO:0015216	purine nucleotide transmembrane transporter activity	IEP	Enrichment
MF	GO:0015605	organophosphate ester transmembrane transporter activity	IEP	Enrichment
MF	GO:0015932	nucleobase-containing compound transmembrane transporter activity	IEP	Enrichment
BP	GO:0016053	organic acid biosynthetic process	IEP	Enrichment
BP	GO:0016114	terpenoid biosynthetic process	IEP	Enrichment
MF	GO:0016462	pyrophosphatase activity	IEP	Enrichment
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Enrichment
MF	GO:0016615	malate dehydrogenase activity	IEP	Enrichment
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016791	phosphatase activity	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0016829	lyase activity	IEP	Enrichment
MF	GO:0016830	carbon-carbon lyase activity	IEP	Enrichment
MF	GO:0016832	aldehyde-lyase activity	IEP	Enrichment
MF	GO:0016835	carbon-oxygen lyase activity	IEP	Enrichment
MF	GO:0016836	hydro-lyase activity	IEP	Enrichment
MF	GO:0016849	phosphorus-oxygen lyase activity	IEP	Enrichment
MF	GO:0016854	racemase and epimerase activity	IEP	Enrichment
MF	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	IEP	Enrichment
MF	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	IEP	Enrichment
MF	GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	IEP	Enrichment
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Enrichment
MF	GO:0019001	guanyl nucleotide binding	IEP	Enrichment
BP	GO:0019725	cellular homeostasis	IEP	Enrichment
MF	GO:0019842	vitamin binding	IEP	Enrichment
BP	GO:0030071	regulation of mitotic metaphase/anaphase transition	IEP	Enrichment
BP	GO:0030163	protein catabolic process	IEP	Enrichment
MF	GO:0030170	pyridoxal phosphate binding	IEP	Enrichment
MF	GO:0030976	thiamine pyrophosphate binding	IEP	Enrichment
CC	GO:0031461	cullin-RING ubiquitin ligase complex	IEP	Enrichment
MF	GO:0032296	double-stranded RNA-specific ribonuclease activity	IEP	Enrichment
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Enrichment
BP	GO:0033043	regulation of organelle organization	IEP	Enrichment
BP	GO:0033044	regulation of chromosome organization	IEP	Enrichment
BP	GO:0033045	regulation of sister chromatid segregation	IEP	Enrichment
BP	GO:0042364	water-soluble vitamin biosynthetic process	IEP	Enrichment
MF	GO:0042578	phosphoric ester hydrolase activity	IEP	Enrichment
BP	GO:0042726	flavin-containing compound metabolic process	IEP	Enrichment
BP	GO:0042727	flavin-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0042887	amide transmembrane transporter activity	IEP	Enrichment
MF	GO:0043021	ribonucleoprotein complex binding	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044283	small molecule biosynthetic process	IEP	Enrichment
MF	GO:0044877	protein-containing complex binding	IEP	Enrichment
BP	GO:0045047	protein targeting to ER	IEP	Enrichment
BP	GO:0045454	cell redox homeostasis	IEP	Enrichment
BP	GO:0046168	glycerol-3-phosphate catabolic process	IEP	Enrichment
BP	GO:0046394	carboxylic acid biosynthetic process	IEP	Enrichment
MF	GO:0047952	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	IEP	Enrichment
BP	GO:0051128	regulation of cellular component organization	IEP	Enrichment
MF	GO:0051287	NAD binding	IEP	Enrichment
BP	GO:0051668	localization within membrane	IEP	Enrichment
BP	GO:0051726	regulation of cell cycle	IEP	Enrichment
BP	GO:0051983	regulation of chromosome segregation	IEP	Enrichment
BP	GO:0052646	alditol phosphate metabolic process	IEP	Enrichment
MF	GO:0070008	serine-type exopeptidase activity	IEP	Enrichment
MF	GO:0070279	vitamin B6 binding	IEP	Enrichment
BP	GO:0070972	protein localization to endoplasmic reticulum	IEP	Enrichment
MF	GO:0071077	adenosine 3',5'-bisphosphate transmembrane transporter activity	IEP	Enrichment
BP	GO:0072599	establishment of protein localization to endoplasmic reticulum	IEP	Enrichment
BP	GO:0072657	protein localization to membrane	IEP	Enrichment
BP	GO:0090150	establishment of protein localization to membrane	IEP	Enrichment
CC	GO:0140534	endoplasmic reticulum protein-containing complex	IEP	Enrichment
BP	GO:1901136	carbohydrate derivative catabolic process	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment
MF	GO:1901505	carbohydrate derivative transmembrane transporter activity	IEP	Enrichment
BP	GO:1901565	organonitrogen compound catabolic process	IEP	Enrichment
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:1901575	organic substance catabolic process	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment
BP	GO:1901605	alpha-amino acid metabolic process	IEP	Enrichment
BP	GO:1901607	alpha-amino acid biosynthetic process	IEP	Enrichment
MF	GO:1901682	sulfur compound transmembrane transporter activity	IEP	Enrichment
BP	GO:1901987	regulation of cell cycle phase transition	IEP	Enrichment
BP	GO:1901990	regulation of mitotic cell cycle phase transition	IEP	Enrichment
BP	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	IEP	Enrichment
BP	GO:1902221	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process	IEP	Enrichment
BP	GO:1902223	erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process	IEP	Enrichment
BP	GO:1905818	regulation of chromosome separation	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR015413	Methionyl/Leucyl_tRNA_Synth	103	234
IPR002300	aa-tRNA-synth_Ia	645	693
IPR013155	M/V/L/I-tRNA-synth_anticd-bd	749	857
IPR025709	Leu_tRNA-synth_edit	283	466

External Links

No external refs found!

EOD35437

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation