Cpa|evm.model.tig00001224.8 (tig00001224_g7630.t1)

Aliases : tig00001224_g7630.t1

Description : DNA damage response.DNA repair mechanisms.mismatch repair (MMR).MSH2-x mismatch repair heterodimers.MSH2 component

Gene families : OG_01_0000718 (OrthoFinder) Phylogenetic Tree(s): OG0000718_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Cpa\|evm.model.tig00001224.8
Cluster	HCCA: Cluster_49

Target	Alias	Description	ECC score	Gene Family Method
Cre01.g003463	30789210	DNA mismatch repair protein MSH2 OS=Zea mays	0.1	OrthoFinder
Cz05g29090.t1	No alias	DNA mismatch repair protein MutS, C-terminal; DNA...	0.06	OrthoFinder
Dusal.0326s00004.1	33186765	DNA mismatch repair protein MutS, core; DNA mismatch...	0.03	OrthoFinder
EOD15291	No alias	DNA mismatch repair protein MutS, core; DNA mismatch...	0.07	OrthoFinder
EOD21949	No alias	DNA mismatch repair protein muts [Ensembl].	0.09	OrthoFinder
OT_10G02070.1	No alias	DNA mismatch repair protein MutS, connector domain; DNA...	0.09	OrthoFinder
PTI_06G01110.1	No alias	DNA mismatch repair protein MutS, core; DNA mismatch...	0.05	OrthoFinder
Sro301_g111920.1	Contig455.g6140	Protein MutS	0.06	OrthoFinder
Sro552_g165070.1	Contig2064.g17687	Protein MutS	0.01	OrthoFinder
TP03G05730.1	No alias	DNA mismatch repair protein MutS, C-terminal [Interproscan].	0.05	OrthoFinder
Transcript_contig_54773	54773	DNA mismatch repair protein MutS, clamp; DNA mismatch...	0.01	OrthoFinder
Vocar.0013s0084.1	32896505	DNA mismatch repair protein MutS, C-terminal; DNA...	0.05	OrthoFinder
lcl\|VRMN01000013.1_cds_KAA8491466.1_6276	KAA8491466	DNA mismatch repair protein msh-2	0.04	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	Interproscan
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000151	ubiquitin ligase complex	IEP	Enrichment
CC	GO:0000152	nuclear ubiquitin ligase complex	IEP	Enrichment
MF	GO:0003896	DNA primase activity	IEP	Enrichment
MF	GO:0003909	DNA ligase activity	IEP	Enrichment
MF	GO:0003910	DNA ligase (ATP) activity	IEP	Enrichment
MF	GO:0004797	thymidine kinase activity	IEP	Enrichment
MF	GO:0005515	protein binding	IEP	Enrichment
CC	GO:0005634	nucleus	IEP	Enrichment
CC	GO:0005680	anaphase-promoting complex	IEP	Enrichment
BP	GO:0006220	pyrimidine nucleotide metabolic process	IEP	Enrichment
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0006231	dTMP biosynthetic process	IEP	Enrichment
BP	GO:0006270	DNA replication initiation	IEP	Enrichment
BP	GO:0006275	regulation of DNA replication	IEP	Enrichment
BP	GO:0007346	regulation of mitotic cell cycle	IEP	Enrichment
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009124	nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009129	pyrimidine nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009162	deoxyribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009177	pyrimidine deoxyribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009219	pyrimidine deoxyribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009262	deoxyribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009263	deoxyribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009265	2'-deoxyribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009394	2'-deoxyribonucleotide metabolic process	IEP	Enrichment
BP	GO:0010564	regulation of cell cycle process	IEP	Enrichment
BP	GO:0010639	negative regulation of organelle organization	IEP	Enrichment
BP	GO:0010824	regulation of centrosome duplication	IEP	Enrichment
BP	GO:0010826	negative regulation of centrosome duplication	IEP	Enrichment
BP	GO:0010948	negative regulation of cell cycle process	IEP	Enrichment
BP	GO:0010965	regulation of mitotic sister chromatid separation	IEP	Enrichment
MF	GO:0016779	nucleotidyltransferase activity	IEP	Enrichment
MF	GO:0016886	ligase activity, forming phosphoric ester bonds	IEP	Enrichment
MF	GO:0019136	deoxynucleoside kinase activity	IEP	Enrichment
MF	GO:0019205	nucleobase-containing compound kinase activity	IEP	Enrichment
MF	GO:0019206	nucleoside kinase activity	IEP	Enrichment
BP	GO:0019692	deoxyribose phosphate metabolic process	IEP	Enrichment
BP	GO:0030030	cell projection organization	IEP	Enrichment
BP	GO:0030031	cell projection assembly	IEP	Enrichment
BP	GO:0030071	regulation of mitotic metaphase/anaphase transition	IEP	Enrichment
CC	GO:0031461	cullin-RING ubiquitin ligase complex	IEP	Enrichment
BP	GO:0032780	negative regulation of ATPase activity	IEP	Enrichment
BP	GO:0032886	regulation of microtubule-based process	IEP	Enrichment
BP	GO:0032954	regulation of cytokinetic process	IEP	Enrichment
BP	GO:0032955	regulation of division septum assembly	IEP	Enrichment
BP	GO:0033043	regulation of organelle organization	IEP	Enrichment
BP	GO:0033044	regulation of chromosome organization	IEP	Enrichment
BP	GO:0033045	regulation of sister chromatid segregation	IEP	Enrichment
CC	GO:0036038	MKS complex	IEP	Enrichment
MF	GO:0042083	5,10-methylenetetrahydrofolate-dependent methyltransferase activity	IEP	Enrichment
CC	GO:0042555	MCM complex	IEP	Enrichment
BP	GO:0043086	negative regulation of catalytic activity	IEP	Enrichment
CC	GO:0043226	organelle	IEP	Enrichment
CC	GO:0043227	membrane-bounded organelle	IEP	Enrichment
CC	GO:0043229	intracellular organelle	IEP	Enrichment
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Enrichment
BP	GO:0043462	regulation of ATPase activity	IEP	Enrichment
BP	GO:0044087	regulation of cellular component biogenesis	IEP	Enrichment
BP	GO:0044092	negative regulation of molecular function	IEP	Enrichment
BP	GO:0044782	cilium organization	IEP	Enrichment
BP	GO:0045786	negative regulation of cell cycle	IEP	Enrichment
BP	GO:0046073	dTMP metabolic process	IEP	Enrichment
BP	GO:0046385	deoxyribose phosphate biosynthetic process	IEP	Enrichment
BP	GO:0046605	regulation of centrosome cycle	IEP	Enrichment
BP	GO:0046606	negative regulation of centrosome cycle	IEP	Enrichment
BP	GO:0048519	negative regulation of biological process	IEP	Enrichment
BP	GO:0048523	negative regulation of cellular process	IEP	Enrichment
BP	GO:0050789	regulation of biological process	IEP	Enrichment
BP	GO:0050790	regulation of catalytic activity	IEP	Enrichment
BP	GO:0050794	regulation of cellular process	IEP	Enrichment
MF	GO:0050797	thymidylate synthase (FAD) activity	IEP	Enrichment
BP	GO:0051095	regulation of helicase activity	IEP	Enrichment
BP	GO:0051097	negative regulation of helicase activity	IEP	Enrichment
BP	GO:0051128	regulation of cellular component organization	IEP	Enrichment
BP	GO:0051129	negative regulation of cellular component organization	IEP	Enrichment
BP	GO:0051493	regulation of cytoskeleton organization	IEP	Enrichment
BP	GO:0051494	negative regulation of cytoskeleton organization	IEP	Enrichment
BP	GO:0051726	regulation of cell cycle	IEP	Enrichment
BP	GO:0051983	regulation of chromosome segregation	IEP	Enrichment
BP	GO:0060271	cilium assembly	IEP	Enrichment
BP	GO:0065007	biological regulation	IEP	Enrichment
BP	GO:0065009	regulation of molecular function	IEP	Enrichment
BP	GO:0070925	organelle assembly	IEP	Enrichment
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Enrichment
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0120031	plasma membrane bounded cell projection assembly	IEP	Enrichment
BP	GO:0120036	plasma membrane bounded cell projection organization	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment
BP	GO:1901891	regulation of cell septum assembly	IEP	Enrichment
BP	GO:1901987	regulation of cell cycle phase transition	IEP	Enrichment
BP	GO:1901990	regulation of mitotic cell cycle phase transition	IEP	Enrichment
BP	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	IEP	Enrichment
BP	GO:1905462	regulation of DNA duplex unwinding	IEP	Enrichment
BP	GO:1905463	negative regulation of DNA duplex unwinding	IEP	Enrichment
BP	GO:1905774	regulation of DNA helicase activity	IEP	Enrichment
BP	GO:1905775	negative regulation of DNA helicase activity	IEP	Enrichment
BP	GO:1905818	regulation of chromosome separation	IEP	Enrichment
BP	GO:2001251	negative regulation of chromosome organization	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR007696	DNA_mismatch_repair_MutS_core	339	642
IPR000432	DNA_mismatch_repair_MutS_C	789	868
IPR000432	DNA_mismatch_repair_MutS_C	701	788
IPR007861	DNA_mismatch_repair_MutS_clamp	508	599
IPR007860	DNA_mmatch_repair_MutS_con_dom	184	322

External Links

No external refs found!

Cpa|evm.model.tig00001224.8 (tig00001224_g7630.t1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation