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| Gene | OTH95 | RCC4221 | RCC745,25uM Cu,1h | RCC745,25uM Cu,4h | RCC745,25uM Cu,12h | RCC745,250uM Cu,1h | RCC745,250uM Cu,4h | RCC745,250uM Cu,12h | RCC745,Control,0h | RCC745,Control,1h | RCC745,Control,4h | RCC745,Control,12h |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 35.68 | 50.1 | 74.44 | 65.81 | 59.9 | 58.04 | 63.3 | 60.94 | 66.73 | 68.81 | 63.35 | 61.6 | |
| 35.54 | 37.66 | 60.93 | 55.68 | 49.0 | 47.12 | 52.87 | 49.97 | 56.32 | 58.83 | 55.12 | 51.94 | |
| 21.02 | 25.95 | 17.0 | 13.01 | 12.39 | 13.93 | 9.31 | 13.89 | 12.42 | 21.4 | 11.06 | 13.4 | |
| 24.88 | 27.66 | 38.62 | 40.32 | 40.78 | 30.95 | 46.33 | 35.58 | 43.4 | 36.49 | 38.9 | 41.12 | |
| 21.49 | 22.25 | 38.54 | 46.41 | 39.16 | 37.37 | 51.15 | 39.68 | 46.15 | 30.3 | 37.23 | 45.63 | |
| 125.56 | 131.39 | 211.75 | 218.97 | 189.04 | 193.04 | 212.56 | 181.47 | 227.38 | 180.02 | 187.21 | 197.59 | |
| 33.57 | 41.65 | 18.23 | 12.76 | 15.71 | 14.97 | 6.67 | 16.85 | 12.16 | 28.05 | 17.4 | 15.16 | |
| 456.34 | 608.68 | 346.7 | 328.65 | 315.67 | 419.18 | 377.71 | 301.48 | 329.01 | 527.06 | 375.29 | 331.88 | |
| 101.39 | 166.52 | 74.19 | 63.96 | 70.56 | 58.5 | 55.03 | 69.98 | 65.33 | 113.69 | 74.6 | 67.38 | |
| 109.0 | 119.41 | 89.56 | 76.08 | 69.74 | 94.74 | 76.46 | 86.82 | 80.9 | 108.13 | 86.53 | 87.06 | |
| 370.72 | 404.09 | 729.71 | 701.77 | 646.82 | 552.64 | 673.08 | 636.48 | 710.2 | 635.85 | 698.38 | 657.43 | |
| 130.45 | 114.57 | 167.83 | 200.75 | 163.82 | 163.5 | 196.4 | 179.45 | 183.43 | 148.17 | 165.09 | 181.8 | |
| 284.84 | 211.95 | 319.11 | 375.73 | 340.44 | 338.72 | 446.82 | 353.26 | 341.81 | 253.94 | 341.39 | 464.74 | |
| 103.66 | 128.09 | 110.72 | 138.7 | 170.98 | 123.56 | 189.57 | 140.59 | 154.44 | 98.87 | 143.41 | 160.62 | |
| 417.48 | 405.9 | 457.49 | 573.9 | 707.52 | 473.54 | 910.3 | 683.71 | 629.21 | 406.34 | 567.47 | 696.37 | |
| 606.49 | 457.97 | 519.04 | 675.01 | 614.27 | 570.45 | 810.27 | 638.65 | 623.11 | 465.87 | 538.76 | 632.56 | |
| 114.4 | 148.76 | 146.43 | 163.45 | 203.87 | 152.48 | 251.42 | 169.44 | 182.29 | 158.17 | 169.37 | 203.11 | |
| 164.81 | 176.37 | 208.54 | 280.67 | 224.64 | 196.43 | 321.89 | 226.74 | 265.79 | 166.67 | 220.6 | 288.25 | |
| 771.03 | 662.91 | 781.06 | 1030.69 | 1030.28 | 835.75 | 1276.75 | 966.51 | 1041.25 | 798.61 | 935.9 | 1004.27 | |
| 1368.63 | 1093.49 | 1135.22 | 1744.65 | 1624.72 | 1299.39 | 2188.75 | 1546.5 | 1652.96 | 1015.42 | 1434.51 | 1658.17 | |
| 1565.31 | 1285.41 | 1110.34 | 1601.33 | 1868.59 | 1540.62 | 2539.48 | 1648.72 | 1768.65 | 800.5 | 1607.43 | 1792.55 | |
| 117.97 | 145.93 | 180.56 | 258.51 | 220.28 | 197.24 | 293.48 | 235.79 | 208.38 | 140.0 | 198.05 | 239.8 | |
| 443.51 | 380.24 | 551.52 | 678.06 | 663.23 | 547.98 | 911.82 | 699.42 | 641.8 | 418.35 | 602.03 | 683.83 | |
| 317.01 | 323.12 | 432.73 | 515.24 | 463.0 | 359.43 | 587.48 | 441.47 | 482.8 | 404.19 | 433.32 | 490.35 | |
| 332.79 | 370.57 | 433.62 | 570.3 | 522.27 | 440.37 | 672.54 | 489.21 | 525.63 | 384.0 | 489.92 | 578.83 | |
| 271.43 | 224.73 | 290.65 | 381.64 | 318.95 | 294.85 | 434.45 | 321.68 | 334.56 | 223.43 | 320.07 | 342.16 | |
| 973.02 | 1055.16 | 1813.59 | 2294.77 | 1971.89 | 1861.72 | 2648.17 | 1945.69 | 2231.64 | 1397.85 | 1866.17 | 2076.6 | |
| 16.31 | 15.89 | 28.63 | 21.67 | 29.6 | 21.57 | 24.54 | 28.96 | 23.71 | 19.29 | 24.99 | 22.77 | |
| 246.72 | 258.4 | 141.46 | 70.83 | 98.0 | 100.54 | 38.18 | 126.56 | 72.03 | 186.77 | 110.18 | 77.99 | |
| 45.96 | 51.02 | 17.9 | 10.41 | 11.7 | 12.55 | 4.21 | 12.25 | 8.01 | 29.54 | 16.61 | 11.62 | |
| 27.63 | 56.52 | 79.98 | 70.81 | 62.66 | 54.64 | 77.94 | 68.81 | 73.71 | 69.44 | 74.09 | 66.2 | |
| 98.68 | 88.67 | 89.49 | 118.4 | 139.27 | 109.05 | 152.01 | 115.21 | 119.03 | 79.72 | 107.46 | 121.79 | |
| 1259.4 | 898.06 | 1054.01 | 1084.28 | 1478.09 | 1203.11 | 1493.44 | 1355.02 | 1230.24 | 953.28 | 1366.0 | 1179.89 | |
| 52.4 | 76.18 | 131.07 | 151.11 | 104.22 | 97.37 | 137.07 | 101.95 | 133.38 | 105.95 | 103.87 | 129.91 | |
| 8.18 | 7.55 | 9.88 | 10.41 | 10.92 | 7.42 | 15.22 | 12.03 | 10.73 | 8.53 | 10.84 | 12.04 | |
| 134.55 | 147.69 | 168.88 | 192.17 | 207.78 | 166.29 | 220.47 | 197.71 | 191.39 | 148.18 | 183.5 | 179.38 | |
| 13.64 | 16.42 | 13.42 | 15.47 | 15.63 | 10.76 | 13.45 | 12.93 | 15.75 | 14.15 | 14.34 | 15.59 | |
| 1176.38 | 1889.23 | 967.32 | 1037.41 | 846.47 | 681.39 | 1059.53 | 943.5 | 957.62 | 1007.24 | 826.7 | 988.02 | |
| 54.01 | 48.61 | 52.56 | 39.83 | 42.63 | 40.57 | 40.18 | 48.33 | 40.26 | 45.2 | 49.0 | 41.47 | |
| 2.86 | 2.26 | 1.99 | 1.15 | 1.39 | 2.19 | 0.5 | 1.51 | 1.15 | 1.95 | 2.24 | 1.77 | |
| 33.68 | 35.24 | 29.41 | 25.22 | 34.9 | 26.8 | 33.29 | 34.14 | 25.9 | 28.49 | 34.91 | 33.79 | |
| 235.37 | 369.06 | 391.81 | 430.46 | 512.09 | 398.86 | 396.88 | 410.28 | 465.32 | 308.81 | 436.67 | 389.76 | |
| 20.14 | 32.62 | 12.24 | 10.98 | 8.42 | 10.66 | 6.44 | 12.16 | 8.76 | 24.14 | 13.56 | 8.84 | |
| 387.81 | 567.23 | 142.36 | 152.52 | 172.55 | 137.98 | 127.41 | 151.27 | 146.57 | 337.03 | 147.84 | 148.92 | |
| 49.71 | 46.15 | 13.94 | 1.01 | 1.01 | 5.09 | 0.0 | 1.7 | 0.0 | 25.62 | 7.29 | 8.27 | |
| 56.91 | 59.49 | 37.97 | 44.57 | 44.78 | 37.39 | 52.36 | 57.55 | 39.33 | 53.26 | 47.61 | 59.76 | |
| 46.15 | 58.5 | 37.99 | 24.87 | 33.41 | 28.34 | 29.38 | 34.07 | 29.87 | 42.21 | 35.22 | 36.28 | |
| 378.89 | 365.3 | 428.52 | 513.01 | 588.8 | 467.79 | 612.22 | 490.49 | 584.72 | 417.37 | 527.13 | 516.28 | |
| 34.14 | 25.27 | 22.61 | 17.82 | 31.38 | 23.11 | 27.57 | 30.52 | 24.88 | 22.54 | 26.07 | 23.97 | |
| 48.04 | 49.39 | 25.26 | 25.43 | 29.75 | 22.46 | 24.56 | 28.34 | 24.65 | 39.58 | 29.52 | 27.65 | |
| 115.6 | 114.93 | 145.88 | 157.94 | 145.16 | 125.04 | 154.19 | 159.41 | 158.1 | 105.07 | 143.8 | 147.54 | |
| 225.13 | 230.84 | 207.49 | 204.37 | 161.08 | 171.69 | 217.47 | 198.38 | 180.28 | 207.13 | 168.26 | 209.52 | |
| 38.29 | 366.13 | 25.47 | 20.57 | 31.99 | 19.93 | 16.89 | 31.19 | 24.22 | 18.7 | 26.21 | 15.62 | |
| 78.54 | 98.85 | 200.76 | 220.59 | 181.52 | 176.72 | 214.61 | 210.15 | 204.55 | 176.7 | 200.72 | 185.29 | |
| 15.85 | 21.01 | 18.34 | 22.01 | 18.35 | 19.42 | 18.58 | 14.45 | 21.55 | 20.88 | 19.05 | 22.52 | |
| 31.74 | 34.72 | 39.57 | 33.35 | 46.63 | 36.22 | 36.15 | 43.42 | 39.63 | 35.45 | 40.3 | 38.03 | |
| 95.93 | 138.42 | 151.95 | 164.29 | 147.1 | 147.01 | 168.63 | 168.74 | 152.15 | 166.85 | 150.09 | 164.49 | |
| 9.25 | 12.05 | 9.11 | 7.35 | 10.28 | 7.59 | 9.12 | 10.69 | 9.94 | 8.41 | 9.51 | 11.8 | |
| 124.73 | 181.41 | 52.88 | 63.01 | 52.54 | 59.81 | 59.12 | 60.6 | 54.95 | 109.53 | 47.27 | 60.6 | |
| 41.33 | 30.58 | 30.68 | 27.85 | 36.21 | 30.04 | 27.66 | 29.39 | 28.97 | 25.87 | 38.42 | 32.95 | |
| 42.43 | 37.75 | 33.79 | 29.44 | 34.43 | 33.84 | 37.77 | 33.68 | 37.14 | 46.46 | 35.66 | 36.67 | |
| 41.38 | 41.88 | 64.58 | 69.94 | 62.12 | 54.31 | 62.13 | 53.5 | 70.89 | 54.25 | 59.79 | 62.65 | |
| 220.57 | 232.04 | 268.19 | 340.79 | 386.18 | 265.68 | 461.69 | 344.16 | 350.3 | 243.78 | 346.24 | 381.09 | |
| 51.68 | 47.43 | 57.32 | 55.43 | 59.8 | 50.9 | 65.93 | 59.15 | 60.97 | 48.52 | 63.37 | 54.67 | |
| 11.71 | 13.57 | 9.28 | 6.44 | 8.19 | 6.58 | 6.14 | 7.71 | 7.25 | 11.07 | 7.94 | 7.37 | |
| 24.57 | 33.25 | 39.98 | 39.56 | 39.43 | 38.89 | 40.71 | 43.99 | 45.84 | 38.35 | 39.88 | 40.63 | |
| 28.2 | 25.6 | 40.07 | 31.14 | 37.13 | 27.06 | 40.78 | 40.78 | 36.45 | 34.22 | 42.82 | 31.05 | |
| 7.45 | 14.28 | 6.26 | 4.78 | 5.59 | 4.22 | 3.12 | 5.94 | 4.36 | 10.24 | 5.75 | 5.15 | |
| 11.82 | 20.93 | 9.09 | 5.49 | 7.84 | 6.42 | 5.59 | 8.33 | 7.24 | 12.51 | 9.2 | 6.53 | |
| 37.06 | 41.25 | 45.3 | 46.67 | 48.27 | 36.69 | 48.33 | 45.73 | 50.75 | 42.24 | 44.47 | 42.36 | |
| 32.47 | 44.06 | 22.95 | 22.71 | 28.92 | 28.65 | 28.59 | 27.46 | 23.16 | 32.53 | 29.8 | 26.87 | |
| 7.08 | 12.12 | 1.94 | 2.22 | 2.94 | 2.66 | 2.98 | 1.6 | 2.02 | 3.06 | 2.94 | 3.73 | |
| 102.54 | 194.34 | 104.73 | 123.74 | 114.65 | 96.99 | 120.58 | 106.15 | 113.05 | 120.39 | 98.85 | 120.65 | |
| 16.11 | 16.81 | 16.16 | 20.62 | 21.02 | 18.72 | 25.49 | 22.45 | 19.14 | 17.4 | 20.19 | 23.98 | |
| 763.01 | 953.15 | 937.93 | 1110.98 | 1041.56 | 1286.65 | 1234.46 | 916.95 | 1037.12 | 1420.92 | 1096.45 | 1149.07 | |
| 30.48 | 30.6 | 36.0 | 37.24 | 36.81 | 36.12 | 40.05 | 35.51 | 40.13 | 34.29 | 36.95 | 36.68 | |
| 54.32 | 81.56 | 60.92 | 50.11 | 44.18 | 47.1 | 40.37 | 64.53 | 47.82 | 90.83 | 56.11 | 45.72 | |
| 189.44 | 156.35 | 266.66 | 233.22 | 280.69 | 258.37 | 261.94 | 259.02 | 268.91 | 253.71 | 281.79 | 237.56 | |
| 67.82 | 124.91 | 61.55 | 64.69 | 62.97 | 73.62 | 73.02 | 54.64 | 67.08 | 101.54 | 74.9 | 72.22 | |
| 208.61 | 286.05 | 5.55 | 2.19 | 1.94 | 0.55 | 0.0 | 1.65 | 1.02 | 73.78 | 3.8 | 2.25 | |
| 13.52 | 19.52 | 28.54 | 31.89 | 27.48 | 21.23 | 32.67 | 23.41 | 34.42 | 28.11 | 29.42 | 32.12 | |
| 19.15 | 27.07 | 9.4 | 6.72 | 6.95 | 5.95 | 4.34 | 4.39 | 4.17 | 9.05 | 7.06 | 2.76 | |
| 47.4 | 45.21 | 58.29 | 53.26 | 57.93 | 47.16 | 48.38 | 53.97 | 54.7 | 61.86 | 60.35 | 51.05 | |
| 2253.88 | 3753.54 | 2256.4 | 1772.96 | 2206.42 | 2001.77 | 1811.35 | 2296.58 | 2049.52 | 2890.47 | 2370.72 | 1856.54 | |
| 31.27 | 23.73 | 22.01 | 18.96 | 17.55 | 14.44 | 24.5 | 25.15 | 13.18 | 28.97 | 22.57 | 19.47 | |
| 109.78 | 161.62 | 216.78 | 216.38 | 160.11 | 172.05 | 217.13 | 172.19 | 199.76 | 216.2 | 161.36 | 171.35 | |
| 600.57 | 440.22 | 638.0 | 803.36 | 950.49 | 735.57 | 1087.99 | 793.15 | 857.94 | 560.59 | 792.0 | 793.02 | |
| 11.92 | 20.7 | 13.44 | 14.22 | 15.4 | 11.9 | 12.99 | 15.43 | 16.87 | 13.35 | 15.31 | 12.98 | |
| 37.32 | 38.83 | 22.78 | 21.72 | 24.73 | 20.06 | 24.21 | 25.15 | 20.41 | 30.94 | 25.12 | 21.77 | |
| 382.82 | 586.71 | 208.08 | 174.18 | 262.51 | 319.17 | 151.71 | 122.41 | 152.43 | 347.41 | 271.52 | 247.15 | |
| 70.88 | 56.92 | 69.0 | 51.51 | 66.88 | 53.6 | 50.35 | 59.4 | 56.87 | 67.76 | 66.06 | 50.34 | |
| 1857.03 | 2791.78 | 4619.72 | 4238.59 | 5160.51 | 5963.24 | 5746.07 | 4848.73 | 4501.02 | 4696.6 | 4461.25 | 4753.64 | |
| 13.29 | 12.42 | 13.7 | 9.96 | 13.5 | 9.14 | 8.91 | 12.91 | 11.86 | 13.25 | 12.77 | 9.19 | |
| 83.81 | 111.64 | 167.65 | 172.49 | 123.87 | 124.0 | 148.94 | 142.08 | 148.82 | 134.9 | 129.19 | 141.34 | |
| 102.38 | 131.05 | 135.15 | 133.83 | 137.77 | 103.71 | 122.91 | 135.75 | 142.07 | 134.75 | 135.49 | 128.32 | |
| 35.51 | 35.65 | 45.54 | 49.76 | 42.75 | 42.22 | 65.47 | 43.94 | 52.21 | 45.1 | 46.41 | 57.37 | |
| 47.68 | 59.95 | 66.18 | 71.34 | 66.56 | 51.21 | 66.86 | 69.6 | 67.85 | 60.39 | 60.74 | 64.54 | |
| 662.05 | 640.28 | 766.31 | 955.63 | 969.26 | 1008.55 | 1230.41 | 910.83 | 883.1 | 1020.74 | 940.68 | 1089.47 | |
| 297.51 | 585.98 | 107.84 | 71.93 | 72.13 | 80.41 | 52.09 | 76.42 | 72.67 | 355.98 | 99.4 | 75.87 | |
| 25.44 | 25.42 | 16.55 | 10.35 | 13.31 | 9.75 | 11.45 | 13.66 | 11.33 | 17.83 | 14.58 | 13.16 | |
| 260.83 | 320.31 | 131.98 | 142.44 | 195.34 | 173.5 | 141.62 | 173.62 | 128.98 | 130.63 | 167.1 | 160.64 | |
| 352.01 | 425.41 | 574.77 | 585.06 | 734.94 | 536.42 | 669.16 | 737.28 | 608.07 | 494.93 | 679.08 | 593.23 | |
| 10.98 | 12.96 | 21.36 | 16.61 | 13.59 | 13.75 | 13.91 | 17.62 | 18.3 | 20.39 | 15.18 | 14.61 | |
| 85.92 | 81.48 | 214.79 | 248.35 | 177.36 | 156.18 | 216.02 | 181.66 | 224.48 | 177.45 | 175.58 | 218.71 | |
| 35.36 | 31.13 | 48.81 | 42.39 | 57.4 | 48.15 | 47.53 | 55.91 | 51.57 | 48.16 | 51.77 | 50.42 | |
| 293.4 | 271.64 | 226.91 | 186.39 | 244.55 | 244.29 | 189.88 | 235.64 | 190.47 | 238.72 | 281.26 | 203.87 | |
| 55.67 | 52.54 | 64.22 | 45.49 | 55.57 | 44.27 | 58.85 | 55.12 | 55.86 | 61.86 | 61.95 | 55.45 |
Raw expression values (TPM normalized), Green cells indicate low expression and red high. (Dark gray cells indicate missing values)