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Heatmap: Cluster_38 (HCCA)

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Gene
OTH95
RCC4221
RCC745,25uM Cu,1h
RCC745,25uM Cu,4h
RCC745,25uM Cu,12h
RCC745,250uM Cu,1h
RCC745,250uM Cu,4h
RCC745,250uM Cu,12h
RCC745,Control,0h
RCC745,Control,1h
RCC745,Control,4h
RCC745,Control,12h
19.34 22.87 12.88 7.07 10.42 6.74 7.28 6.55 9.2 15.83 10.57 7.55
15.43 17.32 4.83 4.49 5.34 5.26 3.71 4.33 3.74 9.98 5.33 4.94
17.34 14.69 7.29 6.81 7.27 6.25 4.16 7.8 4.07 8.35 5.83 6.37
42.43 51.29 17.14 15.86 22.49 19.12 11.02 18.55 17.3 19.89 23.64 12.71
509.72 475.23 326.35 284.85 423.55 392.87 195.68 357.73 280.34 444.42 412.6 266.89
173.37 146.95 67.78 59.04 84.96 75.5 41.96 62.34 59.49 132.17 83.05 62.26
39.26 35.16 20.75 20.04 23.24 18.41 17.22 19.02 22.08 26.58 24.17 19.43
92.88 167.77 65.63 49.56 58.42 59.57 31.12 54.83 47.91 88.43 67.82 49.49
19.6 30.61 5.18 2.95 5.21 4.98 1.52 4.37 3.25 13.78 5.64 3.0
0.0 0.26 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
0.11 0.11 0.0 0.45 0.31 0.0 0.18 0.0 0.0 0.22 0.15 0.0
97.57 89.19 50.86 45.29 67.45 50.82 45.81 59.18 50.08 65.75 58.46 51.61
16.66 16.05 3.84 2.71 2.44 2.16 1.29 3.83 2.56 8.16 3.4 3.25
76.33 81.91 46.48 44.36 60.55 53.93 40.14 55.88 44.92 54.13 55.22 34.24
289.94 215.52 176.28 181.09 260.39 225.9 179.19 213.93 195.56 234.12 233.66 167.81
18.92 20.43 3.58 2.83 2.97 3.09 0.54 1.87 2.59 7.02 4.08 2.26
291.56 334.7 214.24 250.59 279.82 240.06 248.48 275.14 247.72 265.85 272.68 258.41
166.4 309.32 51.98 105.59 164.7 97.78 54.62 79.11 86.03 186.94 147.25 68.62
97.96 96.32 53.41 37.1 70.44 49.58 30.87 56.64 45.15 61.23 63.11 44.99
99.65 89.37 53.62 33.98 37.92 37.36 22.37 40.95 38.03 71.27 49.0 38.4
1.41 4.28 3.06 2.33 0.3 0.98 0.52 0.37 1.97 5.72 1.43 0.84
36.68 41.99 40.0 35.93 36.45 32.24 27.54 32.2 39.21 51.78 37.94 35.69
30.47 33.54 17.25 18.66 22.02 19.05 19.63 16.59 23.97 24.46 21.4 22.31
62.75 51.48 24.55 12.35 16.46 15.58 3.49 19.88 11.07 32.88 21.44 12.96
12.9 8.45 1.87 1.53 0.85 1.37 0.74 0.53 0.79 6.13 0.67 0.1
11.91 62.47 11.45 5.87 9.27 4.87 0.0 0.0 2.43 8.81 0.0 0.0
82.77 96.68 36.63 42.13 46.72 39.62 26.42 42.9 33.68 85.82 45.98 31.13
135.56 152.41 41.81 32.05 31.77 35.1 21.79 24.14 39.38 93.09 31.56 42.13
0.03 0.07 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.57
34.25 31.09 8.45 7.03 4.93 3.9 2.58 3.05 6.76 20.26 5.26 5.44
555.41 582.64 255.32 273.65 306.28 292.0 182.24 271.03 285.62 565.48 380.12 223.63
162.19 171.65 139.62 148.58 147.87 129.85 120.68 124.85 151.95 180.82 151.36 134.64
2058.59 4747.86 86.28 39.47 53.05 71.82 0.0 13.34 65.01 1105.14 47.51 56.71
584.44 579.82 12.57 12.55 8.2 8.46 5.49 0.0 12.65 124.39 17.58 4.3
37.68 44.52 33.33 32.32 39.04 30.61 33.2 38.21 31.24 33.73 33.48 37.43
46.3 63.72 30.36 26.59 38.21 30.65 23.98 30.79 29.31 32.14 37.2 28.67
96.39 85.72 46.1 31.48 34.12 57.5 0.0 13.83 25.39 92.3 27.88 33.04
22.15 16.93 9.22 8.83 6.75 6.57 6.3 8.97 9.01 11.19 7.04 9.58
150.01 184.48 120.64 111.88 171.26 144.45 106.45 134.0 133.16 137.99 157.99 129.23
29.65 58.56 9.93 6.26 11.79 9.15 4.24 10.6 5.07 16.47 9.85 9.06
672.59 740.84 181.8 118.18 80.68 114.56 14.98 91.26 81.63 377.29 156.61 126.39
14.34 19.03 1.91 1.25 0.99 1.35 0.39 0.75 0.59 12.17 1.61 1.64
11.42 13.63 5.81 4.45 6.56 4.21 4.28 5.05 4.11 9.53 6.77 4.55
21.66 21.66 12.47 7.3 6.43 8.05 4.38 6.42 7.14 17.85 8.45 7.06
33.89 44.91 16.02 17.96 24.43 21.61 16.71 20.49 19.39 34.33 23.57 22.41
52.44 57.33 31.63 24.56 30.3 29.52 23.64 34.92 30.85 40.62 31.25 30.65
7.18 5.35 2.02 1.51 1.37 1.63 0.7 1.26 1.44 3.77 1.74 3.01
3.62 131.93 4.8 1.4 4.25 7.81 0.74 0.0 5.0 72.59 1.28 0.64
99.23 132.59 100.65 99.79 99.43 101.04 89.1 92.79 94.45 123.59 104.37 90.68
46.18 42.24 19.74 16.34 15.68 12.98 9.73 15.56 11.21 34.26 21.05 18.03
56.03 57.19 24.81 20.94 27.79 24.73 19.71 26.03 18.98 42.47 30.32 21.62
74.78 106.52 42.42 30.93 46.15 41.43 33.01 43.77 36.25 69.07 46.35 38.68
413.37 326.65 128.42 115.59 138.61 117.3 101.48 139.4 128.72 179.48 130.93 111.61
46.79 53.16 33.25 29.94 43.15 30.47 29.3 33.37 30.55 56.58 41.83 31.81
90.69 81.89 50.24 36.99 51.03 43.76 31.74 46.75 41.76 67.09 56.43 40.52
339.07 358.85 260.92 235.3 283.35 264.27 209.51 248.46 252.77 409.43 287.98 238.61
22.41 27.55 16.54 11.51 14.17 15.2 6.95 13.75 11.33 20.32 14.84 10.49
21.38 20.99 11.88 6.67 7.49 5.68 4.42 7.46 6.07 17.23 9.41 9.58
12.49 13.6 4.48 2.4 1.15 2.86 0.84 2.31 1.58 7.21 3.67 2.42
44.97 59.09 31.63 32.47 39.33 34.09 34.83 31.9 34.57 52.71 38.26 36.39
132.42 132.09 29.07 9.37 15.84 10.36 9.16 11.82 14.98 45.19 23.18 8.79
48.77 92.29 28.44 16.71 30.13 24.69 12.68 26.77 21.88 32.91 29.46 23.22
36.15 35.5 9.66 5.93 9.28 9.28 2.97 8.73 7.33 14.7 9.78 5.84
145.54 149.89 32.44 23.18 23.9 31.72 11.47 27.99 24.45 66.08 33.34 26.31
34.01 37.41 12.51 5.78 6.54 9.96 2.28 8.0 10.0 14.5 16.33 4.32
30.59 32.76 31.09 23.32 37.98 26.62 22.31 31.27 28.35 33.22 32.83 25.37
19.6 19.88 10.46 5.38 6.86 6.87 3.61 5.23 7.79 12.86 6.75 3.1
76.57 61.61 11.4 5.51 5.97 8.78 0.91 3.3 5.03 13.02 9.09 4.65
221.77 222.04 124.09 126.38 190.51 150.53 116.98 161.83 135.19 143.16 155.48 118.6
73.17 77.71 30.29 23.96 35.6 28.32 18.43 31.33 25.39 49.5 31.9 23.96
15.15 14.98 2.41 1.02 1.99 2.2 0.48 1.77 1.23 3.78 2.15 1.7
247.21 215.25 135.69 144.12 169.37 151.61 120.14 167.77 139.35 200.05 172.19 127.15
273.2 249.09 126.51 144.18 181.59 163.3 149.94 185.58 143.1 193.78 166.44 147.9
53.7 70.57 21.8 23.73 44.1 28.51 24.87 30.74 32.67 38.95 37.56 23.23
99.21 164.1 81.16 90.05 149.09 107.06 87.38 117.36 98.71 138.23 130.02 80.98
90.0 135.25 85.43 74.67 98.45 80.75 81.97 89.83 90.96 117.34 88.25 75.75
20.55 12.18 9.4 7.12 5.61 5.48 1.26 6.14 8.32 10.79 10.17 4.98
0.0 0.61 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.58
66.73 64.25 25.52 12.47 13.79 16.25 3.59 12.15 12.48 35.68 20.02 14.77
22.69 21.01 6.12 4.54 5.53 5.66 2.11 5.73 5.26 8.58 6.36 5.27
9.85 13.33 7.97 1.14 4.87 3.01 2.17 4.36 2.21 7.26 6.43 4.03
3.27 1.58 0.97 0.64 0.79 0.41 0.29 0.85 0.73 0.71 0.92 0.79
1.11 2.4 8.83 0.0 0.0 0.0 4.68 0.0 4.26 6.11 0.0 0.0
0.05 0.03 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
14.6 11.92 1.11 1.06 0.91 1.16 0.22 0.49 0.76 6.85 1.17 1.22
2.19 3.02 0.42 0.0 0.15 0.18 0.18 0.42 0.0 0.62 0.69 0.31
204.32 197.91 106.15 134.95 188.86 148.64 144.5 174.06 140.04 147.46 155.01 141.67
76.3 81.89 43.0 48.62 63.49 53.46 42.28 57.17 45.58 59.87 57.95 54.73
33.94 27.99 6.05 3.35 0.69 3.87 0.9 2.66 2.61 14.27 2.95 3.64
7.41 9.3 1.46 1.29 2.65 1.27 0.16 1.37 1.08 4.03 3.27 1.31
410.84 523.89 221.48 191.04 305.46 251.63 163.45 277.51 199.65 343.69 261.98 201.5
544.43 744.23 83.74 103.23 63.74 84.96 38.69 47.11 48.18 149.3 85.83 45.02
89.87 98.31 40.58 29.27 38.86 31.58 26.81 27.97 30.18 55.15 39.08 26.75
3.95 4.54 3.93 4.42 2.41 2.08 5.81 4.55 4.37 4.71 5.49 3.56
123.63 176.94 38.98 22.78 31.25 36.14 15.41 30.16 29.69 75.53 39.31 26.59
5.55 29.36 3.76 1.96 2.4 5.66 3.58 0.95 4.45 14.69 4.54 9.74
0.7 1.65 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
251.96 235.02 80.12 61.88 87.71 80.52 45.08 78.56 69.13 137.45 95.04 82.09
67.94 70.1 32.4 18.06 18.09 18.49 11.89 20.98 22.49 48.8 35.76 18.49
39.43 37.11 21.22 17.19 20.3 17.88 11.02 19.75 15.63 24.3 24.83 16.24
150.9 170.43 118.49 128.5 165.57 134.61 137.43 150.38 140.57 149.25 157.73 128.68
34.87 36.81 17.96 14.0 19.96 17.41 10.88 25.76 19.25 19.74 20.05 11.88
50.63 59.47 20.8 12.76 23.55 23.96 8.54 17.57 13.88 36.25 26.13 16.78
32.04 30.96 16.49 10.72 11.86 13.1 5.02 12.13 9.55 21.39 16.0 14.66
83.57 78.3 52.66 55.07 69.41 74.58 43.32 67.08 51.06 73.42 75.82 55.69
26.88 23.25 9.28 9.86 11.96 8.4 7.31 9.48 8.07 14.0 9.83 7.79
11.95 10.77 1.66 0.33 0.72 0.94 0.49 1.99 0.16 4.85 1.6 1.24
25.4 26.88 8.27 3.7 3.73 3.2 3.49 4.96 3.35 15.34 4.83 2.57
16.98 18.53 1.46 0.75 0.33 0.92 0.21 0.3 0.19 3.53 0.35 0.61
199.67 193.28 114.49 126.04 130.91 122.49 111.98 114.91 122.46 160.07 137.32 115.32
13.2 11.68 5.58 3.35 4.89 3.06 2.4 5.32 3.58 7.24 5.78 2.82
13.89 15.63 0.5 0.31 0.21 0.42 0.11 0.35 0.42 2.13 0.32 0.61
536.24 506.92 294.5 254.24 311.05 279.87 235.56 315.74 258.57 367.5 299.04 286.77
337.84 333.05 171.31 187.2 273.0 244.38 158.81 217.57 192.5 318.04 242.04 175.35
66.56 87.69 40.63 39.49 60.97 44.11 40.72 52.07 43.14 48.49 51.48 41.76
205.61 230.94 102.43 53.63 47.4 61.87 12.85 61.82 46.28 154.96 68.52 46.82
193.13 303.93 35.42 21.82 28.86 28.02 22.47 46.02 30.72 25.35 34.96 36.48
37.98 53.41 20.84 12.02 12.25 14.64 6.85 11.7 13.45 26.96 16.91 12.55
22.59 25.94 6.62 2.83 3.53 3.58 1.48 3.79 3.0 15.25 5.42 2.4
9.8 14.03 11.79 10.47 14.59 9.77 9.75 12.62 11.74 13.09 14.75 11.29
119.06 114.69 48.17 21.51 29.87 27.86 7.97 29.68 32.67 75.53 38.63 21.73
25.22 21.54 6.63 3.38 4.19 2.81 1.45 2.9 2.17 12.9 7.09 3.72
49.62 49.93 35.04 25.65 33.04 29.66 19.33 29.16 28.68 52.02 31.36 26.85
10.53 12.49 3.16 1.16 1.26 1.36 0.21 1.11 0.63 6.07 2.12 0.92
85.49 97.89 66.43 39.63 37.73 40.45 25.55 38.22 36.33 60.38 49.33 44.0
0.05 0.05 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
248.4 343.49 168.21 152.95 192.46 163.67 140.09 160.46 164.56 293.27 185.35 144.92
621.66 986.32 516.77 437.38 593.69 560.71 289.48 486.19 511.75 866.71 636.7 432.92
17.71 16.37 4.64 2.81 2.0 2.83 1.73 2.13 3.19 7.96 3.28 1.28
36.6 45.09 22.66 18.34 25.54 22.0 20.22 20.06 20.89 34.24 24.83 20.32
0.0 0.34 0.0 2.21 0.9 4.65 3.07 0.0 5.11 0.75 0.0 9.99
296.64 428.0 152.53 136.21 185.91 168.28 87.11 153.28 146.61 349.26 183.28 136.14
9.8 11.71 6.33 3.32 3.27 3.61 1.95 4.21 3.57 6.87 4.65 2.4
11.39 14.08 9.06 6.3 8.99 6.86 5.91 6.57 7.72 9.98 8.66 6.96
50.23 47.22 6.46 4.11 3.95 3.62 1.67 4.31 2.49 11.19 4.34 4.45
30.77 32.5 5.74 5.82 3.4 2.81 2.34 2.68 1.9 17.0 8.38 6.16
64.84 70.84 29.16 21.39 22.86 26.36 11.53 26.92 18.27 35.31 25.67 21.26
169.66 194.83 107.86 99.1 125.73 103.13 81.59 104.07 99.9 162.31 128.56 104.57
19.69 22.52 5.84 5.08 6.17 5.77 3.88 4.88 5.33 13.72 6.84 5.21
10.67 12.93 0.17 0.18 0.71 0.55 0.22 0.72 0.18 0.09 0.73 0.63
38.63 46.24 26.1 16.75 16.04 19.61 9.22 18.17 16.33 33.27 21.36 13.47
6.95 6.14 0.34 0.21 0.2 0.21 0.11 0.0 0.21 2.43 0.23 0.11
34.04 34.88 9.51 4.51 2.88 3.87 0.84 2.35 2.11 10.24 6.37 4.57
16.31 16.8 6.66 4.3 3.39 3.43 2.57 3.88 3.21 9.59 4.34 4.41
66.43 86.08 23.91 10.11 7.53 9.8 3.3 4.91 9.15 36.98 11.69 9.99
9.82 10.96 3.46 2.03 4.72 4.87 1.57 4.89 2.41 5.5 5.18 3.91
28.15 31.47 13.09 8.84 13.82 10.2 5.42 11.84 8.39 24.05 12.97 10.55
17.72 15.97 7.44 5.15 2.69 4.58 1.25 3.04 3.86 11.07 5.14 4.91
51.15 58.37 31.82 21.73 21.42 24.9 13.71 19.05 21.64 38.67 23.3 19.29
11.94 18.05 3.01 2.61 2.67 3.6 1.61 1.99 1.99 10.39 2.78 2.06
17.93 20.88 5.45 5.03 6.34 5.4 4.94 5.78 6.87 7.28 8.57 6.99
18.57 12.19 3.22 2.58 1.75 1.42 1.33 1.31 1.59 10.9 2.59 1.77
38.77 95.53 81.52 61.09 51.84 69.52 40.94 51.68 61.95 66.06 70.92 51.71
589.5 442.29 5.78 3.41 3.28 4.36 1.23 5.18 4.64 12.13 8.05 4.08
301.1 338.87 54.04 36.83 55.63 44.77 19.67 41.91 36.03 153.0 57.35 38.75
48.05 71.72 4.82 3.11 4.05 2.58 1.57 3.3 2.87 24.06 5.71 2.28
56.15 139.69 77.83 71.64 62.12 72.28 56.58 62.35 74.05 129.24 78.28 65.88
979.97 1599.12 620.32 467.6 538.28 608.94 340.9 501.94 508.38 706.56 605.55 534.82
12.61 17.84 4.66 3.2 2.99 2.2 2.32 4.3 2.05 8.31 6.14 2.93
99.05 88.48 47.35 30.18 28.85 39.26 21.17 41.29 39.92 58.5 40.92 26.54
32.18 22.82 11.36 10.98 5.67 7.92 4.3 7.76 7.96 13.81 11.4 8.43
208.7 219.69 18.15 11.53 26.11 19.11 5.17 15.77 10.52 64.8 18.36 14.15
313.35 298.03 122.01 101.43 135.82 130.24 82.6 129.51 107.02 173.08 122.17 107.81
196.02 166.31 55.57 36.26 35.49 40.59 27.48 40.19 38.28 36.28 44.19 36.24
836.8 846.79 324.37 299.08 427.05 399.47 308.43 382.09 313.05 656.96 417.02 347.62
179.81 194.59 85.62 75.08 125.85 112.4 68.57 118.66 93.63 148.0 120.62 79.33
56.11 53.39 26.29 11.49 26.29 21.03 14.82 25.25 20.01 32.03 23.61 17.03
48.52 40.68 24.09 15.33 14.67 14.49 7.02 15.69 15.06 33.83 17.73 12.05
25.22 27.38 6.79 5.69 5.25 4.65 2.39 3.8 4.46 18.76 7.07 5.49
162.32 130.19 99.17 91.66 103.03 83.76 78.5 97.47 91.5 116.95 95.28 83.39
75.45 63.36 34.45 15.79 25.26 22.05 17.35 30.42 20.21 32.73 32.42 24.13
23.76 34.08 17.57 10.59 11.0 9.63 5.86 6.37 11.07 27.72 9.49 7.36
185.32 248.6 186.28 205.16 242.42 225.67 165.29 222.91 204.45 259.09 233.6 185.45
166.47 178.65 54.7 51.44 76.7 68.35 42.36 61.39 58.97 133.03 71.14 54.32
53.05 66.98 31.49 31.48 41.92 33.55 38.78 30.25 38.78 29.68 38.05 33.65
18.77 22.85 8.24 2.37 2.34 6.17 0.99 4.14 6.08 8.41 4.45 4.79
98.4 98.06 55.98 35.71 48.92 45.57 22.83 45.66 38.83 83.4 59.8 31.95
29.78 29.3 14.71 10.33 9.49 11.03 6.64 11.33 10.56 22.77 13.49 11.48
19.38 21.64 1.31 2.37 1.11 0.58 0.0 0.3 0.58 6.17 1.74 1.47
5.89 6.7 0.98 0.89 0.0 0.61 0.15 0.0 0.86 3.96 0.44 0.29
568.4 593.22 347.94 274.18 366.76 349.91 208.68 353.94 270.46 442.9 351.4 301.43
11.96 9.85 6.55 3.47 1.98 2.45 1.18 3.4 2.95 4.17 3.91 3.71
104.32 96.7 79.32 75.87 119.5 90.2 84.62 107.92 82.6 86.83 92.92 73.83
192.95 172.06 39.62 27.29 27.29 34.04 13.82 28.29 28.54 88.86 35.49 31.49
7.95 7.94 4.18 2.97 2.65 2.48 1.9 3.02 2.81 6.71 2.98 3.4
20.0 22.9 7.1 3.35 3.87 3.9 2.48 4.36 5.02 11.6 5.51 4.2
0.11 0.91 0.42 0.5 0.59 0.24 0.0 0.0 0.61 0.86 0.0 0.5
0.47 2.83 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.13 0.0 3.97
98.52 88.44 73.61 70.51 96.89 75.21 99.63 96.11 87.25 84.32 76.88 85.55
321.01 452.95 170.45 195.77 285.05 238.11 163.79 219.52 193.49 376.5 252.3 210.76
53.94 72.97 24.46 18.69 20.44 27.61 14.1 20.09 20.17 48.65 25.57 20.07
0.01 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
8.11 8.27 1.91 1.22 0.62 0.82 0.34 1.46 0.5 1.71 0.55 0.71
917.37 1094.84 363.29 211.37 226.02 260.36 79.38 229.7 193.67 518.21 289.73 235.62
332.9 350.96 128.5 113.82 139.49 133.92 77.56 126.26 117.18 225.49 138.85 105.11
531.03 485.79 302.72 362.95 421.8 388.32 356.13 385.9 350.68 371.56 383.33 353.66
282.09 290.52 178.26 206.75 228.66 215.87 166.27 214.08 193.82 247.56 240.88 193.74
31.29 31.06 18.22 15.4 15.87 16.3 11.03 13.5 14.29 17.64 14.47 17.09
27.19 30.08 9.76 10.4 14.12 13.1 7.99 12.56 11.61 20.56 13.23 10.43
109.1 110.3 22.51 12.19 14.03 10.63 0.43 9.45 10.58 24.5 18.15 13.11
9.73 9.71 2.55 2.0 2.58 2.46 0.83 2.41 1.54 2.67 2.56 1.64
102.92 109.02 38.82 29.34 26.31 27.68 26.98 28.08 34.22 46.55 29.57 27.81
212.85 204.79 181.65 206.19 235.01 204.59 163.18 204.92 205.46 213.42 216.12 175.23
35.25 37.42 17.37 12.41 17.81 13.4 9.41 18.48 14.54 27.23 19.44 13.93
19.96 18.66 5.31 4.89 5.99 4.41 4.68 5.81 5.15 7.74 5.5 3.63
23.04 33.18 8.86 6.81 8.63 7.99 3.2 7.64 5.03 12.01 9.31 6.04
780.04 4379.24 2792.0 2224.2 2042.89 2536.5 2029.78 2325.19 2386.64 4198.08 2183.18 2076.26

Details

Raw expression values (TPM normalized), Green cells indicate low expression and red high. (Dark gray cells indicate missing values)