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Heatmap: Cluster_23 (HCCA)

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Gene
OTH95
RCC4221
RCC745,25uM Cu,1h
RCC745,25uM Cu,4h
RCC745,25uM Cu,12h
RCC745,250uM Cu,1h
RCC745,250uM Cu,4h
RCC745,250uM Cu,12h
RCC745,Control,0h
RCC745,Control,1h
RCC745,Control,4h
RCC745,Control,12h
46.83 42.25 42.63 38.17 43.54 32.62 38.8 44.81 37.22 29.31 43.95 42.57
20.3 14.95 11.04 11.68 9.42 9.12 9.36 11.83 10.71 8.1 9.63 8.88
19.52 15.69 17.93 17.38 18.01 17.22 16.87 17.17 20.09 19.58 19.28 16.12
11.3 7.36 6.21 7.97 6.03 6.73 7.17 7.63 6.41 4.42 6.78 8.89
56.93 26.52 27.61 23.06 30.39 26.69 25.38 31.75 26.1 32.83 31.35 26.59
20.79 11.54 11.35 9.46 9.83 8.69 9.39 10.36 8.68 8.66 10.19 11.74
26.11 22.43 14.66 12.27 17.08 12.86 9.05 13.68 8.95 15.69 17.8 12.85
50.4 28.12 23.68 20.8 42.48 32.71 27.26 37.94 28.24 22.8 31.58 30.94
29.25 21.26 19.9 17.85 15.82 15.17 14.37 13.8 14.71 24.86 17.97 18.51
49.15 37.54 58.1 49.19 55.77 50.64 47.73 55.01 58.37 52.88 60.17 48.25
30.92 19.2 15.31 12.92 13.94 12.72 12.05 19.44 13.94 19.09 14.8 18.71
16.14 10.15 6.18 8.26 8.33 8.18 7.65 9.05 7.23 7.03 8.05 6.3
4.93 4.93 4.25 2.73 2.96 3.71 2.59 2.03 3.71 4.47 2.62 2.49
57.17 22.24 28.42 12.21 16.79 18.27 10.8 36.57 33.81 23.79 7.99 11.87
21.7 18.12 27.39 27.96 23.28 21.65 28.24 23.84 23.49 26.89 23.15 22.73
45.45 22.41 8.46 4.14 5.83 2.69 2.94 3.23 4.78 13.29 4.37 4.62
25.86 13.51 7.67 6.26 8.69 5.39 10.31 6.41 8.21 10.72 7.01 8.79
914.06 562.47 677.21 800.34 787.08 687.66 1045.23 883.87 711.38 532.22 692.94 746.65
405.05 253.36 221.12 312.72 352.39 316.66 475.7 328.54 311.71 222.51 336.7 331.85
66.68 42.18 49.43 45.83 56.66 40.26 52.72 54.81 50.36 55.02 55.88 50.15
23.98 16.28 15.0 10.56 15.4 10.78 12.79 9.6 15.0 11.16 11.44 11.3
39.64 29.48 38.17 33.83 30.85 28.25 32.38 30.54 34.55 32.39 31.65 29.87
73.04 75.87 113.31 75.02 85.26 80.5 73.74 92.42 91.23 107.56 103.71 69.5
17.86 9.89 8.99 5.95 10.7 6.74 7.58 8.6 7.22 7.23 9.51 9.42
59.97 44.1 28.89 23.46 32.71 29.41 32.15 35.36 27.44 41.65 31.71 30.62
30.38 21.86 26.24 19.14 22.12 18.95 19.48 21.68 20.59 25.81 21.91 16.19
52.12 31.08 27.26 33.75 37.75 29.63 37.3 34.81 31.12 34.67 34.37 36.46
87.04 51.62 59.22 60.96 56.68 54.04 56.58 63.12 65.71 45.93 57.66 61.69
124.91 59.75 55.01 27.02 28.01 29.25 18.34 31.94 37.6 54.85 36.31 34.58
75.56 51.78 67.17 62.51 51.46 49.36 64.77 62.55 58.51 54.61 57.57 59.27
98.37 53.7 69.49 50.0 78.14 54.77 63.64 78.91 64.98 38.5 75.3 56.28
38.51 23.19 36.98 33.37 35.36 28.9 34.01 30.91 32.95 28.7 37.62 36.07
26.95 14.16 18.74 17.21 21.58 17.95 18.89 27.74 19.26 13.64 17.92 22.87
296.32 180.91 171.85 192.21 187.39 166.04 207.36 186.88 171.52 165.25 168.03 203.46
43.25 32.71 30.33 36.85 36.86 28.05 41.11 35.59 34.15 34.74 33.73 38.11
16.22 11.29 12.26 8.92 11.53 9.87 8.19 11.27 10.88 9.75 9.8 9.05
19.21 11.7 13.83 14.36 14.3 13.38 17.7 14.79 12.68 10.81 15.06 17.17
33.09 16.12 19.91 23.53 27.95 20.48 25.06 25.37 26.23 13.83 25.01 20.11
17.83 16.87 23.12 23.82 23.0 17.26 23.54 25.0 22.84 17.84 21.77 19.11
36.95 28.37 22.95 14.79 17.53 15.31 15.12 22.4 19.99 23.95 21.82 17.9
15.27 12.77 12.94 10.18 11.52 9.41 9.77 11.14 12.75 14.73 12.21 11.38
840.6 546.89 265.54 411.72 401.96 289.26 346.03 418.09 338.78 220.16 368.54 343.71
45.23 38.66 35.7 44.1 50.2 39.48 51.93 43.58 44.74 36.1 41.12 44.0
135.78 91.24 92.84 73.41 111.45 98.66 108.17 110.03 96.32 83.26 104.33 92.88
77.32 45.57 43.26 39.4 60.58 45.45 50.27 53.84 44.55 54.6 52.47 46.85
237.73 169.27 136.92 126.59 162.84 126.01 133.75 168.62 126.6 124.59 162.14 130.15
12.56 11.54 9.25 9.8 15.56 10.33 14.83 12.28 10.69 11.03 12.66 10.38
106.67 92.67 130.13 77.04 104.53 100.68 81.91 105.41 101.44 109.52 126.68 90.47
103.04 71.98 98.26 92.84 92.65 91.13 92.99 84.08 100.34 92.37 96.46 86.44
44.83 26.35 11.94 10.5 15.91 11.44 14.54 12.87 11.41 12.75 13.48 13.58
129.62 100.05 115.41 96.07 87.1 105.75 77.39 98.94 93.99 134.83 112.7 91.73
190.28 92.83 110.78 126.8 158.97 162.42 163.03 131.38 131.4 107.96 148.26 137.03
72.97 55.39 61.62 56.1 70.19 57.85 63.39 65.3 68.1 52.98 63.68 59.93
109.96 81.08 95.51 75.74 74.61 74.77 61.16 75.26 75.92 105.4 87.17 64.49
64.44 28.75 29.43 40.14 46.87 36.87 47.7 43.55 35.8 26.13 38.46 46.25
128.83 101.29 89.02 88.01 100.65 86.02 82.49 87.21 101.02 91.77 101.78 88.19
64.78 34.69 17.71 9.1 13.58 10.76 8.34 13.13 8.58 23.75 17.34 10.95
52.25 35.41 36.17 31.06 35.98 30.58 25.67 32.89 32.17 30.89 40.23 28.63
31.08 18.05 29.2 21.55 22.82 23.69 16.86 25.44 25.77 28.03 26.76 23.58
27.33 18.59 22.88 18.37 18.22 18.05 13.61 18.33 19.59 21.52 21.92 16.42
133.35 113.67 125.38 154.94 130.63 117.95 149.75 131.69 135.98 123.79 117.15 138.65
24.12 14.0 22.89 18.67 19.6 19.26 20.65 20.03 21.35 14.39 23.4 18.81
17.66 15.14 17.06 14.06 15.44 10.83 17.37 17.5 17.61 16.34 16.55 13.38
41.32 36.51 47.14 38.6 40.19 35.33 41.7 40.79 42.73 38.97 38.56 41.84
45.7 33.78 29.08 29.91 23.89 24.43 20.45 20.36 27.37 25.78 27.64 22.84
46.57 36.43 42.49 47.1 53.06 41.79 49.65 55.39 50.74 44.05 48.33 40.94
26.5 21.04 27.44 25.64 27.25 21.23 33.37 25.34 30.15 24.5 24.42 26.08
39.81 29.49 35.42 34.78 51.39 37.48 45.55 47.17 39.16 33.73 45.89 38.72
19.85 10.01 12.16 7.8 8.91 6.6 7.24 9.31 9.54 10.33 10.19 8.86
114.62 74.46 68.87 58.46 59.63 59.25 53.35 64.53 66.46 54.76 67.67 54.87
13.48 11.68 11.14 8.55 13.02 7.95 13.83 15.42 8.13 10.08 10.5 11.48
70.12 37.0 47.37 37.14 40.72 33.77 41.39 42.92 39.57 44.43 45.6 44.35
144.09 123.46 102.63 110.21 80.69 71.15 89.67 90.31 102.63 128.61 94.51 83.38
80.89 76.22 73.79 58.95 69.5 60.89 55.34 73.01 64.92 67.18 74.99 61.69
19.43 11.07 19.63 20.63 14.41 14.2 17.94 18.29 18.67 17.98 20.19 15.86
15.06 9.96 14.69 10.88 7.83 6.15 9.68 5.09 9.34 9.15 10.33 7.0
31.43 31.97 29.12 19.07 24.25 19.56 18.22 27.14 22.03 29.32 24.88 22.18
24.69 18.58 21.09 16.68 20.22 17.3 18.13 19.57 15.93 17.54 19.29 18.46
18.19 15.97 12.3 9.57 10.56 11.18 9.0 10.79 10.58 15.78 13.51 10.67
499.63 204.69 309.09 205.7 303.96 249.07 340.52 299.89 216.71 235.25 286.55 300.88
53.9 38.81 46.03 48.24 45.13 43.56 41.97 42.27 46.2 49.24 47.41 44.83
61.77 44.86 24.28 20.11 16.19 13.5 10.14 18.31 18.06 25.25 21.4 14.44
271.98 199.1 105.95 93.38 58.21 68.73 17.54 111.87 78.93 144.01 93.0 51.84
69.25 22.54 120.37 105.27 93.89 95.23 111.51 92.65 109.6 85.6 104.05 105.9
20.15 5.21 11.38 4.61 5.19 4.18 3.01 5.69 6.13 5.75 8.61 4.47
25.31 23.58 21.32 17.95 18.25 14.73 15.57 18.51 16.59 19.05 22.13 14.02
103.19 73.73 79.48 67.5 57.97 56.64 60.5 62.5 66.91 69.21 62.25 63.13
351.78 230.15 282.12 255.26 342.9 299.41 368.75 372.73 297.23 284.9 333.59 285.59
45.78 32.21 40.05 36.35 46.7 36.44 45.07 43.16 40.78 33.76 42.52 38.3
39.32 32.39 26.4 30.12 37.88 30.02 33.27 26.06 32.89 31.98 36.94 31.15
132.57 88.24 73.65 70.62 68.49 73.81 61.62 65.88 64.57 94.53 72.05 77.16
26.84 28.91 13.47 9.28 11.47 8.89 8.77 11.2 9.44 26.26 12.56 9.62
26.0 19.23 19.81 11.98 15.46 15.75 13.17 14.27 17.28 17.65 15.53 12.61
6.42 3.09 7.73 7.9 7.65 4.29 10.12 7.88 7.91 4.3 6.75 9.43
57.85 33.21 53.74 49.83 59.63 45.41 62.45 52.07 57.5 38.37 60.61 52.67
58.7 27.11 45.8 44.1 54.7 47.88 40.64 48.78 43.47 38.55 53.31 42.36
266.44 249.6 259.48 225.59 201.58 214.83 226.86 192.78 221.25 331.62 243.43 257.59
107.12 58.57 72.38 63.78 66.72 58.67 55.16 84.53 57.63 54.87 79.17 53.58
50.72 45.04 35.99 41.53 35.12 36.92 33.92 40.98 45.06 30.52 35.94 37.63
81.48 96.6 67.24 62.72 83.04 66.75 66.89 71.78 66.96 76.5 77.17 64.13
72.27 34.83 54.36 52.73 39.59 35.02 53.27 45.4 49.19 46.2 45.89 49.15
65.7 50.69 58.7 52.77 54.78 45.43 52.23 56.17 50.44 56.43 48.46 56.87
101.98 76.85 130.41 104.0 102.7 100.57 98.1 109.56 110.35 125.0 119.09 98.22
10.22 5.78 2.08 0.68 1.4 1.14 0.31 1.19 1.3 2.48 0.68 1.57
23.32 18.77 10.88 11.5 12.4 11.08 10.32 12.44 10.37 15.23 13.49 10.49
182.72 173.65 148.73 143.28 133.28 130.01 133.19 139.94 146.34 147.74 147.47 127.33
30.29 21.41 17.78 16.39 13.61 17.27 12.9 11.63 13.16 21.26 17.22 16.56
14.37 8.74 5.45 3.74 2.41 4.37 2.09 4.16 2.62 7.76 5.06 3.77
118.73 102.2 77.44 74.16 85.3 71.01 78.05 89.07 79.01 70.29 77.38 75.96
34.16 15.79 13.5 11.73 16.47 14.27 15.66 16.3 17.22 8.4 14.76 14.06
64.51 49.81 33.61 32.91 42.75 32.7 29.56 34.45 31.88 39.71 37.21 32.93
4.51 2.26 1.46 2.43 1.98 2.06 1.41 4.19 3.0 1.72 1.9 2.1
82.46 50.51 70.55 75.72 72.08 66.74 86.13 67.25 71.82 54.32 72.98 74.62
14.37 11.33 5.56 4.51 7.54 4.39 4.03 7.67 3.27 4.06 6.26 3.57
21.27 18.29 30.62 18.14 14.36 15.23 12.39 12.63 23.08 25.91 17.76 15.2
12.83 5.22 3.8 2.26 2.58 2.25 3.38 2.19 2.86 5.24 3.12 2.95
37.8 33.03 34.18 34.68 37.07 31.58 36.45 32.26 37.51 40.7 36.8 33.57
29.26 13.24 11.87 7.66 5.44 6.23 4.36 4.82 8.55 16.47 5.89 5.92
16.7 14.88 12.15 14.04 12.49 14.03 11.86 13.61 12.2 16.17 15.48 14.54
8.8 4.19 1.81 0.85 2.0 0.75 0.94 1.66 0.99 1.49 1.39 1.31
28.76 19.83 25.0 26.44 26.99 21.53 27.65 27.41 24.22 21.83 25.82 26.4
31.07 18.22 12.47 8.84 9.48 10.7 9.44 10.94 10.62 11.62 11.17 10.76
18.16 14.39 11.54 10.94 10.15 11.45 6.73 11.29 10.45 14.91 11.63 10.47
51.75 35.53 32.74 28.73 20.8 24.52 24.5 25.8 27.12 32.05 28.31 26.6
46.84 31.04 40.52 33.25 36.06 34.94 32.59 43.47 36.14 28.37 38.58 29.83
16.15 9.04 11.85 9.9 10.65 9.93 12.29 11.05 10.62 9.05 11.45 12.17
46.72 36.49 35.06 35.35 32.48 29.59 33.86 31.03 36.04 43.59 38.22 31.16
117.04 113.6 112.61 96.31 103.29 91.56 94.74 102.4 104.37 112.7 110.51 93.01
9.75 5.97 4.05 4.92 6.45 4.8 5.06 4.51 4.64 4.26 5.84 4.85
37.51 20.04 27.69 22.48 25.28 23.22 28.61 27.52 26.2 21.88 29.07 24.98
79.2 60.15 64.88 67.87 68.97 65.22 67.91 69.4 69.21 68.0 69.35 68.04
123.6 91.92 101.96 90.18 98.28 92.6 92.15 90.66 94.57 111.51 103.29 87.54
20.07 17.96 16.71 14.16 16.47 15.38 14.94 14.86 14.28 16.8 17.79 11.07
17.42 10.8 10.95 10.05 11.16 11.27 8.54 10.81 8.59 8.32 11.77 10.08
20.92 11.66 9.72 7.74 7.22 7.71 9.78 9.51 5.97 9.33 8.54 9.99
32.99 22.6 20.19 21.08 28.65 19.93 28.08 27.42 24.45 17.52 26.38 24.01
60.98 59.36 40.06 27.35 26.86 29.88 22.09 29.26 31.1 43.39 33.11 33.23
72.33 42.63 58.25 74.35 72.2 61.6 88.06 90.57 76.01 48.94 64.31 66.64
2.15 0.82 0.39 0.35 0.43 0.26 0.75 0.69 0.51 0.69 0.6 0.45
41.59 23.73 40.24 32.92 26.28 27.87 34.54 30.59 36.01 25.82 33.17 30.8
24.62 20.17 28.23 27.88 35.36 29.46 26.92 33.67 33.29 26.04 34.36 24.85
13.2 10.64 11.54 8.84 10.13 8.78 8.13 10.76 8.66 12.06 10.49 9.14
64.28 51.13 67.79 60.79 46.55 41.01 49.01 55.39 60.35 60.51 54.38 54.2
13.31 10.13 9.28 7.52 7.64 7.15 9.0 8.33 7.78 7.72 8.58 7.73
23.2 13.65 15.64 15.74 14.45 12.92 13.67 13.91 15.25 16.62 15.3 14.21
177.69 159.74 131.52 81.31 70.88 89.49 51.38 80.88 82.87 169.74 99.37 81.17
36.33 29.3 35.38 25.98 31.2 27.93 28.42 32.76 30.07 37.25 32.63 28.3
49.03 42.41 49.93 44.24 41.13 39.42 40.41 52.66 44.79 42.69 44.13 41.0
34.04 21.29 24.19 16.95 22.02 16.35 20.86 22.92 22.4 23.5 23.32 17.3
122.82 47.39 50.71 47.9 53.32 44.84 49.82 54.6 52.5 54.4 53.84 47.33
90.26 72.1 31.18 32.52 22.79 26.47 23.54 26.6 27.24 39.68 24.49 24.65
21.48 12.88 17.95 12.64 15.0 13.33 14.95 14.54 18.73 18.44 15.5 13.06
23.24 15.58 14.99 11.04 15.4 14.93 15.86 15.47 14.09 16.67 15.86 14.32
44.28 30.9 12.99 13.17 20.5 20.69 13.39 15.62 14.63 21.84 16.2 13.4
18.35 8.72 12.64 7.77 10.07 9.96 9.11 10.36 13.64 7.23 11.52 9.2
23.77 11.79 18.56 16.54 21.24 17.77 23.25 17.67 17.57 14.61 17.59 19.18
41.97 35.42 34.23 35.78 30.52 23.12 36.7 34.13 35.02 38.2 32.13 31.17
16.78 10.18 13.64 13.97 15.8 12.18 16.96 13.65 15.24 12.17 15.38 14.9
371.06 163.16 130.15 147.11 185.46 181.34 205.45 183.69 148.71 172.28 195.84 192.72
22.24 11.31 19.16 8.67 9.27 7.15 0.0 5.72 12.67 15.11 9.92 9.58
40.44 23.24 24.75 28.32 27.31 25.34 31.05 20.75 31.8 21.03 24.02 29.22
14.65 7.36 4.43 3.12 1.67 3.16 1.48 2.97 2.96 3.81 3.95 2.57
124.03 103.52 73.97 77.0 95.73 87.76 66.73 79.34 87.06 82.29 81.36 87.89
67.08 41.26 49.55 29.85 26.66 23.23 16.01 28.44 29.07 37.21 22.36 17.82
17.14 11.22 8.74 6.47 9.82 6.11 5.95 8.05 6.46 7.55 9.3 6.72
29.86 18.11 21.58 13.25 18.06 16.95 17.55 19.24 19.75 19.15 19.74 15.51
161.72 4.98 175.31 190.83 162.31 133.47 193.87 146.93 196.89 128.79 161.11 176.42
19.94 11.32 20.4 22.6 18.15 17.86 24.36 19.57 22.0 19.63 19.79 20.16
15.61 10.19 5.17 5.94 4.4 3.22 2.53 5.31 4.11 8.08 5.34 6.45
11.04 6.41 6.38 5.83 7.57 5.6 4.88 6.29 6.02 3.8 6.42 4.71
11.86 10.3 8.85 6.26 9.89 6.26 9.72 11.91 6.72 5.17 11.03 8.38
187.96 178.01 176.14 185.18 188.12 165.96 166.43 185.59 183.38 211.54 185.48 172.86
33.81 15.31 25.78 25.15 21.3 20.46 26.4 21.93 26.58 21.83 22.71 24.75
513.63 298.41 470.12 466.98 498.38 418.56 504.33 534.03 454.89 399.43 496.96 460.43
19.91 12.51 12.24 16.21 14.31 12.35 14.58 16.81 14.81 14.11 15.29 12.05
46.32 43.1 26.97 21.32 33.17 21.89 23.19 33.49 26.66 24.69 32.55 20.77
115.41 63.23 109.63 97.84 98.13 84.05 91.62 93.37 104.24 93.71 104.49 101.15
95.43 51.67 70.35 72.46 79.2 69.39 84.41 80.16 74.68 62.86 81.68 66.03
16.91 14.05 7.31 4.56 6.78 2.13 4.21 5.26 4.95 7.38 7.51 6.12
339.23 297.86 225.23 163.2 245.25 241.17 192.55 246.02 202.22 243.29 231.98 204.76
115.14 58.35 85.99 76.55 69.36 65.66 90.1 76.1 68.93 85.09 78.88 81.51
47.35 28.74 32.62 36.06 32.49 28.44 37.91 35.66 34.42 28.56 31.19 33.55
106.55 10.08 25.71 49.92 37.03 40.75 54.91 52.47 34.36 40.71 54.55 58.34
41.92 31.25 35.8 30.89 39.2 29.89 40.43 39.05 35.24 40.07 37.39 35.79

Details

Raw expression values (TPM normalized), Green cells indicate low expression and red high. (Dark gray cells indicate missing values)