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GO:0008534: oxidized purine nucleobase lesion DNA N-glycosylase activity (Molecular function)

"Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site." [GOC:elh, PMID:11554296]


There are 642 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_141 Chlamydomonas reinhardtii 1.23 % 0.004566 0.027394
Cluster_150 Chromochloris zofingiensis 1.14 % 0.005726 0.049929
Cluster_148 Seminavis robusta 0.67 % 0.00395 0.022296
Sequences (642) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms