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GO:0007186: G protein-coupled receptor signaling pathway (Biological process)

"A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane." [GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor]


There are 4294 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_142 Chlamydomonas reinhardtii 1.89 % 0.005966 0.041763
Cluster_200 Chlorella vulgaris 1.67 % 0.00439 0.032562
Cluster_601 Cladocopium sp. clade C 50.0 % 0.000334 0.002339
Cluster_854 Cladocopium sp. clade C 50.0 % 0.000334 0.002673
Cluster_241 Emiliania huxleyi 2.47 % 0.000194 0.034153
Cluster_65 Haematococcus lacustris 1.82 % 0.001945 0.039222
Cluster_93 Phaeodactylum tricornutum 2.94 % 0.001343 0.038055
Cluster_31 Phaeodactylum tricornutum 2.67 % 0.001631 0.009572
Cluster_96 Seminavis robusta 8.2 % 7.1e-05 0.002489
Cluster_452 Seminavis robusta 50.0 % 0.014002 0.044808
Cluster_316 Seminavis robusta 5.45 % 0.006873 0.021851
Cluster_175 Seminavis robusta 3.17 % 0.012223 0.03115
Cluster_265 Seminavis robusta 8.06 % 7.7e-05 0.000504
Cluster_226 Seminavis robusta 4.48 % 0.011801 0.030587
Cluster_388 Seminavis robusta 50.0 % 0.014002 0.044808
Cluster_150 Seminavis robusta 4.84 % 0.009558 0.034136
Cluster_136 Seminavis robusta 6.67 % 0.00019 0.006782
Cluster_322 Seminavis robusta 4.62 % 0.010871 0.044163
Cluster_254 Seminavis robusta 3.33 % 0.010362 0.041449
Cluster_557 Seminavis robusta 50.0 % 0.014002 0.044808
Cluster_275 Seminavis robusta 3.24 % 0.002048 0.009666
Cluster_149 Seminavis robusta 2.6 % 0.006051 0.033383
Cluster_259 Seminavis robusta 6.72 % 0.0 5e-06
Cluster_34 Seminavis robusta 5.17 % 0.00796 0.03343
Sequences (4294) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms