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GO:0005852: eukaryotic translation initiation factor 3 complex (Cellular component)

"A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs." [PMID:15904532]


There are 3367 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_45 Cyanophora paradoxa 0.83 % 9.4e-05 0.000666
Cluster_68 Chlamydomonas reinhardtii 1.92 % 0.002931 0.005152
Cluster_65 Chlorella sorokiniana 1.85 % 0.020643 0.049401
Cluster_27 Chlorella sorokiniana 1.96 % 0.000566 0.003137
Cluster_152 Chlorella vulgaris 1.72 % 0.000107 0.000552
Cluster_26 Chromochloris zofingiensis 1.14 % 0.00126 0.007022
Cluster_69 Chromochloris zofingiensis 4.55 % 8e-05 0.013862
Cluster_194 Emiliania huxleyi 1.25 % 0.014436 0.039038
Cluster_89 Haematococcus lacustris 1.54 % 0.013713 0.037461
Cluster_38 Haematococcus lacustris 3.64 % 5.5e-05 0.000478
Cluster_196 Haematococcus lacustris 3.28 % 6.8e-05 0.000962
Cluster_56 Micromonas commoda 3.45 % 9.8e-05 0.003349
Cluster_6 Micromonas pusilla 0.93 % 0.00256 0.013565
Cluster_15 Ostreococcus tauri 0.85 % 0.005342 0.029973
Cluster_42 Phaeodactylum tricornutum 4.0 % 1e-06 5e-06
Cluster_53 Seminavis robusta 0.68 % 0.015499 0.046213
Cluster_97 Seminavis robusta 1.49 % 0.007087 0.013458
Cluster_139 Seminavis robusta 1.15 % 0.000126 0.001139
Cluster_9 Thalassiosira pseudonana 1.65 % 4e-06 6.4e-05
Sequences (3367) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms