GO:0005085: guanyl-nucleotide exchange factor activity (Molecular function)

"Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions." [GOC:kd, GOC:mah, PMID:23303910, PMID:27218782]

There are 257 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Sequences (257) (download table)

InterPro Domains

GO Terms

Family Terms