"A eukaryotic vacuolar membrane-associated protein; in humans, it is comprised of LAMTOR1, LAMTOR2, LAMTOR3, LAMTOR4, and LAMTOR5. In budding yeast, S. cerevisiae, this complex includes Gtr1p, Gtr2p, Meh1p, and Slm4p. The complex is anchored to lipid rafts in vacuole/lysosome membrane via LAMTOR1 and acts as a guanine nucleotide exchange factor (GEF) for the Rag GTPases." [GOC:krc, GOC:lb, GOC:vw, PMID:15989961, PMID:16732272, PMID:19177150, PMID:19748353, PMID:20381137, PMID:22980980, PMID:29199950]
There are 288 sequences with this label.